Interesting facts
Interesting Facts about 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)methoxy]phenyl]methyl]thiazolidine-2,4-dione
This fascinating compound, known for its intricate structure and various biological properties, is a member of the thiazolidine family, which is recognized for its potential therapeutic applications. Here are some compelling aspects of this compound:
- Natural Origins: It features a chroman ring, a component commonly found in natural products, especially those derived from plants. This structural motif is associated with several antioxidant properties, making the compound interesting for research in natural product chemistry.
- Biological Activities: Compounds with thiazolidine scaffolds have been studied for their role in metabolic functions. There is ongoing research exploring their potential in anti-diabetic treatments and restorative functions in cellular metabolism.
- Complexity: The detailed structure exemplifies the complexity often encountered in organic chemistry. The ability to build such intricate molecules is a testament to the sophistication of synthetic methodologies available today.
- Research Potential: Ongoing investigations into this compound may manifest breakthroughs in understanding its mechanistic pathways, particularly in relation to oxidative stress and inflammation, which are critical factors in many chronic diseases.
- Pharmaceutical Implications: Given the bioactive properties exhibited by thiazolidine derivatives, this compound shows potential as a lead structure for new drug designs targeting metabolic and inflammatory pathways.
In summary, the multi-dimensional nature of 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)methoxy]phenyl]methyl]thiazolidine-2,4-dione not only highlights the beauty of molecular architecture but also opens doors for future exploration in medicinal chemistry.
Synonyms
troglitazone
97322-87-7
Rezulin
Romglizone
Prelay
CS-045
Romozin
Noscal
troglitazona
Rezulin (TN)
troglitazonum
CS 045
CI-991
GR 92132X
CCRIS 8969
GR92132X
CI 991
GR-92132X
CHEBI:9753
5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione
UNII-I66ZZ0ZN0E
(+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione
BRN 4338399
DTXSID8023719
5-(4-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
Troglitazone (CS-045)
I66ZZ0ZN0E
DTXCID603719
5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
NCGC00164445-01
5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
C24H27NO5S
BDBM50101974
5-[(4-{[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methyl]oxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
CAS-97322-87-7
SR-05000000454
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione
Troglitazone (JAN/USAN/INN)
Troglitazone [USAN:INN:BAN]
5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]thiazolidine-2,4-dione
CS045
2,4-thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-
5-(4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy)benzyl)-1,3-thiazolidine-2,4-dione
(+/-)-5-[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione
Troglitazone (Standard)
Spectrum5_001973
UPCMLD-DP017
SCHEMBL4959
TROGLITAZONE (MART.)
MLS006010817
GTPL2693
CHEMBL3542292
UPCMLD-DP017:001
UPCMLD-DP017:002
A10BG01
Troglitazone, >=98% (HPLC)
GLXC-03930
HMS2089D22
HMS2093D04
HMS3649G12
HMS3713D08
5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-2,4-Thiazolidinedione
BCP06753
EX-A3782
Tox21_112119
Tox21_300470
BDBM50088494
HB2559
HSCI1_000037
HY-50935R
s8432
AKOS000281116
AKOS024457434
Tox21_112119_1
Troglitazone - CAS 97322-87-7
CCG-208125
CS-1634
DB00197
FT28613
SMP2_000224
NCGC00161599-01
NCGC00161599-02
NCGC00161599-03
NCGC00161599-04
NCGC00161599-05
NCGC00161599-06
NCGC00161599-07
NCGC00161599-08
NCGC00161599-09
NCGC00161599-11
NCGC00254440-01
AC-31453
AS-56378
HY-50935
SMR001550129
DB-057670
NS00015646
T3920
D00395
H12073
AB00643330-02
Q7844989
SR-05000000454-2
SR-05000000454-3
SR-05000000454-5
BRD-A13084692-001-02-5
BRD-A13084692-001-17-3
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy)benzyl)-2,4-thiazolidinedione
5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]-2,4-dioxothiazolidine
5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]thiazolidine -2,4-dione
(5R)-5-[[4-[[(2S)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl]methoxy]phenyl]methyl]thiazolidine-2,4-dione
2,4-Thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]- (9CI)
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione)-T
5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)-1,3-thiazolidine-2,4-dione
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7 ,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl ]methyl]-2,4-thiazolidinedione
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1- benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazlidinedione
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione;CI 991;CS 045
5-[[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-{4-(6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-yl-methoxy) benzyl) thiazolidine-2,4-dione
Solubility of 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)methoxy]phenyl]methyl]thiazolidine-2,4-dione
The solubility of the compound C24H27NO5S, known as 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)methoxy]phenyl]methyl]thiazolidine-2,4-dione, can vary based on several factors. Understanding its solubility characteristics is essential for applications in pharmaceuticals and other fields. Here are key points to consider:
Due to its complex structure, it is suggested to conduct empirical solubility tests for precise data. As the renowned chemist Richard Feynman once remarked, "The only way to truly understand a phenomenon is to test it." Thus, exploration of this compound's solubility is imperative for both theoretical studies and practical applications.