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Tenofovir

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Identification
Molecular formula
C9H14N5O4P
CAS number
147127-20-6
IUPAC name
5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide
State
State

At room temperature, Tenofovir is a solid substance presented as a crystalline powder.

Melting point (Celsius)
276.00
Melting point (Kelvin)
549.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
287.21g/mol
Molar mass
287.2130g/mol
Density
1.4900g/cm3
Appearence

Tenofovir is typically a white to off-white crystalline powder. It is known for being soluble in water and slightly soluble in acetonitrile.

Comment on solubility

Solubility Characteristics of 5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide

The solubility of the compound with the chemical formula C9H14N5O4P is an interesting aspect to explore, particularly due to its complex structure and functional groups. Understanding solubility can provide insight into its biological activity and potential applications. Here are a few key points to consider:

  • Solvent Interaction: The presence of multiple functional groups, such as amines and hydroxyl groups, suggests that this compound may exhibit enhanced solubility in polar solvents, particularly in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds is often a critical factor in solubility. The compound’s hydroxyl and amine functionality may promote strong interactions with water molecules.
  • pH Dependency: The solubility could be influenced by the pH of the solution, where certain functional groups may become ionized, altering their solubility characteristics.
  • Temperature Effects: As with many compounds, increasing temperature often increases solubility due to greater molecular motion, facilitating interactions with solvent molecules.

In conclusion, while exact solubility data may vary based on specific conditions, the intricate nature of 5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide likely contributes to its favorable solubility profile in suitable solvents, making it a compound of interest for further examination in various applications.

Interesting facts

Interesting Facts about 5-[6-[(4-Aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide

This intriguing compound belongs to the class of purine derivatives, which play a critical role in various biological processes. Here are some fascinating insights about this compound:

  • Biological Importance: Purines are essential building blocks for DNA and RNA, making this compound particularly relevant in genetic studies and biochemistry.
  • Pharmacological Potential: Given its structural complexity, this compound may exhibit significant pharmacological properties, particularly in drug design and discovery.
  • Mechanism of Action: The presence of the 4-aminophenyl group suggests potential interactions with various biological targets, enhancing its applicability in medicinal chemistry.
  • Structure-Activity Relationship: The intricate modifications in the molecular structure can be pivotal for studying structure-activity relationships, crucial for developing effective therapeutic agents.
  • Research Applications: This compound could serve as a valuable lead in research aimed at targeting specific enzymes or receptors, contributing to advancements in treating diseases.

As noted by well-respected chemists, “The future of medicine is in biomolecular engineering, and compounds like these are at the forefront of that revolution.” The exploration of such compounds will continue to pave the way for innovative treatments and deepen our understanding of complex biological systems.

In summary, this compound exemplifies the intersection of organic chemistry and medicinal applications, showcasing how intricate molecular designs can lead to significant scientific breakthroughs.

Synonyms
AB-MECA
5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
BCP16462
L000703