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Budesonide

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Identification
Molecular formula
C25H34O6
CAS number
51333-22-3
IUPAC name
5-[2-[1-[1-(3-hydroxy-3-methyl-butoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol
State
State

Solid

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
430.53g/mol
Molar mass
430.5340g/mol
Density
1.2800g/cm3
Appearence

Budesonide is a white to off-white powder.

Comment on solubility

Solubility of 5-[2-[1-[1-(3-hydroxy-3-methyl-butoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol

The compound with the chemical formula C25H34O6 presents a complex structure that influences its solubility characteristics.

Factors Affecting Solubility:

  • Hydrophilicity and Hydrophobicity: The presence of hydroxyl (-OH) groups in the molecule contributes to its hydrophilic nature, potentially enhancing solubility in polar solvents like water.
  • Molecular Weight: With a relatively high molecular weight of 434.54 g/mol, solubility may be limited, especially in non-polar solvents.
  • Spatial Conformation: The bulkiness of certain groups may hinder the approach of solvent molecules, affecting dissolution rates.

Empirical observations suggest that:

  • This compound is likely to be better soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Conversely, solubility in water may be restricted due to the overall hydrophobic character that the larger hydrocarbon portion introduces.

In summary, while the functional groups indicate potential for solubility in polar environments, the balance of hydrophilic and hydrophobic elements, along with overall molecular complexity, can lead to variable solubility profiles that require experimental validation.

Interesting facts

Interesting Facts about 5-[2-[1-[1-(3-hydroxy-3-methyl-butoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol

This complex organic compound showcases the fascinating world of synthetic chemistry. It is particularly notable for its intricate structural design and diverse functional groups. Here are some intriguing aspects:

  • Multifunctionality: The compound contains multiple functional groups, specifically hydroxyl and alkene moieties, enhancing its potential for various chemical reactions and applications.
  • Potential Applications: Due to its unique structure, this compound could be explored for use in pharmaceuticals or as a starting material in organic synthesis, potentially leading to new drug development.
  • Stereochemistry: The presence of chiral centers in its structure suggests that the compound could exhibit stereoisomerism, leading to different compound variations that may have distinct biological activities.
  • Hydrophobic and Hydrophilic Properties: The combination of hydrophobic alkyl chains and hydrophilic hydroxyl groups allows for interesting interactions with biological membranes, which could be important in drug delivery systems.
  • Inspiration from Nature: The design of such molecules often takes inspiration from natural products, where complex structures play crucial roles in bioactivity.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." The exploration of this compound exemplifies how intricate chemical designs can lead to innovative research avenues and potentially impactful discoveries.

Given its elaborate structure, studying compounds like this can deepen our understanding of molecular interactions and pave the way for advancements in material science and medicinal chemistry.

Synonyms
132071-85-3
5-[2-[1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
103909-75-7
MC 1292
1217872-70-2
169218-34-2
DTXSID60861174
20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol