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Primidone

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Identification
Molecular formula
C12H14N2O2
CAS number
125-33-7
IUPAC name
5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione
State
State
Primidone is typically in a solid state at room temperature, existing as a crystalline powder.
Melting point (Celsius)
279.00
Melting point (Kelvin)
552.00
Boiling point (Celsius)
405.15
Boiling point (Kelvin)
678.30
General information
Molecular weight
218.26g/mol
Molar mass
218.2510g/mol
Density
1.2000g/cm3
Appearence

Primidone is typically a white or almost white crystalline powder. It may have no distinct odor and is known for its stable nature under ordinary conditions.

Comment on solubility

Solubility of 5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione is an intriguing aspect of its chemical behavior. As a compound with a complex structure, its solubility can vary significantly depending on several factors:

  • Polarity: The presence of various functional groups in the structure influences polarity, affecting how well the compound dissolves in polar or non-polar solvents.
  • Solvent Interaction: The ability of 5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione to dissolve in common solvents such as water, ethanol, or organic solvents is crucial. The compatibility with these solvents can dictate its applications in chemical processes.
  • Temperature Effects: Temperature can play a significant role in solubility; typically, an increase in temperature enhances the solubility of many compounds, although this may not hold true for all.
  • Concentration: The concentration of the compound in solution can also affect its solubility, with higher concentrations sometimes leading to saturation where no further dissolution occurs.

Thus, understanding the solubility of this compound requires careful consideration of these factors. As the saying goes, "solubility is a window into chemical reactivity," making it a critical point of exploration in its study and applications.

Interesting facts

Interesting Facts about 5-Allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione

5-Allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound that belongs to the family of pyrimidine derivatives. This compound is notable for its complex structure and unique chemical properties. Here are some interesting insights:

  • Versatile Precursor: Due to its unique chemical structure, this compound serves as a versatile precursor in organic synthesis. It can be transformed into various useful derivatives, which makes it valuable in the laboratory.
  • Biological Significance: Some derivatives of pyrimidine compounds are known for their biological activity. This opens up possibilities for research into pharmaceuticals, particularly in the fields of antiviral and anticancer treatments.
  • Reactivity and Stability: The presence of multiple functional groups within this compound contributes to its reactivity. This prompts interesting studies on how it may undergo transformations under different conditions, revealing insights about reaction mechanisms.
  • Modern Applications: As researchers explore the properties of nitrogen-containing heterocycles, compounds like 5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione gain attention for their potential within advanced materials or as catalysts in organic reactions.
  • Structure-Activity Relationship (SAR): The structural nuances of this compound allow it to play a critical role in SAR studies, helping chemists understand how molecular modifications affect biological activity and chemical reactivity.

In summary, 5-allyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione is not just a simple compound; it encapsulates the rich interplay of structure, reactivity, and potential applications in both fundamental research and pharmaceutical development.

Synonyms
APROBARBITAL
Allypropymal
Alurate
Allylpropymal
Aprobarbitone
Allonal
Allional
Aprobarbita
Aprozal
Numal
77-02-1
Allylisopropylmalonylurea
5-Allyl-5-isopropylbarbituric acid
Alurate elixir verdum
Allypropymalum
Allylisopropylbarbituric acid
Isopropylallylbarbituric acid
5-Isopropyl-5-allylbarbituric acid
Isonal (swedish)
Aprobarbitale
Aprobarbitalum
5-Allyl-5-isopropylbarbiturate
Aprobarbitale [DCIT]
Aprobarbitalum [INN-Latin]
Barbituric acid, 5-allyl-5-isopropyl-
Alurate (TN)
Aprobarbital (INN)
CCRIS 7088
NSC 120769
HSDB 3290
UNII-Q0YKG9L6RF
EINECS 200-997-4
5-(1-Methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Aprobarbital [INN:DCF:NF]
NSC-120769
BRN 0180858
CHEBI:2791
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-
5-allyl-5-isopropylpyrimidine-2,4,6(1H,3H,5H)-trione
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
APROBARBITAL [MI]
NSC120769
Q0YKG9L6RF
APROBARBITAL [INN]
APROBARBITAL [HSDB]
APROBARBITAL [VANDF]
APROBARBITAL [MART.]
APROBARBITAL [WHO-DD]
DTXSID8022616
5-24-09-00224 (Beilstein Handbook Reference)
5-(prop-2-en-1-yl)-5-(propan-2-yl)-1,3-diazinane-2,4,6-trione
5-(propan-2-yl)-5-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
Aprobarbitalum (INN-Latin)
APROBARBITAL (MART.)
5-Allyl-5-isopropyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Aprobarbital (1.0 mg/ml in Methanol)
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)- (9CI)
CHEMBL7863
SCHEMBL78101
DTXCID102616
SCHEMBL15364625
SCHEMBL22556213
N05CA05
HY-U00166
5-(1-methylethyl)-5-prop-2-en-1-ylpyrimidine-2,4,6(1H,3H,5H)-trione
AKOS003404772
CS-7223
DB01352
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-(9CI)
WLN: T6VMVMV FHJ FY1&1 F2U1
NS00005163
C07826
D00698
Q411940
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-allyl-5-isopropyl-
2,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-
5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H, 3H, 5H)-pyrimidinetrione
200-997-4