Skip to main content

5-(1,4-diazepan-1-ylsulfonyl)isoquinoline

ADVERTISEMENT
Identification
Molecular formula
C15H17N3O2S
CAS number
933365-07-0
IUPAC name
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
State
State

At room temperature, this compound is in a solid state. It's typically stable under standard conditions and should be stored in a cool, dry place to maintain its structural integrity and effectiveness.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
491.00
Boiling point (Kelvin)
764.15
General information
Molecular weight
291.38g/mol
Molar mass
291.3520g/mol
Density
1.3600g/cm3
Appearence

This compound generally appears as a solid at room temperature, often presenting as a white to off-white crystalline powder. The appearance may vary slightly based on the level of impurities and the form of crystallization.

Comment on solubility

Solubility of 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline

The solubility of 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline (C15H17N3O2S) is an intriguing topic worth exploring due to its complex structure and unique functional groups.

Solubility Characteristics:

  • Polarity: The presence of a sulfonyl group as well as multiple nitrogen atoms in its structure indicates a potential for polar character, which may enhance solubility in polar solvents.
  • Solvent Interaction: The compound is likely to be more soluble in polar solvents such as water or methanol compared to nonpolar solvents like hexane.
  • pH Dependence: Solubility may also vary with pH, due to the ionizable amine groups in the diazepane moiety, meaning it could have increased solubility under acidic or basic conditions.
  • Temperature Influence: As is common with many organic compounds, an increase in temperature may enhance solubility by disrupting intermolecular interactions.

In summary, while specific solubility data for 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline can provide precise insight, understanding its behavior in various solvents and conditions helps elucidate its chemical properties and potential applications. The compound’s unique structure may allow for interesting solubility profiles that are worth investigating.

Interesting facts

Interesting Facts about 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline

The compound 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline represents a fascinating intersection of medicinal chemistry and organic synthesis. This molecule is noteworthy due to its potential applications in the field of pharmaceuticals. Here are some interesting aspects:

  • Structural Diversity: The presence of both a diazepane ring and an isoquinoline structure contributes to its unique chemical properties and biological activities.
  • Biological Relevance: Compounds similar to this one have been explored for their effects on the central nervous system, making them potential candidates for neuropharmacological studies.
  • Drug Design: The sulfonamide moiety in this compound plays a crucial role in enhancing pharmacological efficacy through improved solubility and bioavailability.
  • Pharmacophore: Understanding the pharmacophore of this compound may lead to the discovery of new therapeutic agents, particularly in the treatment of anxiety and depression.
  • Research Studies: Ongoing research aims to investigate its mechanism of action and interactions with various biological targets, further unveiling the therapeutic potential of this intriguing compound.

As you explore the world of chemical compounds, consider the profound implications of such molecular structures on future drug developments. Each compound, like 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline, holds the potential key to unlocking new treatments for prevalent health issues, emphasizing the importance of continued research and innovation in the field of chemistry.

Synonyms
Fasudil
103745-39-7
ha-1077
HA 1077
AT 877
AT-877
HA1077
Fasudilum
Fasudil [INN]
1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
5-(1,4-diazepane-1-sulfonyl)isoquinoline
Fasudilum [INN-Latin]
1-(5-Isoquinolinesulfonyl)homopiperazine
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
AT877
Q0CH43PGXS
Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
Fasudil (INN)
NSC-759827
dihydrochloride fasudil
ZK-258594
FASUDIL [MI]
FASUDIL [WHO-DD]
5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE
Fasudil dihydrochloride
Hexahydro-1-(5-isoquinolylsulfonyl)-1H-1,4-diazepine
CHEMBL38380
DTXSID4048569
CHEBI:43871
NSC 759827
5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
Fasudilum (INN-Latin)
MFCD00866182
hexahydro-1-(5-isoquinolinesulfonyl)-1h-1,4-diazepine
N-(5-ISOQUINOLINESULFONYL)-1,4-PERHYDRODIAZEPINE
BRD7868
5-((HEXAHYDRO-1H-1,4-DIAZEPIN-1-YL)SULFONYL)ISOQUINOLINE
BRD-7868
ISOQUINOLINE, 5-((HEXAHYDRO-1H-1,4-DIAZEPIN-1-YL)SULFONYL)-
M77
NCGC00018100-04
UNII-Q0CH43PGXS
Fasudil?
2esm
2gni
Kinome_3390
Kinome_3391
Tocris-0541
1q8w
BiomolKI_000038
5-((1,4-diazepan-1-yl)sulfonyl)isoquinoline
BiomolKI2_000046
Fasudil (HA-1077)
SCHEMBL4674
BSPBio_001111
KBioGR_000451
KBioSS_000451
MLS006011953
cid_163751
GTPL5181
DTXCID9028201
BDBM14027
KBio2_000451
KBio2_003019
KBio2_005587
KBio3_000841
KBio3_000842
C04AX32
BCPP000234
Bio2_000386
Bio2_000866
HMS1362G13
HMS1792G13
HMS1990G13
HMS2089F13
HMS3264M10
Pharmakon1600-01502366
BCP26821
DEA74539
HY-10341A
NSC759827
NSC800098
AKOS009604905
AC-4279
AT27735
BCP9000678
CCG-100642
DB08162
NSC-800098
SDCCGSBI-0086761.P004
IDI1_002141
SMP2_000083
NCGC00018100-01
NCGC00018100-02
NCGC00018100-03
NCGC00018100-05
NCGC00018100-06
NCGC00018100-07
NCGC00024299-02
NCGC00024299-04
NCGC00024299-05
1-(5-Isoquinolinesulphonyl)homopiperazine
1-(5-Isoquinolinylsulfonyl)homopiperazine
1-(isoquinoline-5-sulfonyl)homopiperazine
AS-70114
SMR002529471
NS00068123
EN300-68842
D07941
MLS-0003155.0001
SBI-0086761.0001
AB00490076-08
AB00490076_09
1-(5-Isoquinolylsulfonyl)-1,4-diazaperhydroepine
Q5437132
BRD-K76617868-001-02-2
BRD-K76617868-001-03-0
BRD-K76617868-001-05-5
BRD-K76617868-003-10-1
BRD-K76617868-003-11-9
BRD-K76617868-003-14-3
BRD-K76617868-300-03-6
BRD-K76617868-300-04-4
Fasudil; (5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE
Z432085130
1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)- (9CI)
AT 877; AT-877; AT877; HA 1077; HA-1077; HA1077
816-154-4