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Adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, adenosine monophosphate is typically found as a solid. It is relatively stable and soluble in water.

Melting point (Celsius)
-1.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
272.15
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.3304g/cm3
Appearence

Adenosine monophosphate (AMP) typically appears as a white, crystalline powder when in its solid state. It is a mononucleotide that is composed of a phosphate group, the sugar ribose, and the nucleobase adenine.

Comment on solubility

Solubility of [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The solubility of the compound [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (C10H14N5O7P) can be quite intriguing, given its complex molecular structure. An understanding of its solubility can be derived from the following key factors:

  • Polar Functional Groups: The presence of multiple hydroxyl (-OH) groups and a phosphate group contributes to the overall polarity of the molecule, enhancing its potential solubility in water.
  • Hydrogen Bonding: The hydroxyl groups can engage in hydrogen bonding with water molecules, which likely increases solubility. This interaction is crucial as it allows the compound to dissolve more readily in aqueous solutions.
  • Electrostatic Interactions: The negatively charged phosphate group can interact with positively charged species or ions in solution, further promoting solubility.
  • Specific Solvent Effects: While this compound is expected to be soluble in polar solvents like water, its solubility may vary in organic solvents based on their own polarities. For example, it may be less soluble in non-polar solvents.

In essence, we could summarize the solubility characteristics of this compound as follows:

  1. Highly soluble in polar solvents (e.g., water).
  2. Limited or negligible solubility in non-polar solvents.

To encapsulate, the solubility of [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate is significantly influenced by its polar structure and ability to form hydrogen bonds, making it an intriguing subject in solubility studies within chemical research.

Interesting facts

Interesting Facts about [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This compound presents a fascinating intersection between organic chemistry and biochemistry, serving as an important derivative in the realm of nucleoside research. Here are some key points that highlight its significance:

  • Nucleotide Analogue: As a derivative of purine, this compound is closely related to nucleotides, which are vital components of nucleic acids (DNA and RNA). Its structure allows it to mimic the naturally occurring building blocks of genetic material.
  • Biochemical Role: Compounds like this one can play a role in various biochemical pathways, including those involved in signaling and energy transfer within cells, due to the presence of the phosphate group.
  • Synthetic Applications: It has potential applications in drug development, particularly as a candidate for antiviral or anticancer therapies. The modified purine structure can exhibit altered biological activities that are beneficial in medicinal chemistry.
  • Research Interest: Because of its unique structure, the compound is a subject of ongoing research in various fields including pharmacology, molecular biology, and synthetic organic chemistry. Scientists are continually exploring its interactions and effects on biological systems.
  • Complexity Unveiled: The intricacies of such compounds challenge chemists to develop new synthetic strategies that can efficiently produce similar analogues with desired properties.

Overall, [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate showcases the interdisciplinary nature of modern chemistry, where understanding the nuances of molecular design can lead to breakthrough innovations in health and disease management.