Interesting facts
Interesting Facts about 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
The compound 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine is a fascinating member of the pyrimidine family, known for its diverse applications in pharmaceuticals and organic chemistry. Here are some noteworthy insights:
- Structural Complexity: The presence of both a pyrimidine ring and a trimethoxyphenyl group in its structure makes this compound particularly interesting for chemists. The multiple functional groups contribute to its unique chemical reactivity.
- Pharmacological Potential: Compounds with pyrimidine rings are often explored for their medicinal properties. This specific compound could potentially serve as a lead structure for developing new drugs, particularly in treating various diseases due to its nitrogen-rich heterocyclic nature.
- Synthetic Pathways: The synthesis of this compound may involve intricate multi-step reactions, showcasing the beauty and complexity of synthetic organic chemistry. Understanding the synthetic routes can provide insights into method optimization and the development of new reactions.
- Intermolecular Interactions: The trimethoxyphenyl group may facilitate strong intermolecular interactions, influencing the compound's properties and behavior in biological systems. This highlights the importance of functional group modifications in tailoring molecular interactions.
- Potential Applications: In addition to its medicinal properties, this compound could find uses in materials science, such as organic light-emitting diodes (OLEDs) or as components in sensors due to its electronic properties.
As a chemistry student, exploring compounds like 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine not only enhances your understanding of structural chemistry but also inspires creativity in designing novel compounds for future research. "In chemistry, the beauty of the compound lies in its potential." Remember, the world of chemical compounds is vast and continuously evolving!
Synonyms
trimethoprim
738-70-5
Proloprim
Trimpex
Trimetoprim
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Monotrim
Monotrimin
Trimopan
Wellcoprim
Bactramin
Monoprim
Syraprim
Triprim
Uretrim
Trimethoprime
Trimethoprimum
5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
Trimetoprima
Abaprim
Briscotrim
Novotrimel
Streptoplus
Sulfoxaprim
Trimethioprim
Urobactrim
Wellcoprin
Anitrim
Antrima
Antrimox
Bacidal
Bacticel
Bactoprim
Bencole
Bethaprim
Biosulten
Chemotrin
Colizole
Conprim
Cotrimel
Duocide
Esbesul
Espectrin
Euctrim
Exbesul
Fermagex
Fortrim
Ikaprim
Kombinax
Lagatrim
Lastrim
Metoprim
Pancidim
Protrin
Resprim
Salvatrim
Setprin
Sinotrim
Sugaprim
Sulfamar
Sulthrim
Sultrex
Trimexol
Trimezol
Trimono
Trisulcom
Trisulfam
Trisural
Utetrin
Velaten
Xeroprim
Zamboprim
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Bacdan
Bacide
Bacin
Bacta
Deprim
Futin
Omstat
Purbal
Roubac
Roubal
Stopan
Toprim
Trisul
Co-Trimoxizole
Lagatrim Forte
component of Bactrim
Septrin Forte
Trimpex 200
Alcorim-F
Colizole DS
Septrin S
Septrin DS
NSC-106568
Trimez-IFSA
U-Prin
component of Septra
Dosulfin
NIH 204
Resprim Forte
BW 56-72
Uro-D S
Tmp Smx
Infectotrimet
Trimethoprime [INN-French]
Trimethoprimum [INN-Latin]
Trimetoprima [INN-Spanish]
2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-
Bacterial [Antibiotic]
CCRIS 2410
NSC 106568
WR 5949
CHEBI:45924
HSDB 6781
TCMDC-125538
BW-56-72
5-(3,4,5-Trimethoxybenzyl)-2,4-diaminopyrimidine
EINECS 212-006-2
UNII-AN164J8Y0X
MFCD00036761
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
BRN 0625127
AN164J8Y0X
2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)methyl)-
DTXSID3023712
AI3-52594
NIH-204
Pyrimidine, 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-
CHEMBL22
Trimpex (TN)
NSC106568
Apo-Sulfatrim
BW 5672
Trimethoprim-d3 (Major)
MLS000079023
DTXCID803712
5-((3,4,5-Trimethoxyphenyl)methyl)-2,4-pyrimidinediamine
2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)-methyl)-
5-25-13-00429 (Beilstein Handbook Reference)
COTRIM COMPONENT TRIMETHOPRIM
SEPTRA COMPONENT TRIMETHOPRIM
BACTRIM COMPONENT TRIMETHOPRIM
Co-trimoxazole component trimethoprim
UROPLUS COMPONENT TRIMETHOPRIM
SULFATRIM COMPONENT TRIMETHOPRIM
SULMEPRIM COMPONENT TRIMETHOPRIM
BW-5672
BACTRIM DS COMPONENT TRIMETHOPRIM
Bacterial (Antibiotic)
NCGC00016055-05
Trimethoprim [USAN:USP:INN:BAN:JAN]
Trimethopriom
Bactifor
CAS-738-70-5
Instalac
SMR000035999
Trimetoprim [DCIT]
Trimogal
COTRIM D.S. COMPONENT TRIMETHOPRIM
Lescot
Tiempe
Trimetoprim [Polish]
SULFAMETHOPRIM COMPONENT TRIMETHOPRIM
Trimethoprim 100 microg/mL in Acetonitrile
BACTRIM PEDIATRIC COMPONENT TRIMETHOPRIM
Trimethoprime (INN-French)
Trimethoprimum (INN-Latin)
Trimetoprima (INN-Spanish)
TRIMETHOPRIM (MART.)
TRIMETHOPRIM [MART.]
TRIMETHOPRIM (USP-RS)
TRIMETHOPRIM [USP-RS]
2,4-Diamino-5-(3',4',5'-trimethoxybenzyl)pyrimidine
TRIMETHOPRIM (EP IMPURITY)
TRIMETHOPRIM [EP IMPURITY]
TRIMETHOPRIM (EP MONOGRAPH)
TRIMETHOPRIM [EP MONOGRAPH]
NIH 204 (VAN)
TRIMETHOPRIM (USP MONOGRAPH)
TRIMETHOPRIM [USP MONOGRAPH]
Proloprim (TN)
Trimethoprim (USAN:USP:INN:BAN:JAN)
Trimethoprim D3 (4-methoxy D3)
SR-01000075652
5-(3, 4, 5-Trimethoxybenzyl)-2, 4-pyrimidinediamine
Trimethoprim & VRC3375
5-(3,4,5-Trimethoxybenzyl)-2,4-pyrimidinediamine
Trimethoprim (JAN/USP/INN)
5-{[3,4,5-tris(methyloxy)phenyl]methyl}pyrimidine-2,4-diamine
B-Lock
KUC103659N
Trimethoprim,(S)
Prestwick_485
KSC-4-158
Trimethoprim (TMP)
Bactrim (Salt/Mix)
Spectrum_000167
Tocris-0650
2w9h
3fl9
3n0h
3s3v
4km2
Trimethoprim (Standard)
Trimethoprim D3 (4-methoxy D3) 100 microg/mL in Acetonitrile
Opera_ID_1760
Prestwick0_000208
Prestwick1_000208
Prestwick2_000208
Prestwick3_000208
Spectrum2_000937
Spectrum3_000643
Spectrum4_000372
Spectrum5_001559
Lopac-T-7883
TRIMETHOPRIM [MI]
TRIMETHOPRIM [INN]
TRIMETHOPRIM [JAN]
Epitope ID:119684
UPCMLD-DP132
T 7883
TRIMETHOPRIM [HSDB]
TRIMETHOPRIM [USAN]
TRIMETHOPRIM [VANDF]
Lopac0_001271
Oprea1_495058
SCHEMBL24506
BSPBio_000195
BSPBio_002245
KBioGR_000863
KBioSS_000647
MLS001201740
MLS002303068
MLS002548881
BIDD:GT0190
DivK1c_000589
SPECTRUM1500595
TRIMETHOPRIM [WHO-DD]
SPBio_000874
SPBio_002116
BPBio1_000215
UPCMLD-DP132:001
BDBM18069
GTPL10931
HMS501N11
HY-B0510R
KBio1_000589
KBio2_000647
KBio2_003215
KBio2_005783
KBio3_001465
J01EA01
MSK4009
TRIMETHOPRIM [GREEN BOOK]
Trimethoprim, >=98% (HPLC)
NINDS_000589
2,4,5-trimethoxybenzyl)pyrimidine
HMS1568J17
HMS1921I03
HMS2090D14
HMS2092A10
HMS2095J17
HMS2230L06
HMS3259I11
HMS3263P04
HMS3371O18
HMS3652E03
HMS3712J17
Pharmakon1600-01500595
TRIMETHOPRIM [ORANGE BOOK]
Trimethoprim for system suitability
2,4,5-trimethoxyphenzyl)pyrimidine
ALBB-028968
BCP12148
HY-B0510
PXB92338
Tox21_110291
Tox21_200157
Tox21_501271
BBL005584
CCG-40335
NSC752719
NSC757370
s3129
STK177322
STL455117
TRIMETHOPRIMUM [WHO-IP LATIN]
AKOS001650069
Tox21_110291_1
AC-8427
DB00440
KS-1145
LP01271
NC00483
NSC-752719
NSC-757370
SDCCGSBI-0051237.P004
TRIMETHOPRIM COMPONENT OF COTRIM
TRIMETHOPRIM COMPONENT OF SEPTRA
IDI1_000589
SMP2_000262
TRIMETHOPRIM COMPONENT OF BACTRIM
TRIMETHOPRIM COMPONENT OF UROPLUS
NCGC00016055-01
NCGC00016055-02
NCGC00016055-03
NCGC00016055-04
NCGC00016055-06
NCGC00016055-07
NCGC00016055-08
NCGC00016055-09
NCGC00016055-10
NCGC00016055-11
NCGC00016055-12
NCGC00016055-13
NCGC00016055-14
NCGC00016055-16
NCGC00016055-17
NCGC00016055-27
NCGC00024707-01
NCGC00024707-03
NCGC00024707-04
NCGC00024707-05
NCGC00024707-06
NCGC00024707-07
NCGC00024707-08
NCGC00257711-01
NCGC00261956-01
SY031734
TRIMETHOPRIM COMPONENT OF SULFATRIM
TRIMETHOPRIM COMPONENT OF SULMEPRIM
Trimethoprim/sulfamethoxazole (commercial)
SBI-0051237.P003
DB-055812
TRIMETHOPRIM COMPONENT OF BACTRIM DS
2, 5-[(3,4,5-trimethoxyphenyl)methyl]-
AB00052118
EU-0101271
NS00000211
SW196690-3
T2286
Trimethoprim 1000 microg/mL in Acetonitrile
TRIMETHOPRIM COMPONENT OF COTRIM D.S.
C01965
D00145
EN300-118703
TRIMETHOPRIM COMPONENT OF SULFAMETHOPRIM
Trimethoprim, crystallized, >=99.0% (HPLC)
WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1
5-(3,5-Trimethoxybenzyl)-2,4-diaminopyrimidine
AB00052118-30
AB00052118-32
AB00052118_33
AB00052118_34
Trimethoprim, VETRANAL(TM), analytical standard
Q422665
TRIMETHOPRIM COMPONENT OF BACTRIM PEDIATRIC
2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine
Pyrimidine,4-diamino-5-(3,4,5-trimethoxybenzyl)-
SR-01000075652-1
SR-01000075652-3
SR-01000075652-6
5-(3,4,5-Trimethoxybenzyl)-2,4-pyrimidinediamine #
BRD-K07208025-001-06-5
BRD-K07208025-001-29-7
BRD-K07208025-001-31-3
SR-01000075652-10
F0914-5266
Trimethoprim, certified reference material, TraceCERT(R)
Z1515385071
5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4(1H,3H)-diimine
5-(3,4,5-Trimethoxyphenyl)methyl)-2,4-pyrimidinediamine
5-(3,4,5-TRIMETHYOXYBENZYL)-2,4-DIAMINOPYRIMIDINE
pyrimidine, 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-
Trimethoprim, British Pharmacopoeia (BP) Reference Standard
Trimethoprim, European Pharmacopoeia (EP) Reference Standard
5-((3,4,5-TRIMETHOXYPHENYL)-METHYL-2,4-PYRIMIDINEDIAMINE
Trimethoprim, United States Pharmacopeia (USP) Reference Standard
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine;Instalac;Proloprim
Trimethoprim for system suitability, European Pharmacopoeia (EP) Reference Standard
Trimethoprim, Pharmaceutical Secondary Standard; Certified Reference Material
212-006-2
Solubility of 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
The solubility of the compound 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine (C14H18N4O3) is influenced by several factors:
Because of these factors, one might find this compound to be sparingly soluble in water but potentially more soluble in organic solvents. As per the common solubility rule: "like dissolves like," the molecular structure suggests its behavior is aligned with organic solvent interaction.
Understanding the solubility of this compound is crucial for its applications in various chemical processes, formulations, and potential pharmaceutical relevance.