Skip to main content

Acyclovir

ADVERTISEMENT
Identification
Molecular formula
C8H11N5O3
CAS number
59277-89-3
IUPAC name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl N-(2,5-diamino-5-oxo-pentanoyl)sulfamate
State
State

At room temperature, Acyclovir is a solid. It exists stably as a crystalline substance and is typically used in this form in pharmaceutical applications.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
372.50
Boiling point (Kelvin)
645.60
General information
Molecular weight
225.21g/mol
Molar mass
225.2060g/mol
Density
1.2000g/cm3
Appearence

Acyclovir typically appears as a white to off-white crystalline powder. It is odorless and may appear as either fine powder or small crystals, depending on the preparation method.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl N-(2,5-diamino-5-oxo-pentanoyl)sulfamate

The compound with the chemical formula C8H11N5O3 exhibits intriguing solubility properties that are pivotal for its functionality in various applications.

General Solubility Characteristics

When discussing the solubility of this compound, several factors come into play:

  • Polarity: The presence of multiple functional groups, such as amino and hydroxyl groups, enhances its polarity, which typically suggests increased solubility in polar solvents.
  • Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding further supports its solubility profile, allowing it to dissolve in aqueous solutions.
  • Conditions: Solubility may vary significantly with changes in pH and temperature, as the ionization of amino groups plays a critical role.

Solvent Interactions

This compound is expected to be:

  • More soluble in water than in nonpolar organic solvents due to its hydrophilic character.
  • Soluble in common alcohols or dimethyl sulfoxide (DMSO), which can stabilize ionic interactions.

In conclusion, understanding the solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl N-(2,5-diamino-5-oxo-pentanoyl)sulfamate is crucial for its effective application in biochemical contexts. Knowledge of its solubility behavior helps researchers and practitioners anticipate interactions with biological systems and design appropriate formulations.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl N-(2,5-diamino-5-oxo-pentanoyl)sulfamate

This compound, a complex molecule featuring a purine base, is noteworthy for its structural and functional characteristics. It combines a range of functional groups that may impart it with unique biological activities.

Key Features:

  • Purine Derivative: The presence of a purine moiety (6-aminopurine) suggests potential roles in nucleic acid interactions, affecting DNA and RNA processes.
  • Hydroxyl Groups: The dihydroxy functional groups may enhance solubility and reactivity, possibly influencing its biological effect.
  • Sulfamate Group: This group is known to have applications in medicinal chemistry, particularly in drugs targeting certain enzymes and pathways.

Studying this compound can unlock valuable insights into:

  • Its potential as a therapeutic agent, especially given its structural resemblance to critical biological molecules.
  • The mechanisms through which it interacts with biological targets, possibly leading to innovative treatments in medicine.

As with many complex organic compounds, the balance between structure and function is crucial. Escaping the simplicity of chemical formulas, this molecule embodies a rich diversity of applications and underscores the beauty of organic chemistry. Researchers often quote, "The structure of a molecule offers insight into its function.", making it imperative to analyze such intricate compounds further. This combination of scientific exploration and chemical innovation continues to inspire students and chemists alike!

Synonyms
JIA54357