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Adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(2,6-dioxo-3,7-dihydropurin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

Solid at room temperature. AMP is a stable, solid powder that remains in its solid state under normal conditions of temperature and pressure.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.1000g/cm3
Appearence

Adenosine monophosphate (AMP) is typically found as a white crystalline powder. It is a nucleotide that appears as a fine, white, hygroscopic powder with good solubility in water.

Comment on solubility

Solubility of [5-(2,6-dioxo-3,7-dihydropurin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The solubility of the compound C10H14N5O7P is influenced by its unique structural characteristics and functional groups.

Factors Affecting Solubility:

  • Polarity: The presence of multiple hydroxyl groups (–OH) and a phosphate group (–PO4) suggests that this compound may be polar, which generally enhances solubility in polar solvents (e.g., water).
  • Hydrogen Bonding: The ability of the hydroxyl and phosphate functional groups to form hydrogen bonds can significantly increase solubility in aqueous solutions.
  • Ionization: Given the dihydrogen phosphate part of its structure, the compound can undergo ionization which may further increase its solubility in water, potentially dissolving more readily due to the formation of charged species.

As a result of these structural features, it can be anticipated that the compound is likely to be soluble in water, especially at physiological pH levels. However, precise solubility values would require empirical experimentation to confirm, as solubility can vary based on concentration, temperature, and the presence of other solutes.

Conclusion:

In summary, the interaction of functional groups within [5-(2,6-dioxo-3,7-dihydropurin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate suggests a favorable solubility profile in polar solvents, particularly in aqueous media.

Interesting facts

Interesting Facts about [5-(2,6-dioxo-3,7-dihydropurin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This compound showcases an intriguing blend of organic chemistry and biochemistry, predominantly due to its structural connections with purines, which are vital components in nucleic acids, like DNA and RNA. Below are some engaging insights that highlight the significance and unique characteristics of this compound:

  • Bioactive Potential: The presence of the purine moiety indicates potential bioactivity, suggesting that this compound could exhibit interactions within biological systems, possibly affecting cellular signaling processes.
  • Phosphate Group: The dihydrogen phosphate part of the compound is essential in energy transfer reactions, as seen in ATP (adenosine triphosphate). This highlights the compound’s potential role in energy metabolism.
  • Natural Analogues: The structural features of this compound can be likened to various natural products and pharmaceuticals, inspiring research into its pharmacological applications, particularly in the fields of anti-viral and anti-cancer agents.
  • Complex Structure: The elaborate structure featuring multiple functional groups opens up fascinating pathways for synthetic chemists to explore novel synthesis techniques and reaction pathways.
  • Research Interest: Compounds of this nature typically attract interest in medicinal chemistry research, with scientists seeking to elucidate their mechanisms of action and therapeutic potential through advanced methods such as molecular modeling and computational chemistry.

In summary, [5-(2,6-dioxo-3,7-dihydropurin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate serves as a fascinating subject of study, reflecting the interconnectedness of structural chemistry with biological functions and medicinal applications. As a chemistry student or a researcher, delving into the complexities of such compounds could be both challenging and rewarding!

Synonyms
PD124892