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Cytidine monophosphate

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Identification
Molecular formula
C9H14N3O8P
CAS number
63-37-6
IUPAC name
[5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, cytidine monophosphate is a solid compound. It is stable under standard laboratory conditions.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
323.19g/mol
Molar mass
323.1880g/mol
Density
0.4000g/cm3
Appearence

Cytidine monophosphate appears as a white, crystalline powder. It is commonly used in biochemical research and has a characteristic solid form.

Comment on solubility

Solubility of [5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The compound [5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate, with the chemical formula C9H14N3O8P, presents unique solubility characteristics that are worth noting.

Factors Influencing Solubility

Several factors affect the solubility of this compound, including:

  • Polarity: The presence of multiple polar functional groups, such as hydroxyl and phosphate moieties, suggests it may have a higher solubility in polar solvents, particularly water.
  • Hydrogen bonding: The capability to form hydrogen bonds with water molecules likely enhances its solubility.
  • Molecular structure: The complex bicyclic structure adds to the intriguing behavior of solubility, potentially affecting its interaction dynamics in solution.

General Insights

While detailed empirical data might be limited, it can be anticipated that the solubility of this compound is:

  • **Moderate to high in aqueous solutions**, due to the presence of the dihydrogen phosphate group.
  • **Variable in organic solvents**, largely depending on the solvent’s polarity and hydrogen-bonding ability.

In conclusion, understanding the solubility behavior of [5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate can be essential for its applications in various chemical processes, particularly in pharmaceutical formulations where bioavailability is crucial. The compound's ability to dissolve in relevant solvents will likely influence its efficacy and utility in biological systems.

Interesting facts

Interesting Facts about [5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This intriguing compound is a derivative of nucleobases, showcasing the fascinating interplay between organic chemistry and biochemistry. It is primarily known for its potential applications in medicinal chemistry and pharmaceuticals. Here are some fascinating insights about it:

  • Structural Complexity: The compound features a unique tetrahydrofuran ring fused with a pyrimidine derivative, marking it as an interesting target for synthetic organic chemists aiming to develop novel therapies.
  • Biological Relevance: The presence of a phosphate group indicates a potential role in cellular signaling pathways, which is crucial for cellular communication and regulation.
  • Potential as an Anticancer Agent: Research suggests that derivatives of pyrimidine have shown efficacy in inhibiting various types of cancer cell lines, paving the way for future drug development.
  • Synthesis Challenges: The construction of this compound may involve multi-step synthetic pathways, often necessitating the mastery of several organic chemistry techniques such as functional group interconversions and regioselective reactions.
  • Versatile Reactivity: The hydroxyl group on the tetrahydrofuran moiety is likely to participate in various chemical reactions, making this compound amenable for modifications to enhance its pharmacological properties.

In summary, [5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate is more than just a chemical formula; it represents a significant intersection of synthetic and medicinal chemistry, holding potential for groundbreaking contributions to therapeutic sciences.

Synonyms
1-(2-deoxy-5-o-phosphonopentofuranosyl)pyrimidine-2,4(1h,3h)-dione
deoxyuridine-monophosphate
SCHEMBL21941035
SCHEMBL25024676
DTXSID30862491
JSRLJPSBLDHEIO-UHFFFAOYSA-N
((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
PD040795
[(2S,5S)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate