Skip to main content

Tenofovir

ADVERTISEMENT
Identification
Molecular formula
C9H14N5O4P
CAS number
147127-20-6
IUPAC name
[5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-yl] dihydrogen phosphate
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
287.22g/mol
Molar mass
287.2210g/mol
Density
1.4900g/cm3
Appearence

The compound typically appears as a white to off-white powder. It is crystalline in nature.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-yl] dihydrogen phosphate

The solubility of the compound [5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-yl] dihydrogen phosphate, with the chemical formula C9H14N5O4P, can be influenced by various factors.

  • Polarity: The presence of the phosphate group in the structure typically enhances the hydrophilicity of the molecule, making it more soluble in polar solvents, particularly water.
  • Functional Groups: The amine and furan components may also participate in hydrogen bonding, further increasing solubility in aqueous solutions.
  • Temperature: As with many compounds, solubility may increase with temperature, allowing for greater dissolution rates in heated solvents.
  • pH Levels: The degree of protonation of the amine group may also alter solubility, as a higher pH could lead to increased solubility due to the formation of positively charged species.

Overall, it's reasonable to anticipate that this compound is soluble in polar solvents such as water, given the presence of highly polar functional groups. However, specific solubility data would be essential for more precise predictions and practical applications.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-yl] dihydrogen phosphate

This compound, often referred to as an important component in the realm of biochemistry and molecular biology, holds a significant place due to its structural relationship with nucleotides and its role in cellular processes. Below are some intriguing highlights:

  • Structural Significance: The presence of the aminopurine moiety links this compound to the world of nucleic acids, particularly DNA and RNA, making it a focal point for studying genetic materials.
  • Enzyme Interaction: Compounds like this are vital in understanding enzyme-substrate interactions, which can pave the way for advancements in drug design and biotechnology.
  • Role in Phosphorylation: As a dihydrogen phosphate, this compound can participate in phosphorylation reactions, a fundamental mechanism for regulating protein function and activity within cells.
  • Potential Therapeutic Uses: The structure of this compound hints at possible applications in targeted therapies or as a tool in gene editing, showcasing its importance beyond basic research.

As stated by renowned biochemist, "Understanding these complex molecules is essential for unlocking the mysteries of life itself." The exploration of such compounds enriches our knowledge and fascination with the biochemical processes that sustain living organisms.

In summary, [5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-yl] dihydrogen phosphate is not just a simple chemical entity; it represents a convergence of chemical structure, biological significance, and therapeutic potential, encapsulating why chemistry is often referred to as the central science.

Synonyms
PHOSPHORIC ACID [5-(6-AMINOPURIN-9-YL)-2-METHYLTETRAHYDROFURAN-3-YL] ESTER
2' 5'-DIDEOXYADENOSINE 3'-MONOPHOSPHATE
121878-11-3
PD038824
5-(6-amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-yl dihydrogen phosphate