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Epinephrine

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Identification
Molecular formula
C9H13NO3
CAS number
51-43-4
IUPAC name
5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]benzene-1,3-diol
State
State

At room temperature, epinephrine is typically in a solid state. It is commonly stored and handled as a small white to off-white crystalline powder.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
205.10
Boiling point (Kelvin)
478.25
General information
Molecular weight
183.20g/mol
Molar mass
183.2040g/mol
Density
1.2830g/cm3
Appearence

Epinephrine is typically seen as a colorless or light yellowish crystalline solid. It is usually available as a hydrochloride or bitartrate salt for medical and research purposes, often appearing as white crystalline powders.

Comment on solubility

Solubility of 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]benzene-1,3-diol

The solubility of the compound C9H13NO3 is influenced by its unique chemical structure and functional groups. As a phenolic compound, it exhibits both hydrophilic (water-attracting) and hydrophobic (water-repelling) characteristics, which are pivotal in determining how it interacts in various solvents.

  • Hydrophilic Regions: The presence of -OH (hydroxyl) groups contributes to its ability to form hydrogen bonds with water, often enhancing solubility in polar solvents.
  • Hydrophobic Regions: On the other hand, the aromatic components create a hydrophobic character, which may contribute to lower solubility in pure water.

Overall, the solubility of this compound can be characterized as:

  1. Variable: It may dissolve well in organic solvents due to its hydrophobic regions, while having moderate solubility in water.
  2. pH Dependent: The solubility may also vary with pH, as the ionization of hydroxyl groups can significantly alter its interactions in aqueous solutions.

In conclusion, the solubility of C9H13NO3 is a complex balance of its chemical structure, which makes it essential for applications in various fields, such as pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]benzene-1,3-diol

This complex compound holds significant interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. Here are some noteworthy aspects:

  • Pharmacological Relevance: The compound is characterized by its structural similarity to various pharmaceuticals, suggesting potential activity as an antioxidant and anti-inflammatory agent.
  • Biological Importance: Research indicates that derivatives of this compound may interact with hormonal pathways, potentially influencing estrogen-related processes such as cell proliferation.
  • Synthetic Pathways: The synthesis of this compound is of great interest due to its elaborate structure, involving multiple steps of functionalization and coupling reactions.
  • Mechanistic Studies: Understanding the mechanism of action at a molecular level can open avenues for the design of novel drugs that target specific pathways in diseases such as cancer.
  • Structure-Activity Relationship (SAR): Investigating how changes in the molecular structure impact biological activity is vital for optimizing the efficacy and safety of this compound and its analogs.

In summary, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]benzene-1,3-diol is not just a chemical compound but a promising entity that embodies the intricate relationship between structure and function in drug development. It reflects the ongoing efforts in chemistry to bridge the gap between basic research and application in health sciences.

Synonyms
fenoterol
13392-18-2
Phenoterol
Fenoterolum
Berotec
Fenoterolum [INN-Latin]
TH 1165
5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol
1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane
5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol
TH 1165A
Fenoterol [USAN:INN:BAN]
1-(p-Hydroxyphenyl)-2-((beta-hydroxy-beta-(3',5'-dihydroxyphenyl))ethyl)aminopropane
3,5-Dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyl alcohol
BRN 2157041
CHEBI:149226
Th-1165;Phenoterol
Th-1165a
CHEMBL32800
TH 1165A [AS HYDROBROMIDE SALT]
1,3-Benzenediol, 5-(1-hydroxy-2-((2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)-
5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol
TH 1165A FREE BASE
TH-1165A FREE BASE
DTXSID4023046
NSC 757811
Fenoterolum (INN-Latin)
Berotec (as hydrobromide)
Berotec [as hydrobromide]
NSC-757811
Benzyl alcohol, 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)-
p-Hydroxyphenylorciprenaline
p-Hydroxyphenyl-orciprenaline
Dosberotec
5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamino)ethyl)benzene-1,3-diol
Airum
CHEMBL537445
391234-95-0
TH-1165
1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-
3,5-Dihydroxy-.alpha.-(((p-hydroxy-.alpha.-methylphenethyl)amino)methyl)benzyl alcohol
1,3-Benzenediol,5-[(1S)-1-hydroxy-2-[[(1R)-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-
TH 1165A (AS HYDROBROMIDE SALT)
Fenoterol (USAN/INN)
p Hydroxyphenylorciprenaline
fenoterolo
p Hydroxyphenyl orciprenaline
Berodual n
5-(1-hydroxy-2-((1-(4-hydroxyphenyl)propan-2-yl)amino)ethyl)benzene-1,3-diol
5-(1-Hydroxy-2-(2-(4-hydroxy-phenyl)-1-methyl-ethylamino)-ethyl)-benzene-1,3-diol
Berotec 100
Berotec 200
Berotec (Salt/Mix)
Spectrum_001246
Partusisten (Salt/Mix)
Fenoterol [USAN:INN]
Prestwick0_000282
Prestwick1_000282
Prestwick2_000282
Prestwick3_000282
Spectrum2_001388
Spectrum3_000915
Spectrum4_001014
Spectrum5_001572
SCHEMBL5009
Lopac0_000544
BSPBio_000184
GTPL557
KBioGR_001507
KBioSS_001726
DivK1c_000405
SPBio_001376
SPBio_002403
BPBio1_000204
DTXCID903046
KBio1_000405
KBio2_001726
KBio2_004294
KBio2_006862
KBio3_001890
G02CA03
R03AC04
R03CC04
NINDS_000405
HMS3886D03
BCP29485
HY-B0976
BBL023034
BDBM50131281
BDBM50221768
s5769
STL356034
AKOS015964608
CCG-204634
CS-4466
DB01288
SDCCGSBI-0050527.P004
5-(1-hydroxy-2-{[2-(4-hydroxyphenyl)-1-methylethyl]amino}ethyl)benzene-1,3-diol
5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-1,3-benzenediol
IDI1_000405
NCGC00015430-02
NCGC00015430-03
NCGC00015430-11
NCGC00162181-01
AC-13630
DA-63411
FF171137
SBI-0050527.P003
AB00053590
NS00002340
D04157
G12550
AB00053590_10
EN300-18530961
L000255
Q420188
BRD-A97104540-004-04-4
BRD-A97104540-004-08-5
BRD-A97104540-004-15-0
Th-1165;Th 1165;Th1165; Phenoterol;Partusisten
1-(p-Hydroxyphenyl)-2-((.beta.-hydroxy-.beta.-(3',5'-dihydroxyphenyl))ethyl)aminopropane
Benzyl alcohol, 3,5-dihydroxy-.alpha.-(((p-hydroxy-.alpha.-methylphenethyl)amino)methyl)-
rac-(2S)-N-[(2R)-2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]-1-(4-hydroxyphenyl)propan-2-amonium bromide