Skip to main content

Neomycin B

ADVERTISEMENT
Identification
Molecular formula
C23H46N6O13
CAS number
119-04-0
IUPAC name
5-acetamido-2-[5-[3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-2-[6-(2-amino-3-hydroxy-octadec-4-enoxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid
State
State

At room temperature, Neomycin B is in a solid state. It is generally available as a sulfate salt which is soluble in water due to its hydrophilic properties.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
614.63g/mol
Molar mass
614.6340g/mol
Density
1.4456g/cm3
Appearence

Neomycin B typically appears as white to off-white crystalline powder. It is known for being hygroscopic, which means it can absorb moisture from the environment easily.

Comment on solubility

Solubility of 5-acetamido-2-[5-[3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-2-[6-(2-amino-3-hydroxy-octadec-4-enoxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

This compound, with the chemical formula C23H46N6O13, exhibits intricate solubility characteristics due to its complex molecular structure. The presence of multiple hydroxyl groups and various functional groups enhances its potential for solubility in polar solvents.

Factors influencing solubility:

  • Hydroxyl Groups: Multiple -OH groups facilitate hydrogen bonding, which generally increases solubility in water.
  • Hydrophobic Regions: Portions of the molecule may contain hydrophobic (non-polar) regions, which could limit solubility in highly polar solvents.
  • Molecular Size: The larger molecular structure may affect overall solubility, possibly necessitating the use of enhanced solubilizing techniques.

In conclusion, while this compound may show good solubility in polar solvents such as water due to its extensive hydrogen-bonding capabilities, it is important to consider other factors that could influence its solubility in various environments. The interplay between hydrophilic and hydrophobic characteristics creates a complex solubility profile that can be further studied through experimental methods.

Interesting facts

Interesting Facts about 5-Acetamido-2-[5-[3-Acetamido-5-Hydroxy-6-(Hydroxymethyl)-4-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl]Oxy-Tetrahydropyran-2-Yl]Oxy-2-[6-(2-Amino-3-Hydroxy-Octadec-4-Enoxy)-4,5-Dihydroxy-2-(Hydroxymethyl)Tetrahydropyran-3-Yl]Oxy-3-Hydroxy-6-(Hydroxymethyl)Tetrahydropyran-4-Yl]Oxy-4-Hydroxy-6-(1,2,3-Trihydroxypropyl)Tetrahydropyran-2-Carboxylic Acid

This complex compound is a marvel of structural chemistry, characterized by a series of intricate tetrahydropyran rings and numerous hydroxyl (-OH) groups that contribute to its distinctive chemical behavior and potential applications. Here are some fascinating insights:

  • Multifunctionality: The presence of multiple functional groups—including hydroxyls, amino, and acetamido groups—suggests a potential for varied biological activity. Such diversity can allow for interactions in biochemical pathways.
  • Biological Importance: Many compounds with similar structural motifs are known to play crucial roles in biological systems. They can potentially act as therapeutic agents, especially in areas related to carbohydrate metabolism and cell signaling.
  • Natural Analogues: This compound's structure exhibits resemblance to naturally occurring oligosaccharides and polysaccharides, which are integral in cellular processes. This resemblance begs the question of its source and how it can be synthesized or extracted.
  • Research Applications: Due to its sophisticated architecture, scientists might explore this compound in fields such as medicinal chemistry, pharmacology, and polymer science, examining its efficacy as a drug or as a building block in newer materials.

As we continue to unravel its structural complexities, this compound illustrates the profound connection between structure and function in chemistry and biology, challenging us to explore its full potential in scientific research.

Synonyms
PD077134