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Uridine monophosphate

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Identification
Molecular formula
C9H13N2O9P
CAS number
58-97-9
IUPAC name
[5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, uridine monophosphate is typically found as a solid. It is stable under normal temperature and pressure conditions.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
725.00
Boiling point (Kelvin)
998.15
General information
Molecular weight
324.18g/mol
Molar mass
324.1810g/mol
Density
2.1009g/cm3
Appearence

Uridine monophosphate (UMP) is a white to off-white crystalline powder. It is an essential pyrimidine nucleotide with a ribofuranoside as its sugar moiety, commonly found in nucleic acids.

Comment on solubility

Solubility Overview

The compound [5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate, with the chemical formula C9H13N2O9P, presents an intriguing case when discussing its solubility characteristics. Understanding its solubility is essential for various applications, particularly in pharmacology and biochemistry.

Solubility Characteristics

This compound exhibits several factors that can impact its solubility:

  • Polarity: The presence of multiple hydroxyl (–OH) groups and a phosphate moiety enhances its polarity, which generally facilitates solubility in polar solvents, such as water.
  • Hydrogen Bonding: The functional groups are prone to forming hydrogen bonds, which can significantly increase solubility in aqueous environments.
  • pH Dependence: Given the dihydrogen phosphate group, the solubility can vary with changes in pH, potentially affecting its ionization state and solubility profile.
  • Temperature Effects: As is common with many compounds, solubility may increase with temperature, suggesting that higher temperatures could enhance dissolution rates.

General Insights

In summary, the solubility of this compound likely demonstrates a favorable profile in polar solvents, consistent with its complex molecular structure. As you explore the implications of these solubility properties, consider that:

  • "Solubility is *key* in determining the bioavailability of pharmaceutical compounds."
  • The interplay between solubility and activity can guide the development of effective therapeutic agents.

Investigation into specific solubility metrics, such as saturation concentration and solubility product constants, would further elucidate its potential applications.

Interesting facts

Interesting Facts about [5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This complex compound is an intriguing example of the intersection between organic chemistry and biochemistry. Known for its structural diversity, it contains a pyrimidine ring, a tetrahydrofuran moiety, and a phosphate group. Each part of its structure contributes unique properties that have piqued the interest of scientists.

Key Features

  • Pyrimidine Component: The presence of a pyrimidine ring is noteworthy because compounds derived from this structure often demonstrate important biological activities and can be found in many pharmaceuticals.
  • Phosphate Group: Phosphate groups play a crucial role in energy transfer, signaling pathways, and molecular biology, particularly in the form of ATP and DNA.
  • Tetrahydrofuran Structure: The incorporation of a tetrahydrofuran ring adds an intriguing element by enhancing solubility and reactivity in various organic reactions.

This compound can also be classified under prodrugs, which are administered in an inactive form before being metabolized into active pharmacological agents in the body. Its design hints at potential applications in developing novel therapies to target various diseases. As one chemist aptly stated, "Innovation in drug design often starts with reimagining existing frameworks!"

Research Potential

Researchers are enthusiastic about exploring the following aspects:

  • Efficacy in targeting specific biological pathways.
  • Potential role in molecular mechanisms of disease.
  • Insights into pharmacokinetics and bioavailability.

Overall, this compound exemplifies the sophistication of modern chemistry, where the combination of diverse functional groups can lead to remarkable properties and applications. With ongoing research and exploration, its full potential may illuminate pathways to innovative therapeutic strategies.

Synonyms
[5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
SCHEMBL10133483
(5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate