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Adenosine monophosphate (AMP)

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate
State
State

Adenosine monophosphate is typically found in its solid state at room temperature. It is a component of nucleic acids and biochemical processes, such as cellular energy transfer.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
1.6000g/cm3
Appearence

Adenosine monophosphate typically appears as a white or off-white crystalline powder. It is a nucleotide that is soluble in water and forms a clear solution.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate

The solubility of [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate (C10H14N5O7P) is an intriguing aspect due to its unique chemical structure. Several factors influence the solubility of this compound:

  • Polarity: The presence of multiple functional groups, including phosphate and hydroxyl groups, suggests that the compound might exhibit significant polarity, potentially enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The capability of forming hydrogen bonds due to -OH and -NH2 groups likely further increases its interaction with water, suggesting a reasonable solubility.
  • pH Influence: Being a phosphono compound, its solubility could be pH-dependent, where variations in pH may ionize or deprotonate the functional groups, affecting overall solubility.
  • Temperature: As with many chemical compounds, solubility may also vary with temperature, typically increasing with higher temperatures.

In summary, while qualitative insights indicate a favorable solubility in polar solvents, *quantitative data* regarding its solubility is essential for practical applications. Research studies and empirical testing will provide a clearer understanding of how environmental factors affect the solubility of this compound.

Interesting facts

Interesting Facts About [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl Phosphono Hydrogen Phosphate

This fascinating compound, recognized for its complex structure, is an intriguing subject of study in the fields of biochemistry and medicinal chemistry. Below are some key points that highlight its significance:

  • Unique Structure: The compound contains a purine derivative featuring a hydroxylated tetrahydrofuran ring, which contributes to its diverse biological activities.
  • Biological Relevance: Given the presence of the purine moiety, this compound may exhibit crucial roles in various biological processes, including nucleic acid biosynthesis.
  • Potential Therapeutics: The phosphono hydrogen phosphate functional group suggests potential applications in antiviral and anticancer therapies, as research indicates that modifications to purine structures can enhance their bioactivity.
  • Intriguing Mechanism of Action: The enzymatic pathways involving purine derivatives often offer insights into cellular signaling and metabolism, making this compound a significant focus of biochemical research.
  • Research Opportunities: Ongoing studies are exploring the interactions of this compound with enzymes and receptors, which might lead to the development of novel therapeutic agents.

In the words of famous chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." With compounds like this, scientists continually expand their horizons, leading to innovative discoveries in drug development.

Overall, [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate embodies the intricate relationship between structure and function, presenting challenges and opportunities that drive research forward.

Synonyms
[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonic acid
9-{2-deoxy-5-o-[hydroxy(phosphonooxy)phosphoryl]pentofuranosyl}-9h-purin-6-amine
DTXSID90863025
((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate
[5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
PD165868
NS00014811
Q2739886