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Glutamic acid

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Identification
Molecular formula
C5H9NO4
CAS number
56-86-0
IUPAC name
5-amino-4-oxo-pentanoic acid
State
State

At room temperature, glutamic acid is typically a solid. It exists in the form of white crystals or powder, which is stable under normal conditions. It does not exhibit volatility and is not soluble in non-polar solvents.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
266.00
Boiling point (Kelvin)
539.15
General information
Molecular weight
131.13g/mol
Molar mass
131.1290g/mol
Density
1.5389g/cm3
Appearence

Glutamic acid is generally a white crystalline solid. It can also appear as a white powder, commonly provided in a granular form. It is commonly used in laboratories and is known for its ability to form crystals in solution.

Comment on solubility

Solubility of 5-amino-4-oxo-pentanoic acid

5-amino-4-oxo-pentanoic acid (C5H9NO4), known for its interactivity in biological systems, exhibits interesting solubility properties. This compound, being an amino acid derivative, typically demonstrates the following characteristics:

  • Solubility in Water: Due to the presence of amino (–NH2) and carboxyl (–COOH) functional groups, 5-amino-4-oxo-pentanoic acid is expected to be highly soluble in water. The polar nature of these groups facilitates hydrogen bonding with water molecules.
  • Influence of pH: The solubility can be significantly affected by the pH of the solution. In a neutral to slightly acidic environment, the compound remains protonated, enhancing solubility.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature; thus, higher temperatures could lead to greater dissolution.
  • Solvent Versatility: While it dissolves well in aqueous solutions, 5-amino-4-oxo-pentanoic acid may have limited solubility in non-polar solvents due to its polar functional groups.

In conclusion, the solubility of 5-amino-4-oxo-pentanoic acid is primarily influenced by its functional groups and environmental conditions, making it a notable compound for various applications, particularly in biochemical and pharmaceutical fields.

Interesting facts

5-Amino-4-oxo-pentanoic Acid: An Insightful Overview

5-Amino-4-oxo-pentanoic acid, often abbreviated as 5-AOPA, is an intriguing compound in the realm of organic chemistry. This compound serves as a versatile building block in various chemical and biochemical applications. Here are some compelling facts about this compound:

  • Amino Acids Connection: 5-AOPA is structurally related to amino acids, showcasing both an amino group and a carboxylic acid group. This dual nature makes it significant in protein synthesis and metabolic pathways.
  • Potential Therapeutic Applications: Research has highlighted its potential role in neurological studies, as it may play a part in neurotransmitter functions due to its structural resemblance to amino acids.
  • Biochemical Research: 5-AOPA has been investigated for its potential use as a precursor in the synthesis of more complex molecules, particularly those related to pharmaceuticals and agricultural chemicals.
  • Chiral Center Implications: The presence of a chiral center in 5-AOPA adds complexity to its behavior in biological systems, illustrating the importance of stereochemistry in drug design and efficacy.
  • Synthesis Methodologies: Synthetic routes to obtain 5-AOPA often involve various organic reactions, demonstrating the richness of synthetic organic chemistry methods.

In summary, 5-amino-4-oxo-pentanoic acid not only embodies a simple yet fascinating structure but also holds promise in various fields such as medicinal chemistry, biochemistry, and synthetic organic chemistry. Its unique properties make it an essential subject of study for chemists and biology researchers alike.

Synonyms
5-Aminolevulinic acid
Aminolevulinic acid
106-60-5
5-Amino-4-oxopentanoic acid
5-Aminolevulinate
Pentanoic acid, 5-amino-4-oxo-
delta-aminolevulinic acid
Aladerm
5-Amino-4-oxovaleric acid
5-ALA
Aminolevulinate
Kerastick
delta-ALA
5-amino-4-oxo-pentanoic acid
5-Aminolaevulinic acid
5-amino-levulinate
Levulinic acid, 5-amino-
D-aminolevulinic acid
5-amino-levulinic acid
CCRIS 8958
5-Amino-4-oxopentanoate
EINECS 203-414-1
Amino-levulinic acid
DALA
UNII-88755TAZ87
CHEBI:17549
CHEMBL601
88755TAZ87
.delta.-aminolevulinic acid
4-oxo-5-amino-pentanoic acid
DTXSID8048490
5-azanyl-4-oxidanylidene-pentanoic acid
delta-aminolevulinate
Aminolevulinic
5-AMINOLEVULINIC ACID (MART.)
5-AMINOLEVULINIC ACID [MART.]
5-Aminolaevulinate
SMR000857229
Acid, Aminolevulinic
Delta Aminolevulinic Acid
Acid, Delta-Aminolevulinic
BF-200 ALA
FVT
5-aminolevulinic-acid
d-amino-levulinic acid
acido 5-aminolevulinico
Spectrum_001582
5-Amino-4-oxovalerate
SpecPlus_000858
Spectrum2_001662
Spectrum3_001654
Spectrum4_000618
Spectrum5_001505
5-amino-4-oxo-Pentanoate
SCHEMBL8243
BSPBio_003407
KBioGR_001176
KBioSS_002062
MLS001333097
MLS001333098
BIDD:GT0260
DivK1c_006954
SPBio_001843
GTPL4784
DTXCID4028464
KBio1_001898
KBio2_002062
KBio2_004630
KBio2_007198
KBio3_002627
GLXC-04438
HMS2231I19
HMS3259E22
HMS3369O14
AMINOLEVULINIC ACID [VANDF]
Levulinic acid, 5-amino- (8CI)
ALBB-023627
BCP23830
AC-054
AMINOLEVULINIC ACID [WHO-DD]
BDBM50240386
LMFA01100055
MFCD00044485
MSK167093
AKOS003587520
CS-W000450
DB00855
HY-W000450
NC00601
NCGC00178086-01
NCGC00178086-06
.DELTA.-AMINOLEVULINIC ACID [MI]
AS-30950
Pentanoic acid, 5-amino-4-oxo- (9CI)
SBI-0206721.P001
1ST167093
DB-040692
NS00001951
C00430
D07567
EN300-101562
AB00053763-07
AB00053763-08
AB00053763_09
AB00053763_10
Q238474
BRD-K57631554-003-06-2
BRD-K57631554-003-07-0
35BEC718-C970-426A-9859-BF58284C60B4
METHYLAMINOLEVULINATE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
203-414-1
Aminolevulinic Acid;ALA;5-Amino-4-oxopentanoic acid;5-amino-4-oxo-pentanoic acid;5-amino-4-keto-valeric acid