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5-(4-Morpholinophenyl)sulfanylquinazoline-2,4-diamine

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Identification
Molecular formula
C17H19N5O1S1
CAS number
179688-29-0
IUPAC name
5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine
State
State

At room temperature, 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine exists in a solid state. It is stable under normal conditions but may require proper storage conditions to maintain its stability and efficacy.

Melting point (Celsius)
230.15
Melting point (Kelvin)
503.30
Boiling point (Celsius)
625.95
Boiling point (Kelvin)
899.10
General information
Molecular weight
370.46g/mol
Molar mass
370.4560g/mol
Density
1.4599g/cm3
Appearence

The substance typically appears as a crystalline powder. Its color can range from off-white to pale yellow.

Comment on solubility

Solubility of 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine

The solubility of the compound 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine (C17H19N5O1S1) is a topic of particular interest due to its unique structural features. Understanding its solubility can inform various applications and behavior in different environments.

Key points regarding the solubility of this compound include:

  • Polar and Non-Polar Components: The presence of both polar (amine and morpholine) and non-polar (phenyl and sulfanyl) groups influences solubility in different solvents.
  • Solvent Interaction: This compound is likely to be more soluble in polar protic solvents such as water or alcohol due to the ability of these solvents to form hydrogen bonds with the amino groups.
  • Solubilization Techniques: For practical uses, methods such as micellar solubilization or the use of co-solvents can enhance solubility, especially for pharmaceutical applications.
  • Temperature Effect: Solubility may vary significantly with temperature; generally, an increase in temperature leads to an increase in solubility for many compounds.
  • pH Dependence: The solubility can also be influenced by pH, particularly through protonation of amine groups which increases solubility in acidic conditions.

In summary, the solubility of 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine is multifactorial and can be optimized by considering the chemical environment and physical conditions during its application.

Interesting facts

Interesting Facts about 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine

5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine is a fascinating compound that has attracted the attention of chemists and researchers due to its diverse applications and unique structure. Here are some intriguing aspects:

  • Complex Structure: The compound features a quinazoline core, a bicyclic structure that is often found in biologically active molecules. The incorporation of a morpholinophenyl group adds to its complexity and potential reactivity.
  • Biological Significance: Compounds with quinazoline structures have shown a variety of biological activities, including antitumor, antiviral, and anti-inflammatory properties. Research continues to explore the potential pharmacological benefits of this specific compound.
  • Versatile Applications: Beyond its biological implications, such compounds can be utilized in pharmaceuticals, agrochemicals, and functional materials with applications ranging from drug development to agricultural enhancements.
  • Synthetic Pathways: The synthesis of this molecule involves multiple steps, combining various organic chemistry techniques that highlight the ingenuity of modern synthesis methods. Chemists often use strategies such as nucleophilic substitutions and coupling reactions to construct these sophisticated architectures.
  • Research Opportunities: Ongoing studies on derivatives and analogs of this compound may lead to the discovery of new therapeutic agents, demonstrating the importance of continued research in this area.

In summary, the structurally complex 5-(4-morpholinophenyl)sulfanylquinazoline-2,4-diamine represents an exciting topic of study in modern chemistry, promising contributions to medicine and materials science. As we deepen our understanding of such compounds, their potential continues to expand, revealing new pathways for innovation and discovery.

Synonyms
5-(4-MORPHOLIN-4-YL-PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE
5-{[4-(morpholin-4-yl)phenyl]sulfanyl}quinazoline-2,4-diamine
5-((4-(morpholin-4-yl)phenyl)sulfanyl)quinazoline-2,4-diamine
gw2021
TQ6
CHEMBL328827
SCHEMBL4316405
BDBM18048
DB02001
PD008231
NS00070461
Q27093092
5-[(4-morpholin-4-ylphenyl)sulfanyl]quinazoline-2,4-diamine
5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOLINEDIAMIN