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Cytidine monophosphate

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Identification
Molecular formula
C9H14N3O8P
CAS number
63-37-6
IUPAC name
[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
195.50
Melting point (Kelvin)
468.65
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
323.18g/mol
Molar mass
323.1810g/mol
Density
2.2000g/cm3
Appearence

Cytidine monophosphate typically appears as a white, crystalline powder.

Comment on solubility

Solubility Overview of [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (C9H14N3O8P)

The solubility of the compound [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate can be influenced by various factors, reflecting its complex structure. Here, we break down the solubility characteristics:

  • Polarity: The presence of multiple -OH (hydroxyl) groups and a -PO4 group suggest high polarity, which generally enhances solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the hydroxyl and phosphate groups can facilitate interactions with water, thereby improving solubility.
  • Structural Features: The fused pyrimidine ring might impact the overall solubility, as cyclic and aromatic structures often exhibit distinct solubility behavior.

It’s crucial to note that while the structural elements can indicate solubility trends, the actual solubility must be substantiated through experimental data. Typically, compounds like this may exhibit:

  1. High solubility in aqueous environments.
  2. Variable solubility in organic solvents.

Understanding these solubility properties is essential for applications in pharmaceuticals and biochemistry, where solubility can greatly affect bioavailability and overall effectiveness.

Interesting facts

Interesting Facts about [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This compound, a complex organic molecule, demonstrates the fascinating interplay between organic chemistry and biochemistry. Here are some noteworthy insights:

  • Biochemical Relevance: This compound may serve important roles in biochemical pathways, particularly those involving nucleic acids and phosphate group interactions. Its structure suggests functionality in processes reminiscent of *nucleotide synthesis*.
  • Synthetic Potential: The intricate stereochemistry within its framework provides a wealth of possibilities for synthetic chemists. Researchers often explore such compounds for their potential as *drug candidates* or *biological probes*.
  • Structural Complexity: The presence of both a pyrimidine ring and a tetrahydrofuran moiety indicates how natural products often exhibit hybrid structures, which may lead to unique biological activities or interactions with biomolecules.
  • Phosphate Chemistry: The inclusion of dihydrogen phosphate groups emphasizes the compound's significance in *energy transfer* processes, usually linked with ATP (adenosine triphosphate) in metabolic activities.
  • Research Implications: Given its structural components, this compound could be a subject of interest in *pharmacology*, particularly in designing inhibitors or modulators acting on *enzymes* related to nucleotide metabolism.

As research continues, compounds like this one serve not only as fascinating subjects of study in their own right but also as gateways to understanding the complexities of biological systems.

Synonyms
28086-43-3
[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
POLYURIDYLIC ACID POT. SALT, LYOPH., MR
Uridine 5'-monophosphate;Uridylic acid, 5'-Uridylic acid, Uridine phosphate, 5'-UMP, Uridine 5'-phosphoric acid
27416-86-0
1-(5-o-phosphonopentofuranosyl)-2,4(1h,3h)-pyrimidinedione
uridine-5-monophosphate
Diquafosol Impurity 16
uridine-5'-monophos-phate
SCHEMBL157645
DTXSID40861596
CHEBI:177578
Uridine 5'-monophosphate, >=98%
NSC224963
NA16509
NSC-224963
SY076340
DS-015687
NS00009556
Q414932
SR-01000883749
Uridine 5 inverted exclamation mark -Monophosphate
SR-01000883749-1
1-(5-O-Phosphonopentofuranosyl)pyrimidine-2,4(1H,3H)-dione
6-[(Z)-(methylhydrazinylidene)methyl]-1h-pyrimidine-2,5-dione
[(2S,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
1-(5-O-Phosphono-b-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione;Uracil arabinonucleoside 5'-phosphate