Interesting facts
Interesting Facts about 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-indole-4,7-dione
This intriguing compound is part of the indole family, which is known for its diverse biological activities and structural complexity. Here are some fascinating aspects:
- Pharmacological Potential: Compounds containing the indole ring exhibit a range of biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties. This specific compound with an aziridine moiety suggests potential applications in targeted drug delivery and cancer therapy.
- Unique Structural Features: The presence of the aziridinyl group in the structure makes this compound particularly interesting as aziridines are known for their reactivity and ability to participate in various chemical reactions, including being used as intermediates in organic synthesis.
- Functionalization: The compound features multiple hydroxymethyl groups, which can enhance its solubility and bioavailability, potentially leading to more effective therapeutic agents.
- Indole Interaction: The indole portion of the molecule can engage in significant π-π stacking interactions, potentially influencing the interaction with biological targets, such as receptors and enzymes.
- Research Significance: Given the complexity of this compound, it serves as a valuable subject for medicinal chemistry studies aimed at exploring new pharmacophore designs and synthesis methodologies.
Overall, 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-indole-4,7-dione embodies a combination of structural diversity and potential therapeutic significance, making it a compound worth exploring in depth within the field of chemistry.
Synonyms
3-hydroxymethyl-5-aziridinyl-1methyl-2-[1h-indole-4,7-dione]-propanol
3-Hydroxymethyl-5-Aziridinyl-1methyl-2-(1h-Indole-4,7-Dione)-Propanol
SCHEMBL4466055
DB02395
PD008370
NS00070007
Q27093397
5-aziridin-1-yl-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-1H-indole-4,7-dione
5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-4,7-dihydro-1h-indole-4,7-dione
Solubility of 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-indole-4,7-dione
The solubility of the compound 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-indole-4,7-dione (C15H18N4O5) is influenced by several key factors:
Overall, while the molecule has elements that may facilitate solubility in polar solvents, the hydrophobic segments can hinder complete dissolution. As a rule of thumb, "like dissolves like;" thus, its solubility will be better in solvents that can engage with both polar and non-polar characteristics. Researchers often find that the absence of empirical data on solubility necessitates experimental validation to accurately determine its behavior in different solvents.
In conclusion, understanding the solubility of this compound involves considering its chemical structure, the influence of solvent polarity, and the conditions under which dissolution is attempted. Experimentation is key in revealing the true solubility profile of 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-1-methyl-indole-4,7-dione.