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Salbutamol

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Identification
Molecular formula
C13H21NO3
CAS number
18559-94-9
IUPAC name
5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methyl-benzenesulfonamide
State
State

Salbutamol is usually a solid at room temperature, often available as a sulfate salt which is used in inhalers.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.00
Boiling point (Celsius)
960.00
Boiling point (Kelvin)
1 233.00
General information
Molecular weight
239.31g/mol
Molar mass
239.3120g/mol
Density
1.1388g/cm3
Appearence

The compound typically appears in a white to off-white crystalline powder form.

Comment on solubility

Solubility of 5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methyl-benzenesulfonamide

The solubility of the compound C13H21NO3 exhibits intriguing characteristics influenced by its structural composition. Here are some key points regarding its solubility:

  • Polarity: The presence of functional groups such as the sulfonamide and hydroxy moieties suggests a degree of polarity, which can enhance its solubility in polar solvents.
  • Solvent Interaction: This compound is likely to dissolve well in water due to the ability of its polar groups to form hydrogen bonds with water molecules.
  • User Guidance: It may show limited solubility in non-polar solvents, as its overall structure promotes an affinity for polar environments.
  • Temperature Dependence: Like many chemical compounds, its solubility may improve with increasing temperature, enhancing molecular interactions in solution.

In summary, the solubility profile of this compound is primarily influenced by its functional groups and their interactions with solvents. As the saying goes, "like dissolves like," and understanding the balance of polar and non-polar characteristics can provide insights into effective solvent choices.

Interesting facts

Interesting Facts about 5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methyl-benzenesulfonamide

This compound, known for its complex structure, offers a fascinating exploration into the realm of medicinal chemistry and pharmacology. Here are some intriguing aspects:

  • Structural Diversity: The compound features a unique blend of functional groups, including sulfonamide, which is known for its ability to inhibit various biological activities. This structural diversity is crucial in the development of targeted therapeutic agents.
  • Biological Activity: Sulfonamides are widely recognized for their antibacterial properties. They serve as a key class in antibiotic development and can also be influential in the treatment of other conditions, enhancing their medicinal value.
  • Mechanism of Action: The presence of the sulfonamide group allows this compound to mimic p-aminobenzoic acid (PABA), crucial for bacterial growth. This mimicking disrupts the synthesis of folate, thereby hindering bacterial reproduction.
  • Potential Applications: Researchers are continually investigating the potential applications of such compounds, with interests spanning areas like cancer research, diabetes treatment, and beyond.
  • Structure-Activity Relationship (SAR): The intricate arrangement of atoms within this compound provides a rich landscape for SAR studies. Understanding how variations in the structure affect biological potency is vital for drug design.
  • Research Significance: With ongoing studies, this compound stands as a testament to the advancements in pharmaceutical chemistry. Its potential modification could lead to the development of new and effective medications.

In essence, 5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methyl-benzenesulfonamide is more than just a name or formula; it represents the intricate dance between chemistry and therapeutic innovation. As stated by a renowned chemist, "In the molecular world, every atom counts, and each compound tells a story." This compound is certainly no exception!

Synonyms
Amosulalol
85320-68-9
Amosulalolum
Amosulalol [INN]
Amosulalolum [Latin]
5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methylbenzenesulfonamide
UNII-C69JI1BAU8
C69JI1BAU8
Amosulalol (INN)
AMOSULALOL [MI]
AMOSULALOL [WHO-DD]
(+-)-5-(1-Hydroxy-2-((2-(o-methoxyphenoxy)ethyl)amino)ethyl)-o-toluenesulfonamide
5-(1-hydroxy-2-((2-(2-methoxyphenoxy)ethyl)amino)ethyl)-2-methylbenzenesulfonamide
Amosulalolum (Latin)
(+/-)-5-(1-HYDROXY-2-((2-(O-METHOXYPHENOXY)ETHYL)AMINO)ETHYL)-O-TOLUENESULFONAMIDE
5-[1-Hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methylbenzenesulfonamide
SCHEMBL48933
CHEMBL152231
BDBM81882
DTXSID90868893
CHEBI:135592
LVEXHFZHOIWIIP-UHFFFAOYSA-N
KDA32068
AKOS030530805
5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methyl-benzenesulfonamide
TS-08674
CAS_93633-92-2
HY-106720
CS-0026410
NS00123320
D07451
L001814
Q4747983
5-{1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]-ethyl}-2-methylbenzenesulfonamide