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Valine

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Identification
Molecular formula
C5H11NO2
CAS number
74-88-4
IUPAC name
5-aminopentanoic acid
State
State

At room temperature, valine is a solid.

Melting point (Celsius)
298.15
Melting point (Kelvin)
571.30
Boiling point (Celsius)
290.15
Boiling point (Kelvin)
563.30
General information
Molecular weight
117.15g/mol
Molar mass
117.1460g/mol
Density
1.0461g/cm3
Appearence

Valine appears as white, water-soluble crystals or crystalline powder.

Comment on solubility

Solubility of 5-Aminopentanoic Acid (C5H11NO2)

5-Aminopentanoic acid, also known as aminopentanoic acid, exhibits interesting solubility properties that are influenced by its molecular structure. This compound contains both an amine group and a carboxylic acid group, which can strongly affect its interactions with water.

Key Points on Solubility:

  • Aqueous Solubility: 5-aminopentanoic acid is readily soluble in water due to the ability of the polar carboxylic acid and amine groups to form hydrogen bonds with water molecules.
  • pH Dependence: The solubility can vary with pH; in acidic conditions, the carboxyl group is generally protonated, leading to different solubility behaviors than in neutral or basic environments.
  • Organic Solvents: It may have limited solubility in non-polar organic solvents, which reflects the hydrophilic nature of the functional groups.

As a result, 5-aminopentanoic acid is a prime example of how the functional groups within a compound dictate solubility characteristics. This solubility can be summarized as:

  1. High solubility in water due to hydrogen bonding.
  2. Varied solubility in different pH environments.
  3. Limited solubility in non-polar solvents.

Understanding these solubility traits is crucial, as they influence the compound's behavior in biological systems, industrial applications, and various chemical processes.

Interesting facts

Interesting Facts about 5-Aminopentanoic Acid

5-Aminopentanoic acid, commonly known as 5-APA, is a fascinating compound with various implications in both scientific research and practical applications. This compound is a type of amino acid, characterized by its unique linear structure. Here are some intriguing aspects of 5-aminopentanoic acid:

  • Biological Importance: 5-APA plays a role in the synthesis of neurotransmitters and is involved in various metabolic pathways. Its ability to affect neurological functions makes it a compound of interest in neuropharmacology.
  • Building Block: The compound can serve as a building block for the synthesis of peptides and other bioactive molecules, opening possibilities in drug development and biochemical research.
  • Research Applications: It has been studied for its potential applications in treating neurological disorders, showcasing its significance in the pharmaceutical industry. Researchers are investigating its effects on conditions like epilepsy and mood disorders.
  • Derivatives: The derivatives and analogs of 5-APA have been synthesized for enhanced biological activity, highlighting the richness of chemistry in generating compounds with specific desired pharmacological effects.
  • General Observations: Like other amino acids, 5-APA can undergo various chemical reactions, including esterification and amination, which contribute to its versatility as a reagent in chemical synthesis.

In summary, 5-aminopentanoic acid is not just an amino acid; it is a compound with potential breakthroughs in health sciences, offering a glimpse into the multifaceted world of organic chemistry and its applications in improving human health.

Synonyms
5-Aminovaleric acid
5-Aminopentanoic acid
660-88-8
Pentanoic acid, 5-amino-
Homopiperidinic acid
H-5-Ava-OH
5-amino-pentanoic acid
delta-Aminovaleric acid
Valeric acid, 5-amino-
delta-Amino-n-valeric acid
5-aminopentanoate
5-AMINO-N-VALERIC ACID
DAVA
MFCD00008232
5-aminovalerate
CHEBI:15887
Delta-Aminovalerianic Acid
DANVA
5-ammoniopentanoate
EINECS 211-544-5
NSC 58383
NSC 73123
.delta.-Aminovaleric acid
.delta.-Amino-n-valeric acid
CHEMBL284116
DTXSID70216212
NSC-58383
NSC-73123
delta-aminovalerate
delta-Amino-n-valerate
Valeric acid, 5-amino- (8CI)
Pentanoic acid, 5-amino- (9CI)
5-Aminopentanoicacid
5-amino valeric acid
5-amino-valeric acid
omega-aminovaleric acid
Spectrum_001627
5-Amino pentanoic acid
BUW4BFJ6SC
SpecPlus_000854
delta-aminopentanoic acid
omega-Aminopentanoic acid
Spectrum2_001410
Spectrum3_001447
Spectrum4_001015
Spectrum5_001809
5-amino-n-pentanoic acid
bmse000957
bmse000990
Lopac-194336
H2N(CH2)4COOH
5-Aminovaleric acid, 97%
NCIOpen2_000480
Valeric acid, (5-amino)-
Lopac0_000031
BSPBio_002913
KBioGR_001509
KBioSS_002107
DivK1c_006950
SCHEMBL190150
SPBio_001460
Valeric acid, 5-amino-(8CI)
KBio1_001894
KBio2_002107
KBio2_004675
KBio2_007243
KBio3_002413
DTXCID70138703
Pentanoic acid, 5-amino-(9CI)
NSC58383
NSC73123
BBL027702
BDBM50026409
LMFA01100040
STL257473
AKOS009140748
CCG-204127
CS-W016594
FA13122
HY-W015878
RS-1002
SDCCGMLS-0412455.P029
SDCCGSBI-0050020.P003
MLS-0412455
NCGC00014991-01
NCGC00014991-02
NCGC00014991-03
NCGC00014991-05
NCGC00162049-01
BP-13016
SY002964
5-Aminopentanoic acid;Homopiperidinic acid
DB-054865
A0663
NS00014752
EN300-28602
C00431
D78140
Q11751639
F8889-6991
Z271111992
F8D56633-B691-4612-9B69-981EF090A047
211-544-5