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Adenosine 5'-phosphosalicylate

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Identification
Molecular formula
C16H19N5O9P
CAS number
83778-12-7
IUPAC name
[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] 2,3-dihydroxybenzoate
State
State

At room temperature, Adenosine 5'-phosphosalicylate is typically found as a solid, owing to its complex and stable molecular structure.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
467.27g/mol
Molar mass
467.2650g/mol
Density
1.8500g/cm3
Appearence

Adenosine 5'-phosphosalicylate, being a complex organic molecule, does not have a common description of appearance due to its specific use in biochemical research.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl 2,3-dihydroxybenzoate

The compound C16H19N5O9P exhibits intriguing solubility characteristics influenced by its complex molecular structure and functional groups. Solubility is a crucial property in various applications, particularly in pharmaceuticals, where the bioavailability of compounds is essential. Here are some noteworthy aspects regarding its solubility:

  • Functional Groups: The presence of hydroxyl (-OH) groups tends to enhance solubility in polar solvents such as water due to hydrogen bonding.
  • Overall Polarity: The combination of different functional groups creates a polar molecule, which generally increases water solubility.
  • pH Dependence: The solubility can change with pH, especially for compounds with ionizable groups, such as carboxylates or amines.
  • Solvent Interaction: In organic solvents, this compound may exhibit different solubility depending on the solvent's polarity.
  • Complexation: Interactions with metal ions may also affect solubility, potentially forming soluble complexes.

In conclusion, while the specific solubility data for this compound may vary based on conditions, its structural components suggest a favorable profile for solubility in a range of solvents, making it an interesting candidate for further exploration in solubility studies.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl 2,3-dihydroxybenzoate

This compound is a fascinating example of the intersection of nucleic acid chemistry and phosphate ester chemistry. It integrates components that are pivotal for biological processes, specifically the complex structures that mimic or aid the function of nucleotides.

Key Features

  • Structure: The molecule contains a purine base derivative, which is essential in the formation of nucleotides, and a sugar-like component that resembles ribose. This structural mimicry is critical for modulatory functions in nucleic acid biochemistry.
  • Biological Significance: Compounds of this nature have been studied for their roles in signal transduction and as potential therapeutic agents in the treatment of various diseases, including cancer and viral infections.
  • Research Potential: As scientists continue to explore the properties of compounds that influence cellular pathways, this compound's unique conformation presents an opportunity to develop new drug candidates that can effectively target specific biological interactions.

Applications and Studies

Recent studies have shown that derivatives like this compound can significantly impact therapeutic strategies. For example:

  • They may enhance drug delivery systems through their phosphonate esters, allowing for more targeted treatment.
  • The dihydroxybenzoate moiety shows promise in enhancing bioavailability, making it an attractive area of research in pharmacology.

In conclusion, [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl 2,3-dihydroxybenzoate exemplifies the intricate design of biochemical compounds that can influence cellular mechanisms and open new avenues for therapeutic intervention. The ongoing exploration of its properties could lead to substantial advancements in both chemistry and medicine.