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5-Bromoindoline-2,3-dione

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Identification
Molecular formula
C8H4BrNO2
CAS number
81-68-5
IUPAC name
5-bromoindoline-2,3-dione
State
State

At room temperature, 5-Bromoindoline-2,3-dione is typically in a solid state. It should be stored in airtight containers to avoid degradation when exposed to moisture or light, which can alter its chemical properties.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
242.01g/mol
Molar mass
242.0080g/mol
Density
3.2908g/cm3
Appearence

5-Bromoindoline-2,3-dione appears as a yellowish to brown crystalline solid. Its crystalline structure is often used in the development of dyes and pigments due to its vibrant appearance. The compound can form well-defined crystals, making it significant in material sciences.

Comment on solubility

Solubility Characteristics of 5-bromoindoline-2,3-dione

5-bromoindoline-2,3-dione, a compound notable for its unique chemical structure, exhibits specific solubility properties. Understanding its solubility can provide valuable insights for applications in various fields. Here’s what we know:

  • Polar Solvents: 5-bromoindoline-2,3-dione is generally more soluble in polar solvents due to its ability to form hydrogen bonds. Water and methanol are good examples where solubility is enhanced.
  • Non-Polar Solvents: The solubility in non-polar solvents is comparatively lower. Solvents like hexane and benzene show limited interaction, thus reducing the solubility of this compound.
  • Temperature Sensitivity: Solubility may also vary with temperature. An increase in temperature generally improves solubility in most solvents.
  • pH Dependence: The solubility can be influenced by the pH of the solution, particularly in aqueous environments. A more acidic or basic medium can change the charge state of the molecule, which in turn affects solubility.

In summary, while 5-bromoindoline-2,3-dione is generally soluble in polar solvents and shows increased solubility with rising temperatures, its solubility in non-polar systems remains limited. Understanding these properties can be crucial for its application in scientific research and industry.

Interesting facts

Exploring 5-Bromoindoline-2,3-dione

5-Bromoindoline-2,3-dione is a fascinating compound that has garnered attention in the realms of organic chemistry and medicinal research. Here are some intriguing facts about this compound:

  • Structural Significance: This compound features a unique indoline core which is pivotal in many biological activities. Its structure includes a bromine atom, which can significantly enhance the compound's reactivity and potential applications in synthesis.
  • Potential Biological Activities: 5-Bromoindoline-2,3-dione and its derivatives have been studied for their antimicrobial and antitumor properties. Researchers are particularly interested in how the introduction of bromine might influence its pharmacological profile.
  • Synthetic Utility: The compound serves as a building block in organic synthesis, showcasing its importance in the development of various molecules. Its reactivity allows for the introduction of diverse functional groups, making it a pivotal compound in the design of more complex chemical entities.
  • Research Applications: The investigation of this compound contributes to the broader field of medicinal chemistry, where understanding structure-activity relationships is key. Its derivatives may offer insights into new therapeutic avenues for treating a range of diseases.
  • Advancements in Materials Science: Beyond its biological applications, this compound has potential uses in materials science, especially in the creation of organic semiconductors due to its planar structure and ability to form π-stacks.

In summary, 5-Bromoindoline-2,3-dione is much more than just a chemical entity. Its diverse potential applications across various fields make it a subject of continued interest for both chemists and researchers alike.

Synonyms
5-Bromoisatin
87-48-9
5-Bromoindoline-2,3-dione
5-Bromo-1H-indole-2,3-dione
5-Bromoindole-2,3-dione
Isatin, 5-bromo-
5-Bromisatin
1H-Indole-2,3-dione, 5-bromo-
5-Bromisatin [Czech]
Bromoisatin
NSC 4980
5-bromo-2,3-dihydro-1H-indole-2,3-dione
EINECS 201-747-7
INDOLE-2,3-DIONE, 5-BROMO-
BRN 0383760
5-bromo-2-hydroxy-3H-indol-3-one
DTXSID30236037
5-21-10-00264 (Beilstein Handbook Reference)
NSC-4980
5-bromo isatin
5-bromo-isatin
MFCD00005719
Indole-2, 5-bromo-
Isatin-based compound, 34
1H-Indole-2, 5-bromo-
5-Bromo-2,3-indolinedione
DZU75P8VY8
WLN: T56 BMVVJ GE
SCHEMBL136581
5-bromo-1H-indole-2,3dione
CHEMBL115897
BDBM22814
DTXCID30158528
NSC4980
CHEBI:149786
5-Bromo -1H-indole-2,3-dione
5-Bromo-1H-indole-2,3-dione #
BCP04280
STR04158
MFCD00149345
STK364356
STL140691
5-Bromoisatin, technical grade, 90%
AKOS000200674
AKOS002375882
CS-W007383
FB19242
FS-2520
SB66105
1H-Indole-2,3-dione, 5-bromo-(9CI)
AC-14581
DB-026328
B1566
NS00039198
EN300-18123
F11278
SR-01000402436
SR-01000402436-1
Z57833927
F0900-5717
5-Bromo-indole-2,3-dione;5-Bromo-isatin;5-Bromo-1H-indole-2,3-dione
201-747-7