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Tenofovir disoproxil fumarate

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Identification
Molecular formula
C19H30N5O10P
CAS number
147127-20-6
IUPAC name
[5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate
State
State

It is a solid at room temperature.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
560.00
Boiling point (Kelvin)
833.15
General information
Molecular weight
635.52g/mol
Molar mass
635.5150g/mol
Density
1.5000g/cm3
Appearence

Tenofovir disoproxil fumarate is a white to off-white crystalline powder. It is often provided in a stabilized form in pharmaceutical applications.

Comment on solubility

Solubility of [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate

This unique compound, with the formula C19H30N5O10P, presents intriguing characteristics regarding its solubility. Understanding solubility is crucial for applications in biochemistry and pharmaceuticals, as it influences the compound's behavior in biological systems.

Factors Influencing Solubility

The solubility of this compound can be affected by various factors, including:

  • Polarity: The presence of multiple functional groups, such as phosphate and hydroxyl groups, typically enhances polarity, which can facilitate solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds with solvent molecules can significantly enhance solubility.
  • Temperature: Generally, an increase in temperature can enhance solubility for many compounds.

Expected Solubility Behavior

Given its structural features, we can expect the following:

  • This compound is likely to be more soluble in aqueous environments due to its polar interactions.
  • It might demonstrate limited solubility in organic solvents, which aligns with the characteristics of many phosphoric acid derivatives.
  • If implemented in formulations or biological systems, its solubility may also be influenced by the presence of other compounds, ions, or proteins.

In summary, the solubility of [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate is primarily governed by its polar nature and the ability to engage in strong interactions with water. Understanding its solubility is key for harnessing its potential within various fields.

Interesting facts

Interesting Facts about [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate

This compound, with a fascinatingly complex structure, showcases the intricate beauty of biochemical systems. As a scientific system, it combines both organic and inorganic chemistry elements, displaying characteristics that are of particular interest to researchers in the fields of biochemistry and medicinal chemistry.

Key Highlights:

  • Biological Relevance: It is related to nucleotides and nucleosides, which play essential roles in cellular processes, including energy transfer and signal transduction.
  • Phosphorylation Potential: The presence of the phosphono group suggests high potential for interaction with biological systems, influencing various biochemical pathways.
  • Amino Group Insight: The amino group present on the purine base highlights the compound’s potential in drug development, particularly in targeting enzymes and receptors.
  • Versatile Applications: Compounds with similar structures are often studied for their antiviral and anticancer properties, making this compound a candidate for future therapeutic investigations.
  • Symmetry and Chirality: The tetrahydrofuran ring introduces chirality, which is significant in understanding how small changes in molecular structure can drastically alter biological activity.

"The potential of exploring complex molecular interactions cannot be overstated!"

The synthesis and characterization of such compounds can lead to enhanced understanding of molecular interactions, creating pathways toward novel therapeutic strategies. Continued research into compounds like this one is critical as we seek to elucidate the mysteries of life at the molecular level.

Synonyms
L000062