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5-amino-1-phenylpyrazole-4-carboxamide

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Identification
Molecular formula
C10H10N4O
CAS number
869901-88-0
IUPAC name
5-amino-1-phenyl-pyrazole-4-carboxamide
State
State

At room temperature, 5-amino-1-phenylpyrazole-4-carboxamide is in a solid state. Its stability and crystalline nature make it suitable for use in various chemical syntheses and analytical applications.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
432.15
Boiling point (Kelvin)
705.30
General information
Molecular weight
202.21g/mol
Molar mass
202.2140g/mol
Density
1.3563g/cm3
Appearence

5-Amino-1-phenylpyrazole-4-carboxamide appears as a beige to light brown crystalline solid. It is not hygroscopic and is generally stable under ambient conditions. The compound is often used in its powder form for chemical research and synthesis purposes.

Comment on solubility

Solubility of 5-amino-1-phenyl-pyrazole-4-carboxamide

The solubility of a compound like 5-amino-1-phenyl-pyrazole-4-carboxamide (C10H10N4O) can vary significantly depending on several factors. Here are some key points to consider:

  • Solvent Polarity: Generally, compounds with polar functional groups tend to be more soluble in polar solvents, such as water. The presence of the carboxamide group contributes to this solubility.
  • Temperature Influence: Solubility often increases with temperature. Therefore, higher temperatures may enhance the dissolving process of this particular compound.
  • pH Level: The solubility of many organic compounds can change significantly with pH. The functional groups in 5-amino-1-phenyl-pyrazole-4-carboxamide can interact with protons, potentially affecting its overall solubility in various pH conditions.
  • Hydrogen Bonding: The ability of this compound to form hydrogen bonds can greatly affect its solubility. This means it may interact favorably with solvents that can also engage in hydrogen bonding.

It is important to note that while the predicted solubility is influenced by these factors, experimentations such as solubility tests in different solvents are essential for accurate data. Understanding the solubility behavior of 5-amino-1-phenyl-pyrazole-4-carboxamide can facilitate its proper application in various chemical processes.

Interesting facts

Interesting Facts about 5-Amino-1-phenyl-pyrazole-4-carboxamide

5-Amino-1-phenyl-pyrazole-4-carboxamide is a fascinating compound that belongs to the pyrazole family, which is known for its diverse range of biological activities. Here are some compelling points about this intriguing chemical:

  • Biological Activity: This compound is often studied for its potential pharmacological properties. It shows promise in various fields, particularly in medicinal chemistry for the development of novel drugs.
  • Diverse Applications: Pyrazole derivatives, including 5-amino-1-phenyl-pyrazole-4-carboxamide, are being explored for their use as anti-inflammatory, analgesic, and anticancer agents. The ability to modify the pyrazole ring allows chemists to tailor properties as needed.
  • Synthetic Versatility: The synthesis of this compound showcases a variety of methods. Researchers often utilize different reactions to incorporate functional groups, making it a versatile building block in organic synthesis.
  • Chemical Structure Insights: The unique arrangement of amino and carboxamide groups allows for interesting hydrogen bonding capabilities, which can influence the compound's stability and reactivity in biological systems.

As one delves deeper into the world of pyrazole compounds, it becomes evident that each derivative, including 5-amino-1-phenyl-pyrazole-4-carboxamide, contributes uniquely to our understanding of chemistry and potential therapeutic solutions. As noted by many researchers, "the key to unlocking new treatments can often be found in the smallest changes within a molecule."

In summary, 5-amino-1-phenyl-pyrazole-4-carboxamide stands as an example of how a simple alteration in molecular structure could yield significant advances in the realm of medicine and chemistry.

Synonyms
5-Amino-1-phenyl-1H-pyrazole-4-carboxamide
50427-77-5
5-Amino-1-phenylpyrazole-4-carboxamide
5-Amino-1-phenyl-4-pyrazolecarboxamide
MFCD00020732
CHEMBL4544218
NSC50566
Maybridge1_000861
ChemDiv2_000805
1H-Pyrazole-4-carboxamide, 5-amino-1-phenyl-
5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid amide
SCHEMBL2743084
HMS543P03
DTXSID90274334
HMS1371E13
NSC11602
BDBM50504979
NSC-11602
NSC-50566
STL020011
AKOS000345367
CCG-131303
FA17420
FB-0729
SDCCGMLS-0065430.P001
NSC 11602;NSC 50566
DB-071194
EU-0076114
EN300-16357
5-Amino-1-phenyl-1H-pyrazole-4-carboxamide #
AG-690/12868753
SR-01000474105
SR-01000474105-1
Z55410567
F0016-1629
F0863-0552
637-132-9
M2B