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Barbital

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Identification
Molecular formula
C8H12N2O3
CAS number
57-44-3
IUPAC name
5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, barbital is in a solid state. It is commonly utilized in its powdered form for various applications. The compound is stable under standard conditions and requires specific storage conditions to preserve its integrity.

Melting point (Celsius)
191.50
Melting point (Kelvin)
464.65
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.15
General information
Molecular weight
184.20g/mol
Molar mass
184.2240g/mol
Density
1.0685g/cm3
Appearence

Barbital is typically found as a white, crystalline powder. It is odorless and has a slightly bitter taste. The compound is known for its high purity and fine crystal structure.

Comment on solubility

Solubility of 5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione is influenced by various factors including its molecular structure and polarity. Here are some key points regarding its solubility:

  • Polar Interactions: The presence of multiple polar functional groups in the molecule suggests that it may exhibit some degree of solubility in polar solvents such as water.
  • Hydrophobic Characteristics: The butyl and ethyl substituents can add hydrophobic character, potentially limiting solubility in predominantly polar solvents.
  • Solvent Compatibility: It is expected to be more soluble in organic solvents like ethanol or methanol compared to water, considering its structural features.
  • pH Dependence: Changes in the pH of the solution could also affect solubility due to protonation or deprotonation of the functional groups.

In summary, while the solubility profile of 5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione can be complex, it demonstrates significant variability based on solvent choice and environmental conditions. Understanding these factors is crucial for practical applications of this compound in various chemical environments.

Interesting facts

Interesting Facts about 5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione

5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione is a fascinating chemical compound that belongs to the class of pyrimidines. This compound is particularly interesting due to the following reasons:

  • Structural Complexity: The presence of multiple substituents, such as butyl and ethyl groups, adds layers of complexity to its structure, influencing its chemical behavior and reactivity.
  • Biological Relevance: Pyrimidines are essential components of nucleic acids (DNA and RNA). As a derivative of pyrimidine, this compound may hold potential biological applications or serve as a model for studying nucleobase interactions.
  • Reactivity: The hexahydropyrimidine core can participate in various chemical reactions due to its tetrahedral structure, making it a versatile compound in organic synthesis. This enables the connection to both medicinal chemistry and materials science.
  • Potential Applications: Compounds like this can be explored for their potential use in pharmaceuticals as they may exhibit various biological activities, including antimicrobial or antitumor properties. Their design often aims to enhance pharmacological efficacy.

As a scientist or chemistry student, one might express their curiosity about this compound with a quote: "The beauty of chemistry lies not only in the simplicity of elemental interactions but in the intricate dance of complex molecules that can alter the fabric of life itself."

The study of 5-butyl-5-ethyl-hexahydropyrimidine-2,4,6-trione exemplifies how even seemingly complicated structures can pave the way for innovative research avenues and advancements in the field of chemistry.

Synonyms
Butethal
Butobarbital
Butobarbitone
Butobarbitural
Soneryl
Hyperbutal
Etoval
Neonal
Longanoct
Monodorm
Sonerile
Budorm
77-28-1
Butobarbitalum
5-BUTYL-5-ETHYLBARBITURIC ACID
Meonal
5-Ethyl-5-butylbarbituric acid
Butabarbitol
5-Ethyl-5-n-butylbarbituric acid
Aethylbutylbarbitursaeure
5-butyl-5-ethyl-1,3-diazinane-2,4,6-trione
Neonal (TN)
Butobarbital (BAN)
Butyl,5-ethylbarbituric acid
5-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
UNII-OHZ8QAW6YC
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-5-ethyl-
Butobarbital [INN:BAN]
Barbituric acid, 5-butyl-5-ethyl-
EINECS 201-019-9
NSC 229336
NSC-229336
BRN 0201786
OHZ8QAW6YC
BUTETHAL [MI]
BUTOBARBITAL [MART.]
BUTOBARBITAL [WHO-DD]
DTXSID70227808
5-24-09-00161 (Beilstein Handbook Reference)
BUTOBARBITAL (MART.)
Butobarbital (1.0 mg/ml in Methanol)
Butethal [NF]
butethal, monosodium salt
SCHEMBL44262
CHEMBL404422
DTXCID80150299
CHEBI:134884
WLN: T6VMVMV FHJ F4 F2
Butobarbital 0.1 mg/ml in Methanol
Butobarbital 1.0 mg/ml in Methanol
NSC229336
AKOS005256452
DB01353
NS00003503
D02618
5-Butyl-5-A currencythyl-barbitursA currencyure
SR-01000883936
Q3395266
SR-01000883936-1
2,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-5-ethyl-
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-butyl-5-ethyl-