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5-(4-nitrophenyl)sulfonylthiazol-2-amine

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Identification
Molecular formula
C9H7N3O4S2
CAS number
120-71-8
IUPAC name
5-(4-nitrophenyl)sulfonylthiazol-2-amine
State
State

At room temperature, 5-(4-nitrophenyl)sulfonylthiazol-2-amine is typically found as a solid. It is stable under standard conditions, making it suitable for various chemical reactions and applications where solid-phase materials are required.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
294.29g/mol
Molar mass
294.2890g/mol
Density
1.5500g/cm3
Appearence

The compound 5-(4-nitrophenyl)sulfonylthiazol-2-amine typically appears as a crystalline solid. The crystals may be colored due to the presence of the nitrophenyl group, which is known to impart a yellowish hue. The structure itself combines the thiazole and the nitrophenyl moiety, making it likely to exhibit an aromatic character.

Comment on solubility

Solubility of 5-(4-nitrophenyl)sulfonylthiazol-2-amine (C9H7N3O4S2)

The solubility of 5-(4-nitrophenyl)sulfonylthiazol-2-amine is an important aspect to consider for its applications and behavior in various environments. This compound tends to exhibit varying solubility based on several factors:

  • Polarity: Due to the presence of sulfonyl (–SO2–) and nitro (–NO2) groups, the compound may have increased polarity. This often enhances solubility in polar solvents such as water.
  • Functional Groups: The thiazole ring and amine group contribute to the overall solubility characteristics. The amine, being a basic functional group, can engage in hydrogen bonding, making the compound more soluble in polar solvents.
  • Solvent Effects: The solubility can differ significantly in organic solvents versus aqueous solutions. For example, it may show higher solubility in dimethyl sulfoxide (DMSO) and other polar aprotic solvents.

However, it is essential to note that the exact solubility can vary based on temperature, concentration, and the presence of other solutes in a given solution. Overall, while there are factors that suggest reasonable solubility, experimental data is crucial for precise values.

In summary, for practical applications, understanding and testing the solubility of 5-(4-nitrophenyl)sulfonylthiazol-2-amine in relevant solvents is key to harnessing its full potential in chemical processes.

Interesting facts

Interesting Facts about 5-(4-nitrophenyl)sulfonylthiazol-2-amine

The compound 5-(4-nitrophenyl)sulfonylthiazol-2-amine is a fascinating molecule with a variety of intriguing properties and applications. Here are some key points to consider:

  • Structure and Features: This compound contains a thiazole ring fused with an amine group, coupled with a sulfonyl moiety and a nitrophenyl group. The presence of these functional groups significantly affects its reactivity and chemical behavior.
  • Biological Significance: Compounds like this one are frequently investigated for their potential as pharmaceutical agents. The thiazole ring, in particular, is common in medicinal chemistry, often associated with antibacterial and antifungal activity.
  • Mechanism of Action: The nitrophenyl group may enhance properties of the molecule by participating in electron-withdrawing mechanisms, which can influence substitution reactions and overall reactivity.
  • Research Applications: This compound can serve as a useful building block in organic synthesis. Its structure allows chemists to explore variations and create derivatives with potentially improved pharmacological characteristics.
  • Environmental Considerations: As with many organic compounds, studying the environmental impact of 5-(4-nitrophenyl)sulfonylthiazol-2-amine is crucial, especially regarding its degradation products and persistence in biological systems.

In summary, 5-(4-nitrophenyl)sulfonylthiazol-2-amine is not just a simple molecule but a complex structure that opens doors to numerous research avenues in chemistry and pharmaceuticals. As scientists continue to explore its properties, there is potential for discovering new applications and benefits within various fields.

Synonyms
39565-05-4
2-Amino-5-(4-nitrophenylsulfonyl)thiazole
5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-amine
5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-amine
2-Amino-5-(p-nitrobenzenesulfonyl)thiazole
2-Amino-5-(p-nitrophenylsulfonyl)thiazole
2-Thiazolamine, 5-[(4-nitrophenyl)sulfonyl]-
p-Nitrophenyl-2-aminothiazol-5-ylsulphone
THIAZOLE, 2-AMINO-5-(p-NITROPHENYLSULFONYL)-
2-Amino-5-(4-Nitrophenylsulfonyl)-Thiazole
Thiazole, 2-amino-5-((p-nitrophenyl)sulfonyl)-
5-(4-nitrobenzenesulfonyl)-1,3-thiazol-2-amine
MLS002694011
2-Thiazolamine, 5-((4-nitrophenyl)sulfonyl)-
WLN: T5N CSJ BZ DSWR DNW
NSC-77091
5-((4-Nitrophenyl)sulfonyl)thiazol-2-amine
C9H7N3O4S2
Thiazole, 2-amino-5-[(p-nitrophenyl)sulfonyl]-
EINECS 254-515-2
NSC 77091
BRN 0283324
AI3-52559
MFCD00005327
5-(4-nitrophenylsulfonyl)thiazol-2-amine
PRE5B7RF4R
Oprea1_552025
Oprea1_618397
4-27-00-05399 (Beilstein Handbook Reference)
5-(4-NITROPHENYLSULFONYL)THIAZOLE-2-AMINE
CHEMBL347345
SCHEMBL1062638
GKTKCGAOXFHFTD-UHFFFAOYSA-
DTXSID80192679
HMS3094E05
ALBB-021293
NSC77091
BBL005425
STK985634
AKOS000119912
5-(4-Nitrophenyl)sulfonylthiazol-2-amine
SMR001559945
VS-01578
2-Amino-5-(4-nitrobenzenesulfonyl)thiazole
DB-008155
2-Amino-5-[(p-nitrophenyl)sulfonyl]thiazole
5-[(4-Nitrophenyl)sulfonyl]-2-thiazolamine
NS00030600
2-amino-5-[(4-nitrophenyl)sulfonyl]thiazole
EN300-21240
2-Amino-5-(p-nitrophenylsulfonyl)-1,3-thiazole
5-(4-nitrophenylsulfonyl)-1,3-thiazol-2-amine
5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-ylamine #
F3096-1696
Z104494792
254-515-2
InChI=1/C9H7N3O4S2/c10-9-11-5-8(17-9)18(15,16)7-3-1-6(2-4-7)12(13)14/h1-5H,(H2,10,11)