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Adefovir Dipivoxil

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Identification
Molecular formula
C20H32N5O8P
CAS number
147127-20-6
IUPAC name
[[5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] phosphate
State
State

At room temperature, Adefovir Dipivoxil is a solid. Due to its stability and form, it is usually handled as a powder, stored in airtight containers to protect it from moisture and contamination.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
731.00
Boiling point (Kelvin)
1 004.15
General information
Molecular weight
501.49g/mol
Molar mass
501.4920g/mol
Density
4.1203g/cm3
Appearence

Adefovir Dipivoxil appears as a white to off-white powder. It may have some crystalline characteristics depending on its purity and preparation method. When compounded into pharmaceutical products, it typically maintains a powder form or gets formulated into tablets.

Comment on solubility

Solubility of  [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] phosphate

The compound  [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl phosphate (C20H32N5O8P)

exhibits a complex solubility profile influenced by its unique chemical structure. When considering its solubility characteristics, several factors can be highlighted:

  • Polarity: The presence of multiple hydroxyl groups and the phosphate moiety contributes to the overall polarity of the molecule, suggesting potential solubility in polar solvents such as water.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds may enhance its solubility in aqueous environments, allowing it to interact favorably with water molecules.
  • Structural Complexity: The intricate arrangement and substitution patterns within the compound can create steric hindrance, potentially impacting its solubility in less polar solvents.
  • Concentration Dependence: Like many compounds, solubility can vary with concentration; higher concentrations may lead to reduced solubility due to saturation limits.

Overall, while the compound's polar characteristics suggest a tendency for solubility, experimental data would be essential to confirm the precise behavior in different solvent systems. As with many complex organic phosphates, understanding its solubility is crucial for its application in biochemical contexts.

Interesting facts

Exploring the Compound: [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl phosphate

This fascinating compound belongs to a class of chemicals known for their roles in various biological processes, particularly in the realm of **nucleic acids** and **energy transfer**. It contains a purine base, contributing to its potential interaction with nucleotides, which are the building blocks of DNA and RNA. Here are some interesting facts about this compound:

  • Biological Relevance: Compounds similar to this one are often involved in signal transduction pathways and energy metabolism, highlighting their importance in cellular functions.
  • Phosphorylation: The presence of a phosphoryl group suggests that this compound may undergo phosphorylation reactions, which can significantly alter its activity and interactions in biological systems.
  • Potential Therapeutics: Given its structure, it may have implications in treating diseases where nucleotide synthesis or metabolism is disrupted, such as cancers or metabolic disorders.
  • Synthetic Utility: This complex structure reflects the *advancements in synthetic organic chemistry*, as chemists can create compounds with precise modifications to potentially enhance their biological functions.

The intricate design of [5-(6-amino-2-methylsulfanyl-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl phosphate not only serves as a testament to the marvels of chemical synthesis but also paves the way for future discoveries in the field of medicinal chemistry.

As a chemistry student or scientist, understanding such compounds deepens your insight into the interplay between structure and function, inviting a deeper appreciation for the complexity of biological molecules and their potential in innovative therapeutic strategies.