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5-(3-pyridylmethyl)benzofuran-2-carboxylic acid

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Identification
Molecular formula
C16H11NO3
IUPAC name
5-(3-pyridylmethyl)benzofuran-2-carboxylic acid
State
State

At room temperature, this compound is typically found in a solid state. It is usually handled as a dry powder.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
415.00
Boiling point (Kelvin)
688.15
General information
Molecular weight
265.27g/mol
Molar mass
265.2720g/mol
Density
1.3560g/cm3
Appearence

This compound typically appears as an off-white to pale yellow powder. It is generally crystalline in nature, depending on the method of synthesis and purification.

Comment on solubility

Solubility of 5-(3-pyridylmethyl)benzofuran-2-carboxylic acid

The solubility of 5-(3-pyridylmethyl)benzofuran-2-carboxylic acid, with the chemical formula C16H11NO3, presents interesting characteristics that are often influenced by its molecular structure.

Key Factors Affecting Solubility:

  • Functional Groups: The presence of the carboxylic acid group (-COOH) can significantly enhance solubility in polar solvents like water.
  • Molecular Polarity: The overall polarity of the compound is affected by the pyridine and furan rings, which can impact interaction with solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the carboxylic acid can also facilitate solubility in water and other polar solvents.

As a general observation, aromatic compounds with polar functional groups often exhibit enhanced solubility in water, while their overall solubility can vary depending on the solvent used:

  • High Solubility: In polar solvents (e.g., methanol, ethanol)
  • Moderate Solubility: In mixed solvent systems
  • Poor Solubility: In non-polar solvents (e.g., hexane, toluene)

In conclusion, while 5-(3-pyridylmethyl)benzofuran-2-carboxylic acid is likely to exhibit notable solubility in polar solvents, the specific conditions, such as temperature and concentration, can further influence its solubility behavior.

Interesting facts

Interesting Facts about 5-(3-pyridylmethyl)benzofuran-2-carboxylic Acid

5-(3-pyridylmethyl)benzofuran-2-carboxylic acid is a fascinating compound that showcases the intricate relationship between structure and function in organic chemistry. Here are some intriguing points about this compound:

  • Hybrid Structure: This compound features a unique combination of a benzofuran moiety and a pyridine ring. Such hybrid structures are often pivotal in the development of biologically active molecules.
  • Pharmacological Potential: Compounds containing both benzofuran and pyridine are known to exhibit a variety of biological activities, including antibacterial, antifungal, and anti-cancer properties. This makes 5-(3-pyridylmethyl)benzofuran-2-carboxylic acid a compound of interest in medicinal chemistry.
  • Applications in Synthesis: The carboxylic acid functional group in this compound allows it to participate in diverse chemical reactions, such as esterification and amidation, which are essential in designing new pharmaceuticals.
  • Research Interest: Scientists are increasingly interested in studying this compound due to its potential application in developing drugs targeting various diseases, particularly those involving the central nervous system.

As we explore the properties and reactions of 5-(3-pyridylmethyl)benzofuran-2-carboxylic acid, we not only deepen our understanding of organic chemistry but also uncover possibilities for innovation in drug discovery and development.

In the words of Aristotle, "All men by nature desire to know." This intrinsic desire drives scientists to study compounds like this one, revealing the complexities and wonders of chemical science.

Synonyms
furegrelate
85666-24-6
Furegrelato
Furegrelate [INN]
Furegarelatum
5-(pyridin-3-ylmethyl)benzofuran-2-carboxylic acid
5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylic acid
Furegarelatum [Latin]
Furegrelato [Spanish]
UNII-KX4D9BZA6X
KX4D9BZA6X
2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-
U-63557A (free acid)
DTXSID7046960
5-(3-pyridylmethyl)-2-benzofurancarboxylic acid
Furegarelatum (Latin)
5-(3-Pyridinylmethyl)-2-benzofurancarboxylic acid
5-(3-PYRIDYLMETHYL)-2-BENZOFURANCARBOXYLATE
UNII-4F11B27M90
U 63557A
furegrelatum
5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate
Spectrum_000041
Spectrum2_001444
Spectrum3_000786
Spectrum4_000793
Spectrum5_001141
Lopac0_000515
BSPBio_002492
KBioGR_001266
KBioSS_000421
DivK1c_000255
SPBio_001307
CHEMBL1204948
DTXCID5026960
SCHEMBL10953582
KBio1_000255
KBio2_000421
KBio2_002989
KBio2_005557
KBio3_001712
CHEBI:103833
NINDS_000255
EX-A10836
AKOS030555586
SDCCGSBI-0050499.P003
IDI1_000255
TS-07811
HY-106080
CS-0024808
NS00125976
BRD-K55529781-236-02-0
BRD-K55529781-236-03-8
Q27180995