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Adenylic acid

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
5-amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]imidazole-4-carboxylic acid
State
State

At room temperature, adenylic acid is typically in a solid state, often as a crystalline powder due to its stability and composition. It remains stable under standard laboratory conditions and is commonly stored as a dry powder for various biochemical applications.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
117.00
Boiling point (Kelvin)
390.15
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
1.3300g/cm3
Appearence

Adenylic acid, also known as AMP or 5'-adenylic acid, appears as a white crystalline compound when isolated in its pure form. It is typically a powder and is highly soluble in water. Due to its role in biochemistry and molecular biology, this compound is often used in a crystalline or powdered form in laboratories.

Comment on solubility

Solubility of 5-amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]imidazole-4-carboxylic acid

The solubility of 5-amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]imidazole-4-carboxylic acid (C10H14N5O7P) is influenced by its complex structure and functional groups. This compound contains both amino and carboxylic acid functionalities, indicating potential solubility in polar solvents such as water. The presence of phosphate and hydroxyl groups also enhances its ability to interact through hydrogen bonding, contributing to solvation in aqueous solutions.

Key Factors Influencing Solubility:

  • Polarity: The polar nature of the groups present facilitates dissolution in water.
  • Hydrogen Bonding: The molecular structure enables significant hydrogen bonding, which aids in solubility.
  • pH Dependency: As an acid, its solubility may vary with pH, particularly in acidic or basic environments.

In conclusion, while this compound shows potential for enhanced solubility in water due to its functional groups, actual solubility testing is essential to determine its practical applications in various fields. Such tests will provide crucial insights into its behavior in biological systems and industrial applications.

Interesting facts

Interesting Facts about 5-Amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]imidazole-4-carboxylic Acid

This compound, often referenced in the context of biochemical research, has generated interest due to its multifunctional properties and potential applications. Here are some fascinating points to consider:

  • Biochemical Significance: The presence of both amino and carboxylic acid functional groups means this compound can participate in a variety of biochemical pathways, making it a vital player in biological systems.
  • Phosphonate Group: The phosphonooxymethyl group enhances the molecule's ability to interact with biological targets. Phosphonates are notably important in drug design due to their role in biological systems, such as influencing enzyme activity.
  • Regulatory Role: Compounds like this one can act as intermediates in the synthesis of nucleotides and nucleic acids, which are essential for life. They may be involved in processes such as cell signaling and energy transfer.
  • Potential Therapeutic Applications: Researchers are looking at similar compounds for applications in treating various diseases, including viral infections and cancers. Their unique structure allows them to occupy active sites on enzymes, potentially inhibiting undesirable biological activity.
  • Structure-Activity Relationship: The complex structure of this compound allows for intensive study into how modifications can affect its biological activity. Understanding these relationships can lead to the development of more effective pharmaceuticals.

This compound serves as a remarkable example of how intricate changes to molecular structure can lead to significant effects in biological functionality, making it a compelling subject for ongoing scientific investigation.

Synonyms
5-phosphoribosyl-4-carboxy-5-aminoimidazole
5-amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]imidazole-4-carboxylic acid
CAIR; 4-Carboxy-AIR
CHEBI:185031
AICA ribonucleotide, (D-ribofuranosyl)-isomer
5-Aminoimidazole-4-carboxylic acid-1-b-D-ribofuranose 5'-monophosphate