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Adenosylcobalamin

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Identification
Molecular formula
C72H100CoN18O17P
CAS number
13870-90-1
IUPAC name
[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate
State
State

At room temperature, adenosylcobalamin exists as a solid. It is typically stored in a dark, airtight container to avoid degradation by light and moisture.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1579.58g/mol
Molar mass
1 579.8000g/mol
Density
1.4400g/cm3
Appearence

Adenosylcobalamin, also known as coenzyme B12, generally appears as a crystalline, dark red compound. It is often found in the form of needles and is sensitive to light leading to photolysis.

Comment on solubility

Solubility of the Compound

The solubility of the compound [5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate with the formula C72H100CoN18O17P can be quite complex. Its solubility is influenced by several factors, including:

  • Hydrophobic sections: The presence of numerous hydrocarbon chains can lead to low solubility in polar solvents, making it potentially better soluble in organic solvents.
  • Functional groups: Hydroxyl and amino groups may enhance solubility in water, providing sites for hydrogen bonding.
  • Ionic character: The phosphate group contributes to the overall ionic character, which can offer better solubility in aqueous media.

In summary, the solubility of this compound is expected to demonstrate:

  • A greater solubility in organic solvents
  • Moderate to good solubility in water due to polar functional groups
  • Variability based on pH and temperature conditions

Due to the interaction between various functional groups and the overall molecular structure, it is essential to conduct solubility tests in different solvents to obtain precise data. As a general reminder, "a compound’s solubility is a dynamic property that can change with its environment." Understanding these characteristics can greatly enhance its applications in different chemical processes.

Interesting facts

Interesting Facts about [5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate

This compound is a complex organic molecule, entailing a rich structural diversity and unique functionalities. Its intricate framework makes it a significant subject of study in organic and medicinal chemistry. Below are some fascinating insights about this compound:

  • Biological Relevance: The presence of the tetrahydrocorrin structure indicates potential biological roles, especially in medicinal chemistry and catalysis.
  • Pharmacological Potential: Due to its elaborate design, this compound could serve as a candidate for therapeutics targeting specific diseases, particularly those involving coenzyme B12 analogs.
  • Chemical Complexity: The assembly of multiple functional groups, such as hydroxymethyl and amino substituents, contributes to the compound’s reactivity and interaction with biological systems.
  • Research Insights: Scientists are intrigued by how the unique combination of substituted benzimidazole and tetrahydrofuran components may enhance the stability and efficacy of drugs derived from this structure.

In the words of a renowned chemist, "Nature is adept at creating complex molecules where each atom plays its part in a broader symphony of interaction."

This compound not only exemplifies the artistry of chemical synthesis but also paves the way for potential innovations in drug design and environmental chemistry. Continuing to explore its properties and reactions will likely yield exciting discoveries in the field!