Skip to main content

Adenosine monophosphate (AMP)

ADVERTISEMENT
Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl sulfo hydrogen phosphate
State
State

At room temperature, adenosine monophosphate is typically found as a solid.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.2000g/cm3
Appearence

Adenosine monophosphate, commonly known as AMP, typically appears as a white crystalline powder. It can also be found in solution form as a part of many biological processes.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl sulfo hydrogen phosphate

The solubility characteristics of the compound [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl sulfo hydrogen phosphate, with the chemical formula C10H14N5O7P, reveal important insights into its potential applications and interactions.

Solubility Insights:

  • Hydrophilicity: The presence of multiple hydroxyl groups (-OH) in the structure significantly enhances its hydrophilicity, suggesting good solubility in polar solvents such as water.
  • Ionization Potential: Given the phosphate functional group, the compound is likely to ionize in aqueous solutions, which can further increase its solubility due to enhanced solvate interactions.
  • Temperature Dependence: As with many compounds, solubility may vary with temperature. Typically, an increase in temperature can result in higher solubility for many solids in liquids.
  • pH Sensitivity: The solubility may also be influenced by pH; changes in the hydrogen ion concentration can affect both the ionization of the phosphate group and the overall charge of the molecule, leading to variations in solubility.

In summary, the solubility profile of this complex compound is dictated by its functional groups, ionizable nature, and environmental conditions. Understanding these factors is crucial for its practical use in biochemical applications as well as in pharmaceutical formulations.

Interesting facts

Interesting Facts About [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl sulfo hydrogen phosphate

This intriguing compound is a derivative of purine, a critical building block of nucleic acids. It combines a purine base with a unique tetrahydrofuran sugar structure, which plays a vital role in biochemical processes.

Key Features

  • Role in Biochemistry: Compounds like this are essential in various biochemical pathways, particularly in relation to nucleic acid metabolism.
  • Potential Therapeutic Applications: The compound holds promise in pharmaceutical formulations, potentially contributing to the development of antiviral or anticancer agents.
  • Structural Complexity: The presence of the sulfo hydrogen phosphate group adds an additional layer of functionality, making it a subject of interest in drug design.

According to famous biochemist Arthur Kornberg, “The enzyme is a very amazing thing; it carries out its catalytic action with exquisite specificity.” This statement resonates with the intricate nature of compounds such as this one, which can interact with specific enzymes in the body to elicit desired biological reactions.

Chemical Interactions

The functionality of this compound allows it to participate in many chemical interactions, including:

  • Hydrogen bonding, which can influence its stability and reactivity.
  • Electrostatic interactions with other biomolecules, enhancing its biological activity.
  • Hydrophobic interactions, affecting its solubility and transport mechanisms within biological systems.

In summary, this compound exemplifies the beauty and complexity of chemical structures found in nature, showcasing how specific arrangements of atoms can lead to significant biological effects and therapeutic potential.

Synonyms
9-{5-O-[Hydroxy(sulfooxy)phosphoryl]pentofuranosyl}-9H-purin-6-amine
[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl sulfo hydrogen phosphate
9-(5-O-(Hydroxy(sulfooxy)phosphoryl)pentofuranosyl)-9H-purin-6-amine
(5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl sulfo hydrogen phosphate
SCHEMBL4292820
SCHEMBL20277489
DTXSID90862013
BDBM526193
US11185100, TABLE 7.7
6-AMINO-9-[3,4-DIHYDROXY-5-[(HYDROXY-SULFOOXY-PHOSPHORYL)OXYMETHYL]OXOLAN-2-YL]-PURINE