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Uridine diphosphate glucose

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Identification
Molecular formula
C15H24N2O17P2
CAS number
58-98-0
IUPAC name
[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] (3,4,5-trihydroxytetrahydropyran-2-yl) hydrogen phosphate
State
State

At room temperature, uridine diphosphate glucose is a solid that requires careful storage to prevent degradation, especially in humid conditions.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
566.30g/mol
Molar mass
0.0000g/mol
Density
1.8000g/cm3
Appearence

Uridine diphosphate glucose is typically an off-white to white solid. It is hygroscopic, meaning it readily absorbs moisture from the environment. In most laboratory settings, it is found as a crystalline powder.

Comment on solubility

Solubility of [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl (3,4,5-trihydroxytetrahydropyran-2-yl) hydrogen phosphate

The compound with the complex name [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl (3,4,5-trihydroxytetrahydropyran-2-yl) hydrogen phosphate, represented by its chemical formula C15H24N2O17P2, exhibits intriguing solubility characteristics.

Solubility factors for this compound can be addressed as follows:

  • Polar Nature: The presence of multiple hydroxyl (–OH) groups contributes to its polar nature, which typically enhances solubility in polar solvents such as water.
  • Hydrophilic Characteristics: As a phosphate-containing compound, it may show effective interaction with water molecules, facilitating solvation.
  • Effect of Hydrogen Bonding: The ability to form hydrogen bonds due to the –OH and –NH groups can significantly impact its solubility in various solvents.
  • Complex Formation: This compound could potentially form complexes with metal ions or other solutes, influencing solubility further.

As a general observation, while many organic molecules with such complex structures tend to possess moderate to high solubility in aqueous solutions, the exact solubility of this compound would depend on various conditions such as pH and temperature. It should be noted, however, that while polar interactions favor solubility, steric hindrance and molecular size can present challenges.

In conclusion, one could anticipate that the solubility of this compound is likely to be favorable in aqueous environments—but assessing this accurately would require experimental verification.

Interesting facts

Interesting Facts about [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] (3,4,5-trihydroxytetrahydropyran-2-yl) hydrogen phosphate

This complex compound is an intriguing example of how organic chemistry can intertwine with biological systems, particularly in the realm of nucleotide analogs. Here are some engaging facts about this remarkable molecule:

  • Nucleotide Influence: The structure of this compound suggests a potential role in mimicking natural nucleotides, which are the foundational building blocks of RNA and DNA. This resemblance is critical in designing drugs that can interfere with nucleic acid synthesis.
  • Phosphate Group: The incorporation of hydroxy-phosphoryl groups in the compound indicates its possible function in biological signaling processes. Phosphate groups play a vital role in energy transfer and storage, as seen in adenosine triphosphate (ATP).
  • Applications in Medicinal Chemistry: Compounds like this one are being explored for their potential therapeutic applications, especially in the treatment of diseases such as cancer and viral infections, where nucleotide synthesis can be a target.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the tetrahydrofuran and tetrahydropyran rings influence biological activity can guide the development of more effective drugs. SAR studies are essential for optimizing compound efficacy and minimizing toxicity.
  • Research Opportunities: The unique structural features provide ample ground for research. Chemists can explore methods of synthesis, thereby advancing techniques in organic synthesis, particularly in incorporating complex functional groups.

In summary, this compound is more than just a chemical formula; it represents a bridge between chemistry and biology, holding the potential for significant advancements in pharmaceutical sciences. It exemplifies the intricate beauty and complexity of molecular design in pursuit of innovative therapeutic solutions.

Synonyms
UDP-L-arabinose
UDP-xylose
3616-06-6
UDP-B-L-ARABINOSE
[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] (3,4,5-trihydroxyoxan-2-yl) hydrogen phosphate
[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-(3,4,5-trihydroxyoxan-2-yl)oxy-phosphoryl]oxy-phosphinic acid
UDP-Xyl
Diphosphate Xylose, Uridine
UDP-|A-L-Arabinose
MFCD15145137
MFCD32644832
SY286888
SY286975