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Calcitriol

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Identification
Molecular formula
C27H44O3
CAS number
32222-06-3
IUPAC name
5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol
State
State

At room temperature, calcitriol is in a solid state. It is typically provided in powder form for pharmaceutical use.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
525.00
Boiling point (Kelvin)
798.15
General information
Molecular weight
416.65g/mol
Molar mass
416.6470g/mol
Density
0.9711g/cm3
Appearence

Calcitriol appears as a white, crystalline powder that is practically insoluble in water, freely soluble in ethanol, and soluble in fatty oils. It is chemically known as 1,25-dihydroxycholecalciferol and has a crystalline texture.

Comment on solubility

Solubility of 5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol (C27H44O3)

The solubility of the compound 5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol is influenced by several structural characteristics, as it is a complex organic molecule. This compound features a large organic structure with hydrophobic features due to the long carbon chains, making solubility in water quite limited. Here are some key factors to consider:

  • Hydrophobicity: The presence of bulky alkyl groups contributes to a hydrophobic character, often resulting in low solubility in polar solvents such as water.
  • Polarity: The molecule's structure includes hydroxyl (-OH) groups that increase polarity but may not be sufficient to enhance solubility significantly due to the competing hydrophobic portions.
  • Solvent Compatibility: This compound is more likely to dissolve in non-polar solvents, such as oils or organic solvents, rather than in polar solvents.

In summary, while 5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol may exhibit limited solubility in water, it is likely to show much greater solubility in non-polar solvents. This reflects the classic principle that "like dissolves like,” emphasizing the importance of molecular structure in determining solubility behavior.

Interesting facts

Exploring 5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol

This fascinating compound, known for its complex structure and unique properties, offers numerous points of intrigue for both scientists and students alike. Here are some engaging facts about it:

  • Structural Complexity: The intricate arrangement of atoms in this compound showcases the beauty of organic chemistry. The presence of multiple ring structures, branches, and functional groups exemplifies the versatility of organic compounds.
  • Potential Applications: Researchers are continually exploring the applications of compounds like this one in various fields. Its unique properties may make it suitable for use in pharmaceuticals, agrochemicals, or materials science.
  • Therapeutic Insights: Due to its structural characteristics, this compound could exhibit interesting biological activities. The study of such compounds often leads to discoveries surrounding mechanisms of action, paving the way for new therapeutic agents.
  • Natural Products: Many compounds with similar complex frameworks are derived from natural sources. Investigating this compound may provide insights into how nature synthesizes such intricate molecules.
  • Isomerism: Like many organic compounds, this compound may possess several isomers, which can have drastically different properties and effects, an aspect that makes its study both challenging and rewarding.
  • Environmental Impact: Understanding the behavior and degradation of such compounds in the environment is crucial. They could have implications for sustainability and ecological health, spurring discussions on their lifecycle and environmental fate.

In summary, the complexity and potential of 5-[2-[1-(1,5-dimethylhexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol make it a compelling subject of study in the vast field of chemistry. As research progresses, this compound could yield insights that further our understanding of both organic chemistry and its applications in real-world scenarios.

Synonyms
alfacalcidol
41294-56-8
63181-13-5
Alfacalcidol?
1|A-Hydroxy Vitamin D3
Alfacalcidol EP Impurity A
PD154714
5-{2-[7a-methyl-1-(6-methylheptan-2-yl)-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol