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[5-(1-benzylindazol-3-yl)-2-furyl]methanol

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Identification
Molecular formula
C19H16N2O2
CAS number
309956-78-3
IUPAC name
[5-(1-benzylindazol-3-yl)-2-furyl]methanol
State
State
This compound is in a solid state at room temperature.
Melting point (Celsius)
148.50
Melting point (Kelvin)
421.65
Boiling point (Celsius)
423.00
Boiling point (Kelvin)
696.15
General information
Molecular weight
282.34g/mol
Molar mass
282.3150g/mol
Density
1.2400g/cm3
Appearence
The compound is typically a solid at room temperature with a crystalline form. Its coloration can vary depending on the purity and specific sample in question.
Comment on solubility

Solubility of [5-(1-benzylindazol-3-yl)-2-furyl]methanol

The compound [5-(1-benzylindazol-3-yl)-2-furyl]methanol, with the formula C19H16N2O2, exhibits interesting solubility characteristics that can significantly influence its practical applications. The solubility of organic compounds like this one can often be affected by their molecular structure, polarity, and the presence of functional groups.

Factors Influencing Solubility:

  • Polarity: The presence of hydroxyl (-OH) group in the structure tends to enhance solubility in polar solvents, such as water.
  • Hydrophobic Regions: The benzyl and indazole rings present in the compound contribute to hydrophobic interactions, which can reduce solubility in polar solvents.
  • Temperature: Generally, increasing temperature may enhance solubility, particularly in organic solvents.

It's crucial to note that the solubility can vary depending on the following conditions:

  • Solvent Type: Solubility may be greater in organic solvents like methanol or ethanol compared to water, due to the overall hydrophobic character of the molecule.
  • Chemical Interactions: Formation of hydrogen bonds with other molecules can also affect how well the compound dissolves.

In conclusion, while the solubility of [5-(1-benzylindazol-3-yl)-2-furyl]methanol may show favorable interactions in specific solvents, it is significantly influenced by its structural components, making it vital to consider these aspects when exploring its use in various applications.

Interesting facts

Interesting Facts About [5-(1-benzylindazol-3-yl)-2-furyl]methanol

[5-(1-benzylindazol-3-yl)-2-furyl]methanol is a fascinating compound that brings together unique structural features and potential applications in various fields. Here are some noteworthy points about this intriguing compound:

  • Structural Innovation: This compound showcases a hybrid structure composed of an indazole and a furyl fragment, leading to interesting electronic properties. Such hybrid structures can often result in unique interactions, making them suitable for diverse applications.
  • Pharmaceutical Potential: The indazole moiety is frequently encountered in drug discovery, as it has been linked to various biological activities. This makes [5-(1-benzylindazol-3-yl)-2-furyl]methanol a potential candidate for further research into therapeutic agents.
  • Research Interests: Compounds like this one have sparked the interest of researchers in the fields of medicinal chemistry and organic synthesis. The possibility of developing new drugs or materials from this compound opens diverse avenues for study.
  • Biological Activity: Compounds containing both furyl and indazole moieties have been reported to exhibit antimicrobial and anticancer properties. Understanding the mechanisms behind such activities can contribute to advancements in medicine.
  • Reaction Versatility: The presence of the hydroxyl group in [5-(1-benzylindazol-3-yl)-2-furyl]methanol provides abundant opportunities for reactions. This can facilitate modifications that potentially enhance the compound's efficacy or create derivative compounds with novel properties.

With its compelling structure and vast potential, [5-(1-benzylindazol-3-yl)-2-furyl]methanol stands as a spotlight example of how intricate organic compounds can lead to breakthroughs in both academic and industrial chemistry. As scientists continue to explore its characteristics and applications, we may uncover further significance of this compound in the world of chemistry.

Synonyms
yc-1
Lificiguat
170632-47-0
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
YC 1
3-(5'-Hydroxymethyl-2'-furyl)-1-benzylindazole
154453-18-6
Lificiguat [INN]
[5-(1-benzylindazol-3-yl)furan-2-yl]methanol
C19H16N2O2
5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol
515CC1WPTE
CHEMBL333985
3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole
3-(5/'-hydroxymethyl-2/'-furyl)-1-benzylindazole
NSC-728165
YC1
1-Benzyl-3-(5-hydroxymethyl-2-furyl)indazole
[5-(1-benzyl-1H-indazol-3-yl)furan-2-yl]methanol
[5-[1-(phenylmethyl)indazol-3-yl]furan-2-yl]methanol
YC 1 compound
YC-1 compound
SMR000857214
Lificiguat(YC-1)
[5-(1-benzyl-1h-indazol-3-yl)-2-furyl]methanol
SR-01000076202
UNII-515CC1WPTE
lificiguatum
YC-1; Lificiguat
MFCD06407798
YC-1, powder
YC-1(Lificiguat)?
Lopac-Y-102
LIFICIGUAT [WHO-DD]
Lopac0_001230
BSPBio_000987
KBioGR_000327
KBioSS_000327
MLS001333257
MLS001333258
MLS002172480
MLS006012048
SCHEMBL187837
GTPL5291
CHEBI:93060
KBio2_000327
KBio2_002895
KBio2_005463
KBio3_000653
KBio3_000654
DTXSID70165635
CHEBI:142430
Bio2_000324
Bio2_000804
HMS1362A09
HMS1792A09
HMS1990A09
HMS2235B17
HMS3263F22
HMS3373B12
HMS3403A09
HMS3649M04
KUC114162N
BCP09072
EX-A2409
VGA63247
Tox21_501230
BDBM50095469
HB3521
NSC728165
NSC756879
AKOS022180370
CCG-205304
CS-3363
LP01230
NSC 728165
NSC-756879
SDCCGSBI-0051197.P002
IDI1_002079
QTL1_000091
NCGC00016103-01
NCGC00016103-02
NCGC00016103-03
NCGC00016103-04
NCGC00016103-05
NCGC00016103-06
NCGC00016103-07
NCGC00016103-17
NCGC00094472-01
NCGC00094472-02
NCGC00094472-03
NCGC00094472-04
NCGC00261915-01
AC-29036
AS-55797
DA-29768
HY-14927
KSC-412-005-
EU-0101230
Y-102
1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole
3-(5-hydroxymethyl-2-furyl)-1-benzylindazole
A12138
1-Benzyl-3-(5'-hydroxymethyl-2-furyl)indazole
3-(5'-hydroxymethyl-2'furyl)-1-benzyl-indazole
1-Benzyl-3-(5-hydroxymethyl-2-furyl)-1H-indazole
SR-01000076202-1
SR-01000076202-7
BRD-K60476892-001-02-1
BRD-K60476892-001-11-2
Q27089256
[5-(1-Benzyl-1H-indazol-3-yl)-furan-2-yl]-methanol
1-(1-benzyl-3-(5''-hydroxymethyl-2''-furyl)-indazole
2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-
5-a[1-a?phenylmethyl)-a?H-aindazol-a?-ayl]-a?-afuranmethanol