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Adenosine monophosphate (AMP)

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

Solid at room temperature.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.8000g/cm3
Appearence

Adenosine monophosphate typically appears as a white crystalline powder. It is generally odorless.

Comment on solubility

Solubility Characteristics of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The compound [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate, with the chemical formula C10H14N5O7P, demonstrates intriguing solubility properties:

  • Polar Nature: Due to the presence of multiple hydroxyl (-OH) and phosphate groups, this compound is likely to be highly polar, influencing its solubility in water.
  • Hydrophilicity: The compound's structural features, including amino and hydroxyl functional groups, suggest a tendency to engage in hydrogen bonding with water molecules.
  • Solubility Profile: Expect significant solubility in polar solvents, particularly in aqueous environments, making it useful in biochemical applications where water solubility is essential.

In conclusion, the solubility of this compound can be attributed to its polar functional groups, which enhance interactions with water, thus facilitating its dissolution. As such, it plays a critical role in its efficacy and application in various chemical and biological contexts.

Interesting facts

Interesting Facts about [5-(6-Aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This remarkable compound is a fascinating blend of organic and biological chemistry, featuring a unique structure that makes it noteworthy in several fields of research.

Biological Significance

  • Nucleotide Analogs: Its resemblance to nucleotides opens up significant avenues in genetic research and therapeutics.
  • RNA Interactions: Being structurally related to purines, it may have roles in RNA interactions, influencing cellular processes.
  • Drug Development: Researchers explore its applications in developing medications targeting various diseases, including cancer.

Chemical Properties

As a dihydrogen phosphate, it possesses intriguing chemical properties that enable it to participate in various biochemical reactions, particularly in phosphorylation processes. This can be vital for energy transfer within cells.

Potential Applications

  • Biochemistry Research: Ideal for studying nucleophiles or electrophiles within biological systems.
  • Antiviral Strategies: Its structural characteristics might be leveraged to disrupt viral replication mechanisms.
  • Enzyme Inhibition: Potential use in investigating enzyme interactions, particularly those involved in nucleotide metabolism.

Overall, this compound is a prime example of how intricate and fascinating the world of chemical compounds can be, especially when they overlap with biological functions and medical applications. As one scientist aptly put it, "The intersections of chemistry and biology hold the keys to unlock the mysteries of life itself."

Synonyms
9-(5-O-phosphonopentofuranosyl)-9H-purin-6-amine
[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
31077-38-0
NSC20264
Vidarabine (phosphate)
122768-03-0
NSC127223
67583-85-1
Ara-A (phosphate);Adenine Arabinoside (phosphate);9-beta-D-Arabinofuranosyladenine (phosphate)
Vidarabine5'-monophosphate
9H-Purine, 5'-phosphate
9H-Purin-6-amine,9-(5-O-phosphono-b-D-arabinofuranosyl)-
ADENYLIC ACID, YEAST
CHEMBL16720
SCHEMBL144997
SCHEMBL20277555
CHEBI:181501
XEA76803
Adenine, 5'-(dihydrogen phosphate)
BBL033984
NSC257884
STL372938
AKOS025248003
NSC-257884
Adenosine 5\'-monophosphate monohydrate
NCGC00094831-01
NCGC00094831-02
NCGC00094831-03
NCI60_002075
SY035647
5 inverted exclamation mark -Adenylic Acid
NS00013345
9-.beta.-D-Arabinofuranosyladenine 5'-phosphate
9-.beta.-D-Arabinofuranosyladenine monophosphate
Adenine-9-b-D-arabinofuranoside-5'-monophosphate
L001143
9-.beta.-D-Arabinofuranosyladenine 5'-monophosphate
WLN: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQQO
9-(.beta.-D-Arabinofuranosyl)adenine 5'-(dihydrogen phosphate)
9-(5-O-Phosphono-.beta.-D-arabinofuranosyl)-9H-purin-6-amine
[5-(6-Aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic aci d