5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one

Identification

Molecular formula

C₁₆H₁₃BrN₂O

CAS number

4378-41-0

IUPAC name

5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one

State

This compound is typically in a crystalline solid state at room temperature.

Melting point (Celsius)

257.00

Melting point (Kelvin)

530.00

Boiling point (Celsius)

538.00

Boiling point (Kelvin)

811.00

General information

Molecular weight

309.19g/mol

Molar mass

309.1460g/mol

Density

1.4342g/cm³

Appearence

5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one appears as a pale yellow to off-white crystalline solid. Its structure includes a fused indoline system with a bromo substitution, giving it a distinctive color and appearance.

Comment on solubility

Solubility of 5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one

The solubility of the compound 5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one (C₁₆H₁₃BrN₂O) can be assessed considering several key factors that influence its behavior in various solvents. Understanding its solubility is vital for practical applications and chemical reactions.

Factors Influencing Solubility

Polarity: The general rule that "like dissolves like" applies here. The presence of the bromine atom and the indole moiety contribute to both polar and non-polar characteristics of the molecule, possibly leading to varied solubility in different solvents.
Hydrogen Bonding: The indole structure can potentially engage in hydrogen bonding, which may enhance solubility in polar solvents such as water or alcohols.
Alkyl Chains: The length and branching of any alkyl chains can also affect solubility, potentially making the compound more soluble in organic solvents.

In general, compounds of this nature tend to demonstrate limited solubility in water but may be more soluble in organic solvents such as dimethylsulfoxide (DMSO) or ethanol. As per the structure, one might anticipate solubility in non-polar solvents to vary based on the interaction of the halogen and the indole-based functionalities.

In conclusion, while the solubility studies would require experimental validation for precise data, it can be posited that the solubility of this compound is likely influenced by its unique chemical structure and functional groups.

Interesting facts

Interesting Facts about 5-Bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one

5-Bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one is a fascinating compound known for its diverse potential applications in medicinal chemistry and organic synthesis. Here are some intriguing aspects of this compound:

Diverse Structures: This compound contains both indolin and indole structures, which are commonly found in a variety of natural products and pharmaceuticals.
Potential Biological Activity: The structural characteristics of this compound suggest potential activity against various biological targets, making it a subject of interest for drug discovery.
Halogenation Influence: The presence of the bromine atom not only adds to the compound's reactivity but may also influence its interaction with biological systems, which is crucial in medicinal chemistry.
Synthetic Utility: Its synthesis can involve various modern organic reactions, showcasing the versatility and creativity in synthetic organic chemistry practices.

The study of compounds like 5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)indolin-2-one expands our understanding of chemical behavior and opens new doors in the quest for effective pharmaceuticals. As one chemical researcher aptly noted, "Every compound tells a story of its reactivity and potential utility." Through deeper exploration, we can uncover those narratives and harness the power of such compounds in meaningful ways.

Synonyms

5-Bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one

204003-89-4

DTXSID001132062