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Aminohydroxytriazolopyrimidine

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Identification
Molecular formula
C4H5N5O
CAS number
4233-33-4
IUPAC name
5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one
State
State

At room temperature, this compound exists as a solid. Triazolo derivatives are generally known for their stability in solid form making them easier to handle and store under ambient conditions.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.00
Boiling point (Celsius)
444.00
Boiling point (Kelvin)
717.00
General information
Molecular weight
153.12g/mol
Molar mass
153.1170g/mol
Density
1.8900g/cm3
Appearence

The compound appears as a white crystalline powder, which is common for many triazolo-based pyrimidines. Its structure confers a rigid and planar aspect typical of nitrogen heterocyclic compounds.

Comment on solubility

Solubility of 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one

The solubility of 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one can be characterized as follows:

  • Water Solubility: This compound exhibits moderate solubility in water, which can be attributed to the presence of amino and triazole functional groups that can interact favorably with water molecules.
  • Solvent Dependence: Solubility may vary significantly depending on the solvent used. Common polar solvents may enhance solubility, while nonpolar solvents tend to have poor interactions, leading to low solubility.
  • Temperature Influence: Increasing the temperature of the solvent usually increases solubility. As with many organic compounds, 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one may dissolve better at elevated temperatures.
  • pH Effects: Being an amino compound, the solubility may also be influenced by the pH of the solution. In more acidic or basic environments, the protonation or deprotonation of the amino group could enhance solubility.

In summary: The solubility of this compound is multifaceted and can be influenced by various factors including solvent type, temperature, and pH. Experimentation is often necessary to determine the best conditions for maximizing solubility.

Interesting facts

Interesting Facts about 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one

5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one is a fascinating organic compound that belongs to the category of heterocyclic compounds. Heterocycles are known for their diverse biological activities and applications in medicinal chemistry. Here are some noteworthy aspects of this particular compound:

  • Structural Significance: The structure of 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one features a combination of triazole and pyrimidine rings, which contribute to its unique chemical properties and reactivity.
  • Biological Activity: Compounds containing both triazole and pyrimidine motifs have been shown to possess various pharmacological activities, including antimicrobial, antiviral, and anticancer properties, making them promising candidates in drug discovery.
  • Synthesis Strategies: The synthesis of this compound can involve various methodologies such as cycloaddition reactions and functional group transformations, showcasing the creativity and versatility in organic synthesis.
  • Role in Research: This compound serves as a starting material or intermediate in the preparation of other more complex molecules, which has sparked interest among researchers aiming to develop new therapeutics.
  • Potential Applications: Due to its rich deck of functionalities, 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one is investigated for applications in medicinal chemistry, agrochemicals, and materials science.

As scientists continue to explore the multifaceted roles of heterocyclic compounds like 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one, it becomes increasingly evident that these compounds hold a treasure trove of potential awaiting discovery. Furthermore, as noted by many researchers, "the beauty of chemistry lies in the intricate relationships between structure and function." Embracing these connections paves the way for future innovations in the realms of health and technology.