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Adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dimethylamino hydrogen phosphate
State
State

At room temperature, adenosine monophosphate is typically found as a solid.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
1.3600g/cm3
Appearence

Adenosine monophosphate typically appears as a white to off-white crystalline powder. It is generally odorless and has a somewhat bitter taste.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dimethylamino hydrogen phosphate

The solubility of the compound [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dimethylamino hydrogen phosphate (C10H14N5O7P) is an intricate subject due to the presence of various functional groups. Here are some key points regarding its solubility:

  • Hydrophilicity: The compound features multiple hydroxyl groups (-OH) which generally enhance solubility in polar solvents, especially water.
  • Amine Group: The presence of the amine functional group provides additional sites for hydrogen bonding, further increasing its aqueous solubility.
  • Phosphate Group: The phosphate moiety is known for its high solubility in water, making the compound likely to dissolve well in polar environments.
  • Overall Polar Character: Given the combination of functional groups present, we can infer that this compound likely exhibits a significant degree of polar character.

However, solubility can be influenced by various factors:

  • Solution pH: The pH of the environment can alter the ionization of the amine and phosphate groups, affecting solubility.
  • Temperature: Increasing temperature typically enhances solubility for most compounds, but specific behaviors can vary.
  • Concentration: In highly concentrated solutions, solubility may decrease due to saturation effects.

In conclusion, it would be reasonable to expect that this compound demonstrates good solubility in water and possibly in other polar solvents, making it potentially useful for various biochemical applications.

Interesting facts

Interesting Facts about [5-(6-Aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dimethylamino hydrogen phosphate

This compound is a fascinating example of a nucleotide analog and plays a significant role in molecular biology and medicinal chemistry. Here are some intriguing aspects of its structure and function:

  • Nucleotide Analog: The compound features a purine base, specifically 6-aminopurine, which is a derivative of adenine. This resemblance allows it to mimic natural nucleotides, making it valuable in studying nucleic acid interactions.
  • Potential Applications: Researchers often explore compounds like this for their potential in drug development, particularly in treating viral infections or cancer, due to their ability to interfere with nucleic acid synthesis.
  • Hydrogen Phosphate Group: The presence of a hydrogen phosphate moiety enhances its polarity and solubility, contributing to its bioactivity, particularly in biological systems where phosphate groups are essential.
  • Unique Tetrahydrofuran Structure: The tetrahydrofuran ring adds an interesting layer to the compound's framework, potentially affecting its pharmacokinetics—how it is absorbed, distributed, metabolized, and excreted in living organisms.

As one prominent scientist noted, "The modification of nucleotide structures opens a treasure trove of possibilities for therapeutic innovations." This compound, with its complex architecture and biological significance, is a remarkable testament to the versatility of chemical compounds in biochemistry.

In summary, [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dimethylamino hydrogen phosphate serves as an essential reminder that even the intricacies of molecular structure can lead to groundbreaking advancements in health and science.