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Nicotinamide adenine dinucleotide

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Identification
Molecular formula
C21H27N7O14P2
CAS number
53-84-9
IUPAC name
[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-[3-carbamoyl-4-(1-methyl-2-oxo-butyl)pyridin-1-ium-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
State
State

At room temperature, nicotinamide adenine dinucleotide is typically found as a solid powder. It is often handled in laboratory and industrial settings in its salt forms, which can dissolve in water, forming colorless solutions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
663.43g/mol
Molar mass
663.4250g/mol
Density
0.9543g/cm3
Appearence

Nicotinamide adenine dinucleotide typically appears as a white amorphous powder. When isolated, it is often in the form of crystalline salts. It is hygroscopic, meaning it can absorb moisture from the air. In solution, it is colorless and can exhibit fluorescence under specific conditions.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-[3-carbamoyl-4-(1-methyl-2-oxo-butyl)pyridin-1-ium-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

The solubility of this compound, with the formula C21H27N7O14P2, can be quite complex due to its unique structure and functional groups. Understanding solubility involves considering various factors:

  • Polar vs. Non-polar Characteristics: The presence of multiple hydroxyl (-OH) groups as well as phosphate (-PO4) groups suggests a tendency towards high polarity, which generally enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the hydroxyl and phosphate groups to participate in hydrogen bonding plays a critical role in solubility. These interactions can lead to a favorable solubility environment in aqueous solutions.
  • Ionic Interactions: The presence of a pyridinium ion in the structure indicates potential ionic solubility enhancement, particularly in polar solvents, further promoting solubility.

Given these structural elements, one could anticipate that this compound may exhibit moderate to high solubility in water. However, solubility can vary significantly based on the concentration of the solution, temperature, and the presence of other solutes.

Understanding the solubility properties of such complex compounds is essential, especially for applications in pharmaceuticals and biochemistry, where bioavailability is crucial.

Interesting facts

Interesting Facts About the Compound

The compound name may sound complicated, but it's a fascinating molecule with a rich background, particularly in the realms of biochemistry and pharmacology. Here are some enlightening facts about this compound:

  • Biological Significance: This compound is an important derivative of nucleotides, which are the building blocks of nucleic acids like DNA and RNA. Its structure suggests potential roles in various biochemical pathways, especially in cellular signaling.
  • Structural Complexity: Featuring a complex framework incorporating several functional groups, including a phosphoryl group, this compound showcases the intricate nature of organic molecules and their potential functionalities.
  • Pharmacological Potential: Molecules similar to this compound have been investigated for their potential therapeutic effects. Compounds that enhance nucleotide metabolism may find applications in treating metabolic disorders and cancer.
  • Unique Features: The inclusion of functional groups such as amines and pyridines can result in interesting interactions with biological molecules, potentially leading to innovative drug designs.
  • Chemical Versatility: The presence of both hydroxy and carbamoyl groups suggests that the compound has versatile reactivity, allowing it to participate in a variety of chemical reactions, which is crucial for synthetic organic chemistry.

As a scientist or chemistry student, exploring the nuances of such complex compounds can unravel a wide array of potential applications in medicine and biochemistry. The study of similar structures paves the way for breakthroughs in our understanding of molecular interactions and biological processes.