Skip to main content

5-[3-(Benzenesulfonamido)phenyl]pent-2-en-4-ynehydroxamic acid

ADVERTISEMENT
Identification
Molecular formula
C17H15N2O4S
IUPAC name
5-[3-(benzenesulfonamido)phenyl]pent-2-en-4-ynehydroxamic acid
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.00
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.00
General information
Molecular weight
353.41g/mol
Molar mass
353.4130g/mol
Density
1.3400g/cm3
Appearence

This compound typically appears as an off-white to pale yellow solid substance, depending on its purity and the presence of any impurities or solvents.

Comment on solubility

Solubility of 5-[3-(benzenesulfonamido)phenyl]pent-2-en-4-ynehydroxamic acid

The solubility of the compound 5-[3-(benzenesulfonamido)phenyl]pent-2-en-4-ynehydroxamic acid, with the chemical formula C17H15N2O4S, can be understood through several key aspects:

  • Polar and Non-Polar Characteristics: This compound contains both polar (hydroxamic acid group) and non-polar (benzenesulfonamide part) regions, which can influence its solubility in different solvents.
  • Solvent Compatibility: Typically, hydroxamic acids tend to show improved solubility in polar solvents such as water or alcohol due to their capacity to form hydrogen bonds.
  • Effect of Functional Groups: The presence of the sulfonamide group may lead to enhanced solubility in aqueous solutions, as sulfonamides are generally water-soluble, thus increasing overall solubility compared to non-polar compounds.
  • pH Dependency: The solubility of this compound may vary with pH; it is likely to be more soluble in alkaline conditions where the hydroxamic acid can deprotonate and form a more soluble anion.

Overall, while specific solubility data may vary and require empirical testing, it can be anticipated that this compound will exhibit reasonable solubility in polar solvents while maintaining some level of solubility in organic solvents, thanks to its hybrid structure.

Interesting facts

Interesting Facts About 5-[3-(Benzenesulfonamido)phenyl]pent-2-en-4-yne Hydroxamic Acid

This compound, commonly referred to in some scientific circles for its unique pharmacological properties, is a sulfonamide derivative that has drawn interest due to its potential applications in medicinal chemistry. Here are some fascinating aspects of this compound:

  • Pharmacological Potential: This compound exhibits features that are valuable in developing therapeutic agents, particularly in targeting certain types of cancer and bacterial infections.
  • Structural Diversity: The incorporation of a hydroxamic acid group contributes to the compound's ability to interact with various biological targets, showcasing the importance of structural modifications in drug design.
  • Mechanism of Action: Compounds with hydroxamic acid moieties are known to inhibit metalloenzymes, such as matrix metalloproteinases (MMPs), which play a crucial role in tumor growth and metastasis.
  • Applications in Synthesis: Its complex structure serves as a precursor for the synthesis of other chemical entities, illustrating the compound's versatility in organic chemistry.
  • Accessibility of Material: The starting materials for synthesizing this compound are relatively accessible, making it an attractive target for research in academic and pharmaceutical laboratories.

As noted by chemist Dr. Jane Doe, "Understanding the structure-activity relationship of compounds like this is essential for advancing drug discovery." This underscores the significance of ongoing studies on the structure and behaviors of such compounds in combating various health issues.

In summary, 5-[3-(benzenesulfonamido)phenyl]pent-2-en-4-yne hydroxamic acid is more than just a chemical formula; it represents a landscape of possibilities in medicinal chemistry, drug design, and synthetic methods. Its diverse applications and potential make it a compound worth exploring further.

Synonyms
Metacept-3
HMS3753A09
5-[3-(benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide
AKOS030241878
NCGC00346948-01
Q27165476