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Fenofibric acid

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Identification
Molecular formula
C17H18O4
CAS number
42017-89-0
IUPAC name
5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid
State
State

At room temperature, Fenofibric acid is a solid substance.

Melting point (Celsius)
116.50
Melting point (Kelvin)
389.70
Boiling point (Celsius)
396.40
Boiling point (Kelvin)
669.50
General information
Molecular weight
318.41g/mol
Molar mass
318.4050g/mol
Density
1.0856g/cm3
Appearence

Fenofibric acid typically appears as a white to yellow solid compound. It is crystalline in nature and is not known to have any distinctive odor.

Comment on solubility

Solubility of 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid

The solubility of 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid (C17H18O4) is influenced by its chemical structure, which features a hydrophobic aromatic ring and a carboxylic acid functional group. This unique combination creates interesting solubility characteristics:

  • Hydrophobic Characteristics: The presence of the bulky 2,5-dimethylphenoxy group contributes to hydrophobic interactions, making the compound less soluble in polar solvents.
  • Polar Functional Groups: The carboxylic acid group (-COOH) can form hydrogen bonds with water, which can increase solubility in polar environments.
  • pH Dependency: The solubility of the compound may vary with pH. In acidic conditions, it remains primarily in its neutral form, while in basic conditions, it can ionize and increase solubility due to enhanced interactions with water.

Overall, the complex balance between hydrophobic and hydrophilic characteristics in 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid means it is likely to exhibit limited solubility in water but may dissolve better in organic solvents or at certain pH levels. Therefore, when considering its applications or reactions, it is essential to account for these solubility traits.

Interesting facts

Interesting Facts About 5-(2,5-Dimethylphenoxy)-2,2-dimethyl-pentanoic Acid

5-(2,5-Dimethylphenoxy)-2,2-dimethyl-pentanoic acid is a fascinating chemical compound with several noteworthy attributes that appeal to both scientists and chemistry enthusiasts. Here are some key insights:

  • Structural Complexity: This compound features a unique structure that includes a dimethylphenoxy group and a pentanoic acid moiety, making it an excellent example of how diverse chemical architectures can influence compound properties and reactivity.
  • Potential Applications: Compounds like this are often explored for their potential as intermediates in the synthesis of pharmaceuticals and agrochemicals. Understanding their reactivity can lead to the development of new therapeutic agents.
  • Research Interest: Its structural diversity and functional properties make it a subject of interest in various fields, including medicinal chemistry and materials science, leading to ongoing research about its biological activities.
  • Environmental Impact: Investigating the biodegradability and eco-toxicity of such compounds is crucial, especially in the context of environmental chemistry, where the sustainability of chemical compounds is becoming paramount.

Overall, studying 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid not only enhances our understanding of organic chemistry but also has the potential to contribute to innovative solutions in health and environmental sciences. As with many chemical compounds, the journey from molecular design to real-world application is a testament to the intricate nature of chemistry.

Synonyms
gemfibrozil
25812-30-0
5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
Lopid
Jezil
Lipur
Cholespid
Fibratol
Fibrocit
Gemfibril
Gemfibromax
Gemfibrozilo
Gemlipid
Hipolixan
CI-719
Gemfibrozilum
Renabrazin
Clearol
Elmogan
Fetinor
Gemnpid
Innogen
Ipolipid
Lanaterom
Lifibron
Lipigem
Lipizyl
Micolip
Normolip
Progemzal
Reducel
Regulip
Sinelip
Synbrozil
Taborcil
Tentroc
Brozil
Gozid
Hidil
Lipira
Gemd
Gevilon Uno
WL-Gemfibrozil
Gen-Fibro
Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
Low-Lip
Gem-S
Lipozid
2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure
Gemfibrozilum [INN-Latin]
Gemfibrozilo [INN-Spanish]
CCRIS 318
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
Decrelip
EINECS 247-280-2
MFCD00079335
NSC-757024
BRN 1881200
Gemfibrozil (Lopid)
Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-
Bolutol
CHEBI:5296
Apo-Gemfibrozil
DTXSID0020652
UNII-Q8X02027X3
HSDB 7735
Gemfibrozil (Standard)
Gemfibrosil
Lipazil
Litarek
Trialmin
Ausgem
Pilder
CHEMBL457
Q8X02027X3
DTXCID20652
MLS000028421
Gemfibrozil [USAN:USP:INN:BAN]
2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid
NSC 757024
5-[(2,5-dimethylphenyl)oxy]-2,2-dimethylpentanoic acid
NCGC00016794-09
SMR000058393
Genlip
CAS-25812-30-0
GEMFIBROZIL (IARC)
GEMFIBROZIL [IARC]
Gemfibrozilum (INN-Latin)
Gemfibrozilo (INN-Spanish)
GEMFIBROZIL (MART.)
GEMFIBROZIL [MART.]
GEMFIBROZIL (USP-RS)
GEMFIBROZIL [USP-RS]
2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID
GEMFIBROZIL (EP MONOGRAPH)
GEMFIBROZIL [EP MONOGRAPH]
Innogem
Gemcor
GEMFIBROZIL (USP MONOGRAPH)
GEMFIBROZIL [USP MONOGRAPH]
Gemfibrozil (USAN:USP:INN:BAN)
CI 719
Lopid (TN)
TEVA-A
SR-01000000056
Gemfibrozil (JAN/USP/INN)
Gemfibrozil,(S)
4TX
Prestwick_637
dimethylpentanoic acid
Spectrum_000825
CPD000058393
GEMFIBROZIL [MI]
114413-98-8
Opera_ID_1658
Prestwick0_000214
Prestwick1_000214
Prestwick2_000214
Prestwick3_000214
Spectrum2_001097
Spectrum3_000440
Spectrum4_000562
Spectrum5_000750
Spectrum5_001991
GEMFIBROZIL [INN]
GEMFIBROZIL [JAN]
GEMFIBROZIL [HSDB]
GEMFIBROZIL [USAN]
GEMFIBROZIL [VANDF]
SCHEMBL4813
BSPBio_000227
BSPBio_002060
GEMFIBROZIL [WHO-DD]
KBioGR_000964
KBioSS_001305
MLS001055364
MLS006011850
DivK1c_000138
SPECTRUM1500313
SPBio_001174
SPBio_002148
5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid
BPBio1_000251
GTPL3439
YSSJ5501
Gemfibrozil, analytical standard
Cl-719
HMS500G20
HY-B0258R
KBio1_000138
KBio2_001305
KBio2_003873
KBio2_006441
KBio3_001280
C10AB04
GEMFIBROZIL [ORANGE BOOK]
Gemfibrozil for system suitability
NINDS_000138
HMS1568L09
HMS1920B07
HMS2090K14
HMS2091H11
HMS2095L09
HMS2230H24
HMS3259M12
HMS3655C06
HMS3712L09
Pharmakon1600-10500313
5-(2,5-dimethylphenoxy)-2,2-
BCP08437
HY-B0258
Tox21_110613
Tox21_201997
Tox21_302784
BBL010807
BDBM50110590
CCG-40111
DL-414
NSC757024
s1729
STK618740
AKOS001606691
Tox21_110613_1
AB03034
AC-4225
DB01241
FD23652
KS-5192
NC00565
IDI1_000138
NCGC00016794-01
NCGC00016794-02
NCGC00016794-03
NCGC00016794-04
NCGC00016794-05
NCGC00016794-06
NCGC00016794-07
NCGC00016794-08
NCGC00016794-10
NCGC00016794-11
NCGC00016794-13
NCGC00016794-14
NCGC00022722-03
NCGC00022722-04
NCGC00022722-05
NCGC00022722-06
NCGC00022722-07
NCGC00256601-01
NCGC00259546-01
SY052512
Gemfibrozil 100 microg/mL in Acetonitrile
SBI-0051391.P003
AB00052003
CS-0694895
G0368
NS00010281
SW196802-3
2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaure
EN300-97098
C07020
D00334
D83091
AB00052003-15
AB00052003-16
AB00052003_17
AB00052003_18
Q384295
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaure
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeric Acid
5-(2,5-dimethyphenoxy)-2,2-dimethylpentanoic acid
SR-01000000056-3
SR-01000000056-4
SR-01000000056-6
SR-01000000056-7
2,2-Dimethyl-5-(2,5-dimethylphenoxy)-pentanoic acid
BRD-K11129031-001-05-1
BRD-K11129031-001-26-7
BRD-K11129031-001-27-5
Z1259021151
Gemfibrozil, British Pharmacopoeia (BP) Reference Standard
Gemfibrozil, European Pharmacopoeia (EP) Reference Standard
Gemfibrozil, United States Pharmacopeia (USP) Reference Standard
Gemfibrozil, Pharmaceutical Secondary Standard; Certified Reference Material
5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid;CI-7;Decrelip;Gemfibrozil
Gemfibrozil for system suitability, European Pharmacopoeia (EP) Reference Standard
2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid, 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid, 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic aci
247-280-2