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Abacavir

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Identification
Molecular formula
C14H18N6O
CAS number
136470-78-5
IUPAC name
5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol
State
State

At room temperature, Abacavir is in a solid state, typically appearing as a powder.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
286.33g/mol
Molar mass
286.3320g/mol
Density
1.5100g/cm3
Appearence

Abacavir appears as a white to off-white crystalline powder. It is often found in its pure form or as part of pharmaceutical formulations, typically in tablets or oral solutions.

Comment on solubility

Solubility of 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol (C14H18N6O)

The solubility of 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol in various solvents is an interesting aspect to investigate due to its unique structural characteristics.

Factors Influencing Solubility

There are several factors that can affect the solubility of this compound:

  • Polarity: The presence of amino groups and hydroxyl groups can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can lead to increased solubility, especially in solvents that can engage in such interactions.
  • Temperature: Increasing temperature generally increases solubility, particularly for solid compounds.

Expected Solubility Characteristics

Based on its chemical structure, one might anticipate the following:

  • Potentially high solubility in water and ethanol, owing to its polar functional groups.
  • Low solubility in non-polar solvents such as hexane, due to the lack of non-polar characteristics in the molecule.
  • Variable solubility trends in mixed solvent systems can often be noted when tested experimentally.

In conclusion, while the theoretical aspects of solubility provide valuable insights, detailed experimental studies are crucial to determine the precise solubility profile of 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol across various solvents.

Interesting facts

Interesting Facts about 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol

This fascinating compound, known as 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol, is a notable member of the purine analogs family, which plays a significant role in biochemistry and medicine. Below are some intriguing insights surrounding this compound:

  • Structural Complexity: The molecule features a tetrahydrofuran ring, which contributes to its unique structure and properties. This type of ring is often found in various natural products and pharmaceuticals, providing both stability and flexibility.
  • Amino Group Importance: The presence of the amino group attached to the purine structure enhances the compound's ability to participate in biological reactions. Amino groups are essential in the creation of amines and can significantly modulate the biological activity of a compound.
  • Biological Relevance: Purines are essential components of nucleotides, which form DNA and RNA, making this compound potentially significant in genetic and therapeutic research.
  • Discovery Potential: Given the structural features of this compound, it may serve as a potential lead in drug discovery, especially in the fields of cancer research and antiviral agents.
  • Research Applications: Due to its unique combination of functional groups, the compound is a candidate for further study in medicinal chemistry, allowing scientists to explore its interactions with biomolecules.

In summary, 5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol stands at the intersection of structural chemistry and biological applications. Its unique functionalization not only showcases the diversity of organic compounds but also underscores the relevance of synthetic analogs in the field of drug development.

Synonyms
5-(6-aminopurin-9-yl)-2-methyl-3-oxolanol
5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol
13116-42-2
9-(2,5-dideoxypentofuranosyl)-9h-purin-6-amine
NSC95107
CHEMBL282503
SCHEMBL23396436
CHEBI:93820
DTXSID90927095
NSC95943
BDBM50140057
NSC-95107
AKOS032947862
PD069187
DB-054978
BRD-A20131130-001-01-7
Q27165549
5-(6-Amino-purin-9-yl)-2-methyl-tetrahydro-furan-3-ol
2-Hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetrahydro-furan-3,4-diol5-(6-Amino-purin-9-yl)-2-methyl-tetrahydro-furan-3-ol