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S-Adenosylmethionine

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Identification
Molecular formula
C15H22N6O5S
CAS number
29908-03-0
IUPAC name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl-(3-carboxy-3-oxo-propyl)-methyl-sulfonium
State
State

At room temperature, S-Adenosylmethionine is typically in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
398.44g/mol
Molar mass
398.4410g/mol
Density
1.2800g/cm3
Appearence

S-Adenosylmethionine (SAMe) is typically isolated as its crystalline form. It appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl-(3-carboxy-3-oxo-propyl)-methyl-sulfonium

The solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl-(3-carboxy-3-oxo-propyl)-methyl-sulfonium (C15H22N6O5S) is a key aspect of its chemical properties and potential applications. Understanding its solubility can provide insight into its behavior in different solvents and environments. Here are some points to consider:

  • Polar vs. Non-Polar Solvents: Given the presence of multiple functional groups such as sulfonium and carboxylic acid, the compound is expected to be more soluble in polar solvents like water and ethanol.
  • Ionic Character: The sulfonium group may impart some ionic properties, enhancing solubility in aqueous solutions.
  • Hydrophilicity: The -OH (hydroxyl) groups contribute to hydrophilicity, likely boosting solubility in water.
  • Concentration Influences: Solubility may vary with concentration; therefore, it's important to consider the saturated concentration when assessing practical applications.

As with many organic compounds, the solubility can significantly affect reactivity and bioavailability, making it essential to conduct solubility tests under varying conditions to fully understand this compound's behavior in solution.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl-(3-carboxy-3-oxo-propyl)-methyl-sulfonium

This compound, with its complex structure, represents an intriguing intersection of biochemistry and medicinal chemistry. Here are some noteworthy aspects:

  • Pharmacological Potential: The presence of the aminopurine moiety suggests potential applications in nucleic acid chemistry and as a building block for nucleotide analogs, which could be significant in the development of antiviral and anticancer therapies.
  • Functional Groups: The molecule contains several functional groups, including a carboxylic acid and a sulfonium ion. These groups are known to enhance solubility and reactivity, potentially making the compound a valuable candidate for drug development.
  • Bioactivity: Compounds that incorporate purine derivatives often exhibit bioactivity. This specific structure may influence biomolecular interactions, particularly in enzyme inhibition studies or as a ligand for various biomolecules.
  • Structure-Activity Relationships: The intricate arrangement of functional groups opens avenues for exploring structure-activity relationships (SAR). Understanding how modifications impact bioactivity can lead to more effective and specific therapeutic agents.
  • Research Applications: Potentially serves as a model for synthesizing other sulfonium-containing compounds, making it an interesting subject for synthetic organic chemists aiming to create new compounds for interdisciplinary applications.

As a chemistry student, studying compounds like this offers valuable insights into the synthesis and functionality of complex organic molecules, paving the way for innovations in pharmaceuticals and biochemistry. It illustrates the beauty of chemistry, where intricate structures hold the key to unlocking new therapeutic potentials!