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5-(aminomethyl)-3-isoxazolone

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Identification
Molecular formula
C4H6N2O2
CAS number
1707-02-6
IUPAC name
5-(aminomethyl)isoxazol-3-one
State
State

At room temperature, 5-(aminomethyl)-3-isoxazolone is generally found in a solid crystalline state.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
337.50
Boiling point (Kelvin)
610.65
General information
Molecular weight
112.11g/mol
Molar mass
112.1070g/mol
Density
1.3200g/cm3
Appearence

The compound 5-(aminomethyl)-3-isoxazolone typically appears as a crystalline solid. The color may vary from white to off-white depending on the purity and form.

Comment on solubility

Solubility of 5-(aminomethyl)isoxazol-3-one

The solubility of 5-(aminomethyl)isoxazol-3-one (C4H6N2O2), a compound featuring both amino and isoxazole functional groups, is quite interesting due to its structural characteristics. Generally, the solubility of organic compounds can be influenced by several factors:

  • Polarity: The presence of polar functional groups, such as the amine and carbonyl, often enhances solubility in polar solvents like water.
  • Hydrogen Bonding: This compound is capable of forming hydrogen bonds, which can further increase its solubility in compatible solvents.
  • Molecular Size: With a molecular weight of only 102.10 g/mol, smaller compounds generally have better solubility compared to larger, bulky compounds.

As a result, it can be anticipated that 5-(aminomethyl)isoxazol-3-one exhibits moderate to high solubility in polar solvents, especially in water. However, its solubility may vary based on temperature and the presence of other solutes. In summary, one could say that:

"The solubility of 5-(aminomethyl)isoxazol-3-one speaks to the intricate dance of molecular interactions, where polar characteristics rule the day!"
Interesting facts

Interesting Facts about 5-(Aminomethyl)isoxazol-3-one

5-(Aminomethyl)isoxazol-3-one is a fascinating compound with several notable properties and applications in the realm of chemistry. This compound is particularly interesting for its unique structure and potential biological activity. Here are some intriguing aspects:

  • Structural Significance: The isoxazole ring is a significant feature of this compound. Isoxazoles are known for their diverse reactivity, which has implications in medicinal chemistry.
  • Biological Relevance: Compounds containing the isoxazole ring have been explored for their therapeutic potential, including anti-inflammatory and antibacterial properties. The presence of the aminomethyl group can enhance these activities.
  • Pharmaceutical Applications: Research has indicated that similar compounds containing the isoxazole moiety may act as enzyme inhibitors, making them candidates for drug development.
  • Research Insight: Studies have shown that derivatives of 5-(aminomethyl)isoxazol-3-one can exhibit significant biological effects, prompting ongoing investigations into their mechanisms of action.
  • Chemical Versatility: The functional groups present in this compound allow for various chemical modifications, enabling chemists to design new derivatives with tailored properties. This versatility is a key asset in synthetic chemistry.

To summarize, 5-(Aminomethyl)isoxazol-3-one serves as an excellent example of how a seemingly simple compound can possess a wealth of potential applications. As we delve deeper into its properties and reactivities, we are likely to uncover even more transformative uses in modern science.

Synonyms
muscimol
2763-96-4
Agarin
Pantherine
Agarine
3(2H)-Isoxazolone, 5-(aminomethyl)-
5-Aminomethyl-3-hydroxyisoxazole
Pantherin
3-Hydroxy-5-aminomethylisoxazole
5-(Aminomethyl)-3(2H)-isoxazolone
5-(Aminomethyl)-3-isoxazolol
5-Aminomethyl-3-isoxyzole
3-Isoxazolol, 5-(aminomethyl)-
RCRA waste number P007
NSC 333569
CCRIS 3720
CHEBI:7035
3-Hydroxy-5-aminomethylisoxazole-agarin
HSDB 6036
3-Hydroxy-5-aminomethyl-isoxazole
EINECS 220-430-4
5-(aminomethyl)-1,2-oxazol-3-one
MFCD00057894
5-(Aminomethyl)isoxazol-3-ol hydrate
NSC-333569
D5M179TY2E
MUSCIMOL [HSDB]
MUSCIMOL [MI]
5-(aminomethyl)-1,2-oxazol-3-ol
CHEMBL273481
DTXSID5041069
5-(Aminomethyl)isoxazol-3(2H)-one
5-(aminomethyl)isoxazol-3-ol
5-(aminomethyl)-1,2-oxazol-3(2H)-one
5-(aminomethyl)-2,3-dihydro-1,2-oxazol-3-one
RCRA waste no. P007
5-Aminomethyl-3-isoxazolol
UNII-D5M179TY2E
5-(aminomethyl)isoxazol-3-one
SR-01000075619
Muscimol, powder
5-Aminomethyl-3-hydroxy-isoxazole
[3H]muscimol
Agarin hydrobromide
[3H]-muscimol
[3 H]-muscimol
ZINC22064260
5Aminomethyl3isoxyzole
Tocris-0289
Lopac-G-019
5(Aminomethyl)3isoxazolol
Biomol-NT_000255
3Hydroxy5aminomethylisoxazole
5Aminomethyl3hydroxyisoxazole
Lopac0_000591
3Isoxazolol, 5(aminomethyl)
WLN: T5NOJ C1Z EQ
SCHEMBL149693
BPBio1_000926
GTPL4090
GTPL4259
5-(aminomethyl)-isoxazol-3-ol
DTXCID3021069
5(Aminomethyl)3(2H)isoxazolone
BDBM23183
BCPP000154
HMS3266G03
HMS3414F05
HMS3678F05
3(2H)Isoxazolone, 5(aminomethyl)
5(aminomethyl)-3(2h)-isooxazolone
BCP23771
BDBM50052792
HB0887
MSK7265-100M
NSC333569
AKOS006223439
AKOS022719658
5-Aminomethyl-3-isoxyzole hydrobromide
BCP9000968
CCG-204680
DB12458
FM26103
SDCCGSBI-0050573.P002
SMP1_000201
NCGC00015459-01
NCGC00015459-02
NCGC00015459-03
NCGC00015459-04
NCGC00015459-05
NCGC00024526-01
NCGC00024526-02
NCGC00024526-03
Muscimol Solution in Methanol, 100ug/mL
5-(Aminomethyl)-3-isoxazolol hydrobromide
NS00028339
UPCMLD00X18174-72-6:001
4-ISOXAZOLIN-3-ONE, 5-(AMINOMETHYL)-
C08311
EN300-333440
G85421
Q412504
SR-01000075619-3
BRD-K60441002-001-04-8
5-Aminomethyl-3-hydroxyisoxazole;5-(Aminomethyl)-3(2H)-isoxazolone;Agarin
3-Hydroxy-5-aminomethyl-isoxazole;5-Aminomethyl-3-isoxazolol;5-Aminomethyl-3-hydroxy-isoxazole