Adefovir Dipivoxil | Solubility of Things

Identification

Molecular formula

C₁₀H₁₅N₅O₄P

CAS number

142340-99-6

IUPAC name

[[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonamidic acid

State

At room temperature, adefovir dipivoxil is a solid.

Melting point (Celsius)

118.00

Melting point (Kelvin)

391.15

Boiling point (Celsius)

480.50

Boiling point (Kelvin)

753.50

General information

Molecular weight

501.49g/mol

Molar mass

273.1960g/mol

Density

1.7000g/cm³

Appearence

Adefovir dipivoxil typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonamidic acid

The solubility of the compound with the chemical formula C₁₀H₁₅N₅O₄P can be influenced by several factors. The unique structure of this compound, which includes both hydrophobic and hydrophilic functional groups, plays a significant role in its solubility properties.

Key Factors Affecting Solubility:

Polarity: The presence of polar groups such as hydroxyl (–OH) and phosphoryl (–PO₄) likely increases solubility in polar solvents like water.
Hydrogen Bonding: Functional groups capable of hydrogen bonding enhance solubility in aqueous environments.
Size and Shape: The overall size and three-dimensional conformation of the molecule may affect intermolecular interactions, impacting solubility.
Temperature: As with many compounds, increasing temperature can improve solubility by facilitating dissolution processes.

In conclusion, while solubility data for this specific compound may not be readily available, its structural characteristics suggest that it could be moderately soluble in water and other polar solvents due to its composition. Understanding these solubility dynamics can provide deeper insights for applications in biological systems and pharmaceutical development.

Interesting facts

Interesting Facts about [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonamidic acid

[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonamidic acid is a fascinating compound that bridges the worlds of biochemistry and medicinal chemistry. Here are several captivating aspects of this unique compound:

Phosphorylation Links: This compound features a phosphoryl group, which plays a crucial role in biological processes such as energy transfer and signal transduction.
Purine Derivative: The presence of a purine structure indicates potential applications in nucleic acid chemistry, offering possibilities for developing antibiotics or antiviral agents.
Hydroxyl Groups: The inclusion of multiple hydroxy groups suggests enhanced reactivity and potential interactions with biological targets, paving the way for therapeutic applications.
Sugar Analog: This molecule is a tetrahydrofuran derivative, akin to sugar, which can influence its metabolism and role within biological systems.
Innovation in Therapeutics: Due to its complex structure, this compound could emerge as an innovative scaffold for drug design, impacting areas such as cancer and viral diseases.

In the realm of drug discovery, compounds like this one are essential as they can lead to breakthroughs in understanding disease mechanisms and developing new therapies. Overall, [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonamidic acid exemplifies the intricate and vital role of chemistry in advancing medicine.