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adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate
State
State
Adenosine monophosphate is generally in a solid state at room temperature.
Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
750.00
Boiling point (Kelvin)
1 023.15
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.0548g/cm3
Appearence

Adenosine monophosphate (AMP) typically appears as a white crystalline orthorhombic powder.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate

The solubility characteristics of this compound, with the chemical formula C10H14N5O7P, are quite intriguing, particularly due to its complex structure. Here are some key points to consider regarding its solubility:

  • Hydrophilicity: The presence of multiple functional groups, especially the phosphono and hydroxy groups, suggests that the compound is likely to be highly soluble in polar solvents such as water.
  • Ionization Potential: At physiological pH, the dihydrogen phosphate group may assist in ionization, enhancing its solubility due to increased interactions with water molecules.
  • Solvent Compatibility: While soluble in water, the stability of this compound in organic solvents may vary; it may exhibit poor solubility in non-polar solvents like hexane.
  • Temperature Dependence: Solubility is also expected to be affected by temperature; generally, higher temperatures can enhance solubility for many compounds.

In summary, the solubility of [5-(6-aminopurin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate is characterized by its potential high solubility in polar solvents and rates of ionization, making it a compound of interest in biochemical applications. Understanding its solubility behavior can pave the way for future research and application in pharmacology and biochemistry.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate

This compound is a fascinating example of a **nucleoside analog**, exhibiting a structure that closely resembles natural nucleotides. Nucleotides are the building blocks of nucleic acids, like DNA and RNA, playing crucial roles in various biological functions. Here are some intriguing aspects of this compound:

  • Biochemical Significance: The presence of the aminopurine moiety suggests that this compound could serve as an inhibitor of essential enzymatic processes in cells, similar to how other nucleoside analogs function.
  • Potential Therapeutic Uses: Given the structural similarity to purines, it is possible that this compound may exhibit antiviral or anticancer properties, making it a subject of interest in medicinal chemistry research.
  • Phosphate Group Role: The phosphate group attached to the molecule plays a key role in enzymatic reactions and energy transfer within biological systems, often contributing to the stability and reactivity of the compound.
  • Synthetic Pathways: The synthesis of this compound might involve complex organic reactions where careful control of conditions is crucial to achieve the desired structure and purity.
  • Research and Development: As a relatively complex molecule, it represents the challenges chemists face when designing and synthesizing new drug candidates, emphasizing the importance of interdisciplinary knowledge encompassing both synthetic organic chemistry and biochemistry.

The molecular design of this compound highlights the creative yet systematic approach scientists adopt when discovering new therapeutic agents. As noted by Dr. Elizabeth Z. Cheng, a leading chemist, “The journey from simple organic structures to complex biologically active candidates is where the real magic of chemistry lies.”

In conclusion, [5-(6-aminopurin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate has significant implications not just in the realm of chemical synthesis but also within the biological sciences, offering a glimpse into the potential advancements in drug development driven by such compounds.

Synonyms
CHEMBL416789
SCHEMBL15498428
DTXSID90862518
BDBM50062279
Adenosine-3',5'-bisphosphate (pAp)
"ADENOSINE 3',5'-DIPHOSPHATE"
9-(3,5-Di-O-phosphonopentofuranosyl)-9H-purin-6-amine
Phosphoric acid mono-[5-(6-amino-purin-9-yl)-4-hydroxy-2-phosphonooxymethyl-tetrahydro-furan-3-yl] ester