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5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine

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Identification
Molecular formula
C14H12ClNS
CAS number
161798-01-2
IUPAC name
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
State
State

The compound exists as a solid at room temperature.

Melting point (Celsius)
92.50
Melting point (Kelvin)
365.70
Boiling point (Celsius)
334.20
Boiling point (Kelvin)
607.30
General information
Molecular weight
235.77g/mol
Molar mass
235.7330g/mol
Density
0.9088g/cm3
Appearence

The compound is typically a crystalline solid at room temperature and may present as a white to off-white powder depending on purity and specific synthesis methods used. Being a crystalline substance, it might exhibit a shiny and granular texture.

Comment on solubility

Solubility of 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine

The solubility of 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine (C14H12ClNS) can be quite interesting to discuss, as it plays a significant role in its utility and application in various fields.


This compound's solubility characteristics can typically be influenced by several factors:

  • Polarity: The presence of the chlorophenyl and thieno groups can modulate its polarity, which is crucial in determining its solubility in different solvents.
  • Hydrogen Bonding: The nitrogen atom present in the thienopyridine structure may allow for the formation of hydrogen bonds, which can enhance solubility in polar solvents.
  • Solvent Choice: Solubility is generally higher in organic solvents such as dichloromethane or ethanol compared to water, given the compound's hydrophobic characteristics.

As a general insight, while many thienopyridine compounds are often found to be poorly soluble in water, it is essential to conduct thorough solubility tests in specific solvents to determine the most appropriate conditions for use. In the words of chemists, "Solubility is the gateway to understanding reactivity and application!"

When considering practical applications, understanding the solubility behavior of this compound can significantly aid in formulating effective drug delivery systems, highlighting the importance of tailored solubility in pharmacological contexts.

Interesting facts

Interesting Facts about 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine

This intriguing compound, commonly referred to as a thienopyridine, is part of a larger class of versatile organic molecules that play significant roles in medicinal chemistry.

Key Characteristics

  • Structural Diversity: The thienopyridine framework blends the properties of both thiophene and pyridine, creating a unique scaffold that can be modified for various biological activities.
  • Biological Relevance: Compounds in this group often exhibit antidepressant, analgesic, and anti-anxiety effects due to their ability to interact with neurotransmitter systems in the brain.
  • 2-Chlorophenyl Group: The presence of the 2-chlorophenyl moiety can enhance the lipophilicity and bioavailability of the compound, which is crucial for its pharmacological efficacy.

Applications in Research

Researchers continue to explore the potential of this compound in drug design, particularly for central nervous system disorders. With modifications, derivatives can be created that may have improved selectivity and potency. The compound serves as a fascinating example of how small structural changes can lead to significant variations in biological activity.

Quote to Inspire

As the famous chemist Linus Pauling once said, “The best way to have a good idea is to have a lot of ideas.” The study of thienopyridines reflects this ethos, showcasing how diverse functional groups bring new possibilities in pharmacological innovation.

In conclusion, 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine stands as a testament to the creativity and potential within organic synthesis, inviting chemists to unlock its secrets for the benefit of human health.

Synonyms
ticlopidine
55142-85-3
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Ticlopidina
Ticlopidinum
Ticlopidin-Puren
PCR 5332
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
Ticlopidina [INN-Spanish]
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
EINECS 259-498-5
OM90ZUW7M1
Ticlopidine (INN)
BRN 1216802
CHEBI:9588
DTXSID5023669
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Thieno(3,2-c)pyridine, 4,5,6,7-tetrahydro-5-((2-chlorophenyl)methyl)-
DTXCID903669
5-[(2-chlorophenyl)methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine
Thieno[3,2-c]pyridine, 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-
PCR 5332; Ticlid; Ticlop;Tiklyd
NCGC00016872-06
TICLOPIDINE [INN]
Ticlopidinum (INN-Latin)
Thieno(3,2-c)pyridine, 5-((2-chlorophenyl)methyl)-4,5,6,7-tetrahydro-
Ticlopidina (INN-Spanish)
Ticlopidine [INN:BAN]
SMR000641861
CAS-55142-85-3
Ticlopidin-Puren (TN)
5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
MFCD00661081
Ticlopidine (Standard)
TICLOPIDINE [MI]
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
CHEMBL833
TICLOPIDINE [VANDF]
SCHEMBL4204
BIDD:PXR0169
BSPBio_000173
TICLOPIDINE [WHO-DD]
MLS001201825
MLS006011439
SPBio_002094
BPBio1_000191
GTPL7307
BDBM85509
B01AC05
HMS2089I18
HMS2962E14
BCP25528
NSC_5472
Tox21_110658
BBL028843
STK589340
AKOS005511613
Tox21_110658_1
DB00208
DS-6623
HY-100386R
NCGC00016872-01
NCGC00016872-02
NCGC00016872-03
NCGC00016872-04
NCGC00016872-05
NCGC00016872-07
NCGC00016872-09
NCGC00016872-10
NCGC00016872-12
NCGC00024361-04
AC-15204
AC-38059
DA-68188
SBI-0206813.P001
CAS-53885-35-1
CAS_55142-85-3
HY-100386
UNM-0000345023
CS-0018717
NS00010201
S0721
C07140
D08594
EN300-1692883
L001108
Q420571
BRD-K00603606-003-03-4
BRD-K00603606-003-13-3
BRD-K00603606-003-23-2
BRD-K00603606-003-24-0
Z231745614
5-(2-chlorobenzyl)-4,5,6,7tetrahydrothieno[3,2-c]pyridine
5-(O-Chlorobenzyl)-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4H,6H,7H-thieno[3,2-c]pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine #
259-498-5