Interesting facts
Interesting Facts about 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
This intriguing compound belongs to the class of quinoxaline derivatives, which have garnered significant attention in the field of medicinal chemistry due to their diverse biological activities. Here are some fascinating aspects of 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine:
- Bioactive Potential: Compounds like this one have been studied for their potential as anti-cancer agents. Their ability to interact with biological pathways makes them of great interest for drug design.
- Electrophilic Nature: The presence of the bromine atom suggests heightened electrophilic properties, which can enhance the compound's reactivity in various chemical transformations.
- Imidazole Motif: The inclusion of a dihydroimidazole group contributes to the overall stability and solubility, which is critical in optimizing the pharmacokinetic properties of potential drug candidates.
- Versatile Synthesis: This compound can be synthesized through various methods, including multi-step reactions that are commonly employed in medicinal chemistry, showcasing the creativity and innovation in synthetic pathways.
- Potential Applications: Beyond anti-cancer properties, research indicates that quinoxaline derivatives may possess anti-inflammatory, antimicrobial, and anti-viral activities.
In summary, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine stands out due to its complex structure and potential therapeutic benefits. As researchers continue to explore its properties, it may pave the way for developing new medicinal treatments that address critical health challenges.
Synonyms
brimonidine
59803-98-4
UK 14,304
Bromoxidine
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine
brimonidina
brimonidinum
5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
UK-14304
6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-
AGN 190342
E6GNX3HHTE
UNII-E6GNX3HHTE
UK 14304
MFCD00153878
NSC-318825
BRN 0751629
CHEBI:3175
MLS000069370
AGN-190342 FREE BASE
LK 14304-18
UK-1430418 FREE BASE
CHEMBL844
SMR000058355
DTXSID3045221
Brimonidine (INN)
NSC 318825
NCGC00016069-09
UK14,304
UK 14304;AGN190342
BRIMONIDINE [INN]
UK 14304 (tartrate);AGN190342 (tartrate)
5-Bromo-N-(2-imidazolin-2-yl)-6-quinoxalinamine
DTXCID1025221
Brimonidine [INN:BAN]
6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-, (S-(R*,R*))-2,3-dihydroxybutanedioate (1:1)
CAS-59803-98-4
SR-01000000023
AGN-190342
Brimodine
5-bromo-6-(imidazolidinylideneamino)quinoxaline
UK14304
Brimonidine (Standard)
Tocris-0425
[3H]-UK14304
Opera_ID_612
Lopac-U-104
BRIMONIDINE [MI]
brimonidine (UK14304)
BRIMONIDINE [VANDF]
cid_2435
Lopac0_001216
SCHEMBL24670
BRIMONIDINE [WHO-DD]
GTPL520
MLS001076349
BIDD:GT0649
GTPL5386
BDBM34572
HY-B0659R
[3H]brimonidine (UK14304)
D11AX21
S01EA05
XYLJNLCSTIOKRM-UHFFFAOYSA-N
HMS3259P09
HMS3263D14
HMS3266O03
HMS3411K05
HMS3675K05
HMS3887K07
BCP12632
EX-A5415
HY-B0659
Tox21_110299
Tox21_501216
AC-162
NSC318825
PDSP1_000640
PDSP2_000635
s9508
AKOS005267239
Brimonidine;AGN190342;UK14304
Tox21_110299_1
CCG-205290
DB00484
FB19008
GS-3236
LP01216
NC00638
SDCCGSBI-0051183.P002
MRF-0000657
NCGC00016069-01
NCGC00016069-02
NCGC00016069-03
NCGC00016069-04
NCGC00016069-05
NCGC00016069-06
NCGC00016069-07
NCGC00016069-08
NCGC00016069-10
NCGC00016069-11
NCGC00016069-12
NCGC00016069-13
NCGC00016069-24
NCGC00023468-02
NCGC00023468-04
NCGC00023468-05
NCGC00023468-06
NCGC00023468-07
NCGC00261901-01
SY053060
Brimonidine 100 microg/mL in Acetonitrile
B4132
EU-0101216
NS00006954
EN300-50880
UK 14304-18
C07886
C75796
D07540
5-bromo-6-(2-imidazolidinylidenamino)quinoxaline
5-bromo-6-(2-imidazolin-2-ylamino) quinoxaline
5-Bromo-6-(2-imidazolin-2-ylamino)-quinoxaline
6-Quinoxalinamine,5-dihydro-1H-imidazol-2-yl)-
A832477
L000615
Q577377
SR-01000000023-2
SR-01000000023-4
BRD-K68264559-001-10-0
BRD-K68264559-001-13-4
BRD-K68264559-045-02-4
BRD-K68264559-045-03-2
BRD-K68264559-045-04-0
5-Bromo-N-(4,5-dihydro-2-imidazolyl)quinoxalin-6-amine
Z608061562
(5-Bromo-quinoxalin-6-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine
5-bromanyl-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
5-BROMO-6-(2-IMIDAZOLIN-2-YLAMINO)QUINOXALINE D-TARTRATE (1:1).
6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)- (9CI)
5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine;5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
Solubility of 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
The solubility of the compound 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine (C11H10BrN5) can be influenced by several factors:
In general, compounds characterized by complex heterocyclic structures like this one often show varied solubility profiles across different solvents. As a result, finding the right solvent involves experimentation. Researchers might typically find that:
In conclusion, while the precise solubility of this compound requires experimental determination, understanding these influencing factors can provide valuable insight into its potential behavior in various environments.