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Adenosine monophosphate (AMP)

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

AMP is generally found as a solid at room temperature. It is stable and non-volatile under normal conditions. In its pure form, adenosine monophosphate is a crystalline material.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
334.00
Boiling point (Kelvin)
607.15
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.3000g/cm3
Appearence

Adenosine monophosphate typically appears as a white crystalline powder. It is odorless and has a slightly sweet taste. In solution, it may appear as a colorless to slightly yellow liquid depending on concentration and purity.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The solubility of the compound [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (C10H14N5O7P) is influenced by various factors due to its complex structure. Several aspects contribute to the assessment of its solubility:

  • Polarity: The presence of multiple functional groups, including hydroxyl and phosphate moieties, suggests that the compound is likely polar, which enhances its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the hydroxyl and amine groups to participate in hydrogen bonding typically increases the solubility of organic compounds in aqueous environments.
  • pH Dependence: As a dihydrogen phosphate, the compound's solubility may also vary with pH levels, particularly since phosphate groups can exist in different protonation states depending on the acidity of the solution.

In summary, the solubility of [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate is expected to be favorable in polar solvents, especially in biological or physiological conditions. This solubility profile could be crucial for its potential applications in biochemical pathways or pharmaceuticals.

Interesting facts

Overview of [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

[5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate is a fascinating compound with significant implications in biochemical research and drug development. As a derivative of purine, it showcases unique structural characteristics that contribute to its biological activity.

Key Features

  • Biological Relevance: This compound is closely related to nucleotides, which are the building blocks of nucleic acids like DNA and RNA, highlighting its potential roles in genetic processes.
  • Phosphate Group: The presence of a dihydrogen phosphate group is notable for its potential to participate in various biochemical pathways, including energy transfer and enzyme regulation.
  • Applications in Medicine: Its purine structure may enable it to interact with similar biological targets as nucleotides, suggesting possible applications in the design of antiviral or anticancer agents.

Interesting Insights

Compounds like this one are not just chemical entities but rather players in the complex game of molecular biology. As noted by scientists, "The understanding of purine derivatives is crucial for advancing therapeutic interventions." This emphasizes the importance of studying compounds that resemble naturally occurring biomolecules.

Research into this compound could lead to breakthroughs in:

  1. Targeted drug delivery systems
  2. Novel therapeutic agents for infectious diseases
  3. Innovative cancer treatments through nucleic acid interactions

In summary, [5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate serves as a prime example of how the intricate design of chemical compounds can influence biological systems and prompt scientific inquiry. Each exploration into its properties could unfold new layers of understanding in both chemistry and medicine.

Synonyms
Adenosine, 5'-phosphoric acid
Adenosine, 5'-(dihydrogen phosphate)
2'-Deoxy-5'-AMP
4-Dimethylaminobut-2-ynoic Acid Hydrochloride
NSC-77680
NSC-82625
SCHEMBL11927745
HMS3370G15
NSC77680
NSC82625
PdA
2'-deoxy-adenosine--5'-monophosphate
PHOSPHORIC ACID MONO-(5-(6-AMINO-PURIN-9-YL)-3-HO-4H-FURAN-2-YLMETHYL) ESTER